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公开(公告)号：US20130323261A1
公开(公告)日：2013-12-05
申请号：US13957679
申请日：2013-08-02
IPC分类号： A61K39/395
CPC分类号： A61K39/39591 , A61K31/519 , A61K39/3955 , A61K47/22 , A61K47/26 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K1/18 , C07K1/36 , C07K16/065 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/94
摘要： The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
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公开(公告)号：US20130309242A1
公开(公告)日：2013-11-21
申请号：US13957006
申请日：2013-08-01
IPC分类号： A61K39/395
CPC分类号： A61K39/39591 , A61K31/519 , A61K39/3955 , A61K47/22 , A61K47/26 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K1/18 , C07K1/36 , C07K16/065 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/94
摘要： The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
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公开(公告)号：US20110002935A1
公开(公告)日：2011-01-06
申请号：US12882601
申请日：2010-09-15
IPC分类号： A61K39/395 , C07K16/00 , C07K1/18 , C07K16/24
CPC分类号： A61K39/39591 , A61K31/519 , A61K39/3955 , A61K47/22 , A61K47/26 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K1/18 , C07K1/36 , C07K16/065 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/94
摘要： The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
摘要翻译： 本发明提供从包含抗体和至少一种HCP的混合物制备宿主细胞蛋白质（HCP）还原抗体制备物的方法，所述混合物包含离子交换分离步骤，其中混合物经受第一离子交换材料，使得 获得HCP还原的抗体制剂。
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公开(公告)号：US07863426B2
公开(公告)日：2011-01-04
申请号：US11732918
申请日：2007-04-04
IPC分类号： A61K39/395 , C07K16/00 , C07K1/18
CPC分类号： A61K39/39591 , A61K31/519 , A61K39/3955 , A61K47/22 , A61K47/26 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K1/18 , C07K1/36 , C07K16/065 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/94
摘要： The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
摘要翻译： 本发明提供从包含抗体和至少一种HCP的混合物制备宿主细胞蛋白质（HCP）还原抗体制备物的方法，所述混合物包含离子交换分离步骤，其中混合物经受第一离子交换材料，使得 获得HCP还原的抗体制剂。
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公开(公告)号：US20070292442A1
公开(公告)日：2007-12-20
申请号：US11732918
申请日：2007-04-04
IPC分类号： A61K39/395 , A61P19/02 , A61P29/02 , C07K16/00 , C07K16/18
CPC分类号： A61K39/39591 , A61K31/519 , A61K39/3955 , A61K47/22 , A61K47/26 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K1/18 , C07K1/36 , C07K16/065 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/94
摘要： The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
摘要翻译： 本发明提供从包含抗体和至少一种HCP的混合物制备宿主细胞蛋白质（HCP）还原抗体制备物的方法，所述混合物包含离子交换分离步骤，其中混合物经受第一离子交换材料，使得 获得HCP还原的抗体制剂。
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公开(公告)号：US20130273059A1
公开(公告)日：2013-10-17
申请号：US13927236
申请日：2013-06-26
IPC分类号： C07K16/24
CPC分类号： A61K39/39591 , A61K31/519 , A61K39/3955 , A61K47/22 , A61K47/26 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K1/18 , C07K1/36 , C07K16/065 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/94
摘要： The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
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公开(公告)号：US20130280267A1
公开(公告)日：2013-10-24
申请号：US13927576
申请日：2013-06-26
IPC分类号： A61K39/395
CPC分类号： A61K39/39591 , A61K31/519 , A61K39/3955 , A61K47/22 , A61K47/26 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K1/18 , C07K1/36 , C07K16/065 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/94
摘要： The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
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公开(公告)号：US08231876B2
公开(公告)日：2012-07-31
申请号：US12882601
申请日：2010-09-15
IPC分类号： A61K39/395 , C07K16/00
CPC分类号： A61K39/39591 , A61K31/519 , A61K39/3955 , A61K47/22 , A61K47/26 , A61K2039/505 , A61K2039/54 , A61K2039/545 , C07K1/18 , C07K1/36 , C07K16/065 , C07K16/241 , C07K2317/14 , C07K2317/21 , C07K2317/94
摘要： The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
摘要翻译： 本发明提供从包含抗体和至少一种HCP的混合物制备宿主细胞蛋白质（HCP）还原抗体制备物的方法，所述混合物包含离子交换分离步骤，其中混合物经受第一离子交换材料，使得 获得HCP还原的抗体制剂。
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公开(公告)号：US20140341843A1
公开(公告)日：2014-11-20
申请号：US14235777
申请日：2012-07-27
申请人： Thomas M. Barnes , Jinzhao Hou , Gregory Zarbis-Papastoitsis , Emily Belcher Schirmer , Gary L. McNeil , Kathryn Golden
发明人： Thomas M. Barnes , Jinzhao Hou , Gregory Zarbis-Papastoitsis , Emily Belcher Schirmer , Gary L. McNeil , Kathryn Golden
IPC分类号： C07K14/545 , B01D15/36
CPC分类号： C07K14/545 , A61K38/00 , B01D15/1864 , B01D15/362 , B01D15/363 , B01D15/3847 , C07K14/54 , Y02A50/473
摘要： The present invention provides methods and compositions for the preparation and delivery of chimeric cytokine proteins, including cell cultures, methods of purification and purified compositions.
摘要翻译： 本发明提供了用于制备和递送嵌合细胞因子蛋白质的方法和组合物，包括细胞培养物，纯化方法和纯化的组合物。
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