公开(公告)号：US20230170200A1

公开(公告)日：2023-06-01

申请号：US17998005

申请日：2021-05-05

申请人： Micromass UK Ltd

发明人： Arvind Rangan ,  Veronica Lum ,  Carl Chen ,  Steven Rocha ,  Enchen Guo ,  Nicola Lumley ,  David Douce

IPC分类号： H01J49/04

CPC分类号： H01J49/0404 ,  H01J49/0431 ,  H01J49/0459

摘要： A nozzle for directing heated gas onto the distal end of a capillary arrangable adjacent the nozzle, the nozzle comprising: a housing defining a plenum for heated gas; and at outlet comprising at least one aperture fluidly connected to the plenum, the outlet configured to direct a curtain of the heated gas onto the distal end of a capillary in use, such that the curtain of heated gas is substantially aligned with the longitudinal axis of the capillary.

公开(公告)号：US20230215717A1

公开(公告)日：2023-07-06

申请号：US17998012

申请日：2021-05-05

申请人： Micromass UK Ltd

发明人： Arvind Rangan ,  Carl Chen ,  Steven Rocha ,  Enchen Guo ,  Nicola Lumley ,  David Douce ,  Richard Gallagher ,  Kate Whyatt

IPC分类号： H01J49/16 ,  H01J49/04

CPC分类号： H01J49/168 ,  H01J49/0404 ,  H01J49/0477 ,  H01J49/049

摘要： An atmospheric pressure ionisation source comprising: an ionisation chamber, comprising an aperture for receiving at least the distal end of a capillary into the ionisation chamber in use, the aperture having a capillary axis; a desolvation heater having a nozzle, for directing a stream of heated gas onto the distal end of the capillary in use, the nozzle having a nozzle axis; a corona discharge device including a corona pin having a corona axis, the corona pin for ionizing a sample in the ionisation chamber in use; and an inlet cone of a mass spectrometer arranged in the ionisation chamber, the inlet cone defining a cone entrance having a cone axis, wherein the cone axis is substantially coaxial with the corona axis and the capillary axis is substantially perpendicular to and intersects with the nozzle axis.

公开(公告)号：US20230178351A1

公开(公告)日：2023-06-08

申请号：US17998000

申请日：2021-05-05

申请人： Micromass UK Ltd

发明人： Pham Hoang Vu Ngo ,  Arvind Rangan ,  Veronica Lum ,  Carl Chen ,  Nicola Lumley ,  David Douce

IPC分类号： H01J49/04

CPC分类号： H01J49/0404

摘要： A holder for a capillary, comprising: a housing having a passage to receive a capillary; and a clamping mechanism configurable between: an engaged state in which the clamping mechanism is configured to retain a capillary receivable in the passage in use; and a disengaged state in which the clamping mechanism is configured to allow insertion/removal of a capillary in the passage in use; and a release mechanism operatively associated with the clamping mechanism and movable between a first position, in which the clamping mechanism is configured in said engaged state; and a second position, in which the clamping mechanism is configured in aid disengaged state, wherein the release mechanism is configured to bias the clamping mechanism towards the engaged state, wherein the passage in the housing comprises an end stop, configured to abut the end of a capillary inserted in the passage in use.