公开(公告)号：US20230215717A1

公开(公告)日：2023-07-06

申请号：US17998012

申请日：2021-05-05

申请人： Micromass UK Ltd

发明人： Arvind Rangan ,  Carl Chen ,  Steven Rocha ,  Enchen Guo ,  Nicola Lumley ,  David Douce ,  Richard Gallagher ,  Kate Whyatt

IPC分类号： H01J49/16 ,  H01J49/04

CPC分类号： H01J49/168 ,  H01J49/0404 ,  H01J49/0477 ,  H01J49/049

摘要： An atmospheric pressure ionisation source comprising: an ionisation chamber, comprising an aperture for receiving at least the distal end of a capillary into the ionisation chamber in use, the aperture having a capillary axis; a desolvation heater having a nozzle, for directing a stream of heated gas onto the distal end of the capillary in use, the nozzle having a nozzle axis; a corona discharge device including a corona pin having a corona axis, the corona pin for ionizing a sample in the ionisation chamber in use; and an inlet cone of a mass spectrometer arranged in the ionisation chamber, the inlet cone defining a cone entrance having a cone axis, wherein the cone axis is substantially coaxial with the corona axis and the capillary axis is substantially perpendicular to and intersects with the nozzle axis.