Heat-sensing protein switches and uses thereof

    公开(公告)号:US10377807B2

    公开(公告)日:2019-08-13

    申请号:US15191902

    申请日:2016-06-24

    IPC分类号: C07K14/705 G01N33/68

    摘要: A region of the TRPV1 protein that functions as a temperature switch (FIG. 1) has been identified, and can be expressed, purified and applied in combination with other proteins. The function of the switch is maintained even when the region or domain is isolated from the entire protein. As the protein domain is a temperature switch, it can be used to control other proteins and signaling pathways in vitro and in vivo; and TRPV1 is a therapeutic target that is being pursued primarily for intervention in pain (neuropathic and inflammatory) and cancer.

    MOBILE TERMINAL AND CONTROLLING METHOD THEREOF
    5.
    发明申请
    MOBILE TERMINAL AND CONTROLLING METHOD THEREOF 有权
    移动终端及其控制方法

    公开(公告)号:US20120011438A1

    公开(公告)日:2012-01-12

    申请号:US13048785

    申请日:2011-03-15

    IPC分类号: G06F3/041 G06F3/01

    摘要: A mobile terminal is disclosed. According to one embodiment, the mobile terminal includes: a housing including a front side, a rear side and a plurality of lateral sides; a touchscreen located on the front side of the housing, configured to display at least one touch-executable object, and including a predefined edge region; and a controller. The controller is configured to preempt execution of a function corresponding to a particular object of the at least one touch-executable object if a first touch of the particular object is detected in the predefined edge region of the touchscreen.

    摘要翻译: 公开了一种移动终端。 根据一个实施例,移动终端包括:壳体,包括前侧,后侧和多个侧边; 触摸屏,其位于所述壳体的前侧,被配置为显示至少一个触摸可执行对象,并且包括预定边缘区域; 和控制器。 如果在触摸屏的预定边缘区域中检测到特定对象的第一触摸,则控制器被配置为抢占与至少一个触摸可执行对象的特定对象相对应的功能的执行。

    HEAT-SENSING PROTEIN SWITCHES AND USES THEREOF
    6.
    发明申请
    HEAT-SENSING PROTEIN SWITCHES AND USES THEREOF 审中-公开
    热感应蛋白质开关及其用途

    公开(公告)号:US20160376338A1

    公开(公告)日:2016-12-29

    申请号:US15191902

    申请日:2016-06-24

    IPC分类号: C07K14/705 G01N33/68

    摘要: A region of the TRPV1 protein that functions as a temperature switch (FIG. 1) has been identified, and can be expressed, purified and applied in combination with other proteins. The function of the switch is maintained even when the region or domain is isolated from the entire protein. As the protein domain is a temperature switch, it can be used to control other proteins and signaling pathways in vitro and in vivo; and TRPV1 is a therapeutic target that is being pursued primarily for intervention in pain (neuropathic and inflammatory) and cancer.

    摘要翻译: 已经鉴定了作为温度开关(图1)起作用的TRPV1蛋白质的区域,并且可以表达,纯化并与其它蛋白质组合应用。 即使当区域或结构域与整个蛋白质分离时,也保持开关的功能。 由于蛋白质结构域是温度开关,因此可用于体外和体内控制其他蛋白质和信号通路; TRPV1是一种主要用于干预疼痛(神经病和炎症)和癌症的治疗靶点。

    Mobile terminal and controlling method thereof
    7.
    发明授权
    Mobile terminal and controlling method thereof 有权
    移动终端及其控制方法

    公开(公告)号:US08713463B2

    公开(公告)日:2014-04-29

    申请号:US13048785

    申请日:2011-03-15

    IPC分类号: G06F3/00

    摘要: A mobile terminal is disclosed. According to one embodiment, the mobile terminal includes: a housing including a front side, a rear side and a plurality of lateral sides; a touchscreen located on the front side of the housing, configured to display at least one touch-executable object, and including a predefined edge region; and a controller. The controller is configured to preempt execution of a function corresponding to a particular object of the at least one touch-executable object if a first touch of the particular object is detected in the predefined edge region of the touchscreen.

    摘要翻译: 公开了一种移动终端。 根据一个实施例,移动终端包括:壳体,包括前侧,后侧和多个侧边; 触摸屏,其位于所述壳体的前侧,被配置为显示至少一个触摸可执行对象,并且包括预定边缘区域; 和控制器。 如果在触摸屏的预定边缘区域中检测到特定对象的第一触摸,则控制器被配置为抢占与至少一个触摸可执行对象的特定对象相对应的功能的执行。

    Mobile terminal and method for controlling mobile terminal
    8.
    发明授权
    Mobile terminal and method for controlling mobile terminal 有权
    移动终端和移动终端控制方法

    公开(公告)号:US08654091B2

    公开(公告)日:2014-02-18

    申请号:US13103945

    申请日:2011-05-09

    IPC分类号: G06F3/048

    CPC分类号: H04M1/72544 H04M1/72577

    摘要: A mobile terminal is provided. The mobile terminal comprises: a touchscreen controllable to display at least one home screen or a lock screen; and a controller configured to: control the touchscreen to display the at least one home screen when the mobile terminal is in a standby state, one of the at least one home screen displaying at least one application object including one or more widget objects; and control the touchscreen to display the lock screen when the mobile terminal is switched from the standby state to a locked state. The lock screen displays a specific widget object of the one or more widget objects if the specific widget object was selected by a user for the lock screen.

    摘要翻译: 提供移动终端。 移动终端包括:可控的显示至少一个主屏幕或锁屏的触摸屏; 以及控制器,被配置为:当所述移动终端处于待机状态时,控制所述触摸屏以显示所述至少一个主屏幕,所述至少一个主屏幕中的一个显示包括一个或多个窗口小部件对象的至少一个应用对象; 并且当移动终端从待机状态切换到锁定状态时,控制触摸屏以显示锁定屏幕。 如果用户为锁定屏幕选择了特定的小部件对象,则锁定屏幕将显示一个或多个小部件对象的特定小部件对象。

    Mobile terminal and touch recognizing method therein
    9.
    发明授权
    Mobile terminal and touch recognizing method therein 有权
    移动终端和触摸识别方法

    公开(公告)号:US09128527B2

    公开(公告)日:2015-09-08

    申请号:US13287062

    申请日:2011-11-01

    IPC分类号: G06F3/01 G06F3/042 G06F3/0488

    摘要: A mobile terminal and touch recognizing method therein are disclosed, by which a multi-touch can be recognized. The present invention includes receiving a plurality of touches simultaneously using a touchscreen, consecutively receiving a plurality of images including a plurality of the received touches for a predetermined time using a camera provided under the touchscreen, determining patterns and pattern changes of a plurality of the touches included in a plurality of the images, respectively, and recognizing a gesture by a plurality of the touches in accordance with a result of the determining step. Moreover, the touch pattern includes at least one selected from the group consisting of a touch number, a touch point, a touch size and a touch figure.

    摘要翻译: 公开了一种移动终端及其触摸识别方法,可以识别多点触摸。 本发明包括使用触摸屏同时接收多个触摸,使用设置在触摸屏下方的相机连续地接收包括多个接收的触摸的多个图像,确定多个触摸的图案和图案变化 分别包括在多个图像中,并且根据确定步骤的结果识别多个触摸的手势。 此外,触摸图案包括从由触摸号码,触摸点,触摸尺寸和触摸图形组成的组中选择的至少一个。

    Mobile terminal and controlling method thereof
    10.
    发明授权
    Mobile terminal and controlling method thereof 有权
    移动终端及其控制方法

    公开(公告)号:US08571521B2

    公开(公告)日:2013-10-29

    申请号:US13081368

    申请日:2011-04-06

    IPC分类号: H04M1/68

    摘要: A method of controlling a mobile terminal by displaying simultaneously a plurality of menu icons comprising at least one restricted use icon and at least one non-restricted use icon; performing a user authentication procedure responsive to user selection of the at least one restricted use icon; and unlocking the mobile terminal responsive to user selection of the at least one non-restricted use icon or responsive to completion of the user authentication procedure.

    摘要翻译: 一种通过同时显示包括至少一个受限使用图标和至少一个非限制使用图标的多个菜单图标来控制移动终端的方法; 响应于所述至少一个受限使用图标的用户选择执行用户认证过程; 以及响应于所述至少一个非受限使用图标的用户选择或响应于所述用户认证过程的完成来解锁所述移动终端。