公开(公告)号：US08560049B2

公开(公告)日：2013-10-15

申请号：US13283948

申请日：2011-10-28

申请人： Yoshimori Kassai ,  Mitsue Miyazaki ,  Satoshi Sugiura

发明人： Yoshimori Kassai ,  Mitsue Miyazaki ,  Satoshi Sugiura

IPC分类号： A61B5/05

CPC分类号： A61B5/055 ,  A61B5/0456 ,  A61B5/7207 ,  A61B5/7257 ,  A61B5/7285 ,  G01R33/4828 ,  G01R33/5605 ,  G01R33/5607 ,  G01R33/5615 ,  G01R33/5617 ,  G01R33/5635 ,  G01R33/5673

摘要： A magnetic resonance imaging (MRI) system obtains an MR image of an object. The system detects an ECG signal and performs a pulse sequence of RF gradient magnetic fields toward the object. Imaging defined by the pulse sequence is longer in temporal length than one heartbeat. The system further acquires an MR signal from the object in response to performance of the pulse sequence and produces the MR image based on the acquired MR signal. Also possible are: a plurality of divided MT pulses instead of the conventional single MT pulse, an SE-system pulse sequence having a shorter echo train spacing, and the generation of sounds by applying gradient pulses incorporated in an imaging pulse sequence so as to automatically instruct a patient to perform an intermittent breath hold.

公开(公告)号：US07647086B2

公开(公告)日：2010-01-12

申请号：US10678309

申请日：2003-10-06

申请人： Mitsue Miyazaki ,  Satoshi Sugiura

发明人： Mitsue Miyazaki ,  Satoshi Sugiura

IPC分类号： A61B5/05

CPC分类号： G01R33/56308 ,  G01R33/56316

摘要： A magnetic resonance imaging apparatus includes an RF coil unit which generates RF pulses toward a subject, and which receives an MR signal from the subject. Gradient magnetic field coils generate a gradient magnetic field for slice selection, a gradient magnetic field for phase encoding and a gradient magnetic field for frequency encoding, respectively. An arithmetic unit generates image data on the basis of the MR signal, and a sequence controller controls phase encoding gradient magnetic field coils in order to generate flow pulses for dephasing or rephasing the MR spin of blood flow within the subject, in the same direction as that of the phase encoding gradient magnetic field.

摘要翻译： 磁共振成像装置包括：向被检体产生RF脉冲的RF线圈单元，并从受检者接收MR信号。 梯度磁场线圈分别产生用于切片选择的梯度磁场，用于相位编码的梯度磁场和用于频率编码的梯度磁场。 算术单元根据MR信号生成图像数据，并且序列控制器控制相位编码梯度磁场线圈，以便产生用于使对象内的血流的MR自旋的相位相移或重新定位的流动脉冲，与 相位编码梯度磁场。

公开(公告)号：US06320377B1

公开(公告)日：2001-11-20

申请号：US09048290

申请日：1998-03-26

申请人： Mitsue Miyazaki ,  Satoshi Sugiura

发明人： Mitsue Miyazaki ,  Satoshi Sugiura

IPC分类号： G01V300

CPC分类号： G01R33/4838 ,  A61B5/055 ,  A61B6/541 ,  G01R33/563

摘要： An artery vein visually separated MRA image and/or a higher blood/parenchyma contrast MRA image are provided by a magnetic resonance imaging system. The system comprises, in addition to a magnet generating a static magnetic field, a gradient generation unit generating magnetic gradients superimposed on the static magnetic field, a transmission/reception unit transmitting to a subject spin-exciting RF signal and receiving an MR signal emanated from the subject, a reconstruction unit reconstructing the image based on the MR, and a sequencer for performing a scan sequence of pulses through control of the gradient generation unit and the transmission/reception unit. The scan sequence of pulses is formed for producing the functions of: applying not only a plurality of saturation pulses in time series to a pre-saturated slice positionally different from the imaging slice but also a slice gradient pulse for selecting the pre-saturated slice concurrently with the plurality of saturation pulses, and performing a data acquisition sequence applying to the imaging slice a pulse train for acquiring an MR signal from the imaging slice after application of the plurality of saturation pulses and the slice gradient pulse.

摘要翻译： 通过磁共振成像系统提供动脉静脉视觉上分离的MRA图像和/或较高的血液/实质对比MRA图像。 除了产生静磁场的磁体之外，该系统还包括产生叠加在静磁场上的磁梯度的梯度产生单元，发送到主体旋转激励RF信号的发送/接收单元，并且接收从MR发送的MR信号 主体，基于MR重建图像的重建单元，以及用于通过梯度生成单元和发送/接收单元的控制来执行脉冲扫描序列的定序器。 脉冲的扫描序列被形成用于产生以下功能：不仅将时间序列中的多个饱和脉冲施加到与成像片位置不同的预饱和片，而且还用于同时选择预饱和片的片梯度脉冲 以及多个饱和脉冲，并且在施加所述多个饱和脉冲和所述切片梯度脉冲之后，对所述成像切片执行用于从所述成像切片获取MR信号的脉冲序列的数据采集序列。

公开(公告)号：US08710838B2

公开(公告)日：2014-04-29

申请号：US12971517

申请日：2010-12-17

申请人： Mitsue Miyazaki ,  Satoshi Sugiura

发明人： Mitsue Miyazaki ,  Satoshi Sugiura

IPC分类号： G01V3/00

CPC分类号： G01R33/5635 ,  G01R33/482 ,  G01R33/56316

摘要： A magnetic resonance imaging apparatus includes the data gathering unit gathers magnetic resonance data in a non-contrast manner by applying a first readout gradient pulse having a zero-order moment of 0 and second readout gradient pulse having a zero-order moment of 0 and a first-order moment of a value different from a value of a first-order moment of the first readout gradient pulse to a region of interest including a fluid in motion, and periodically arranging first magnetic resonance data readout with the first readout gradient pulse and second magnetic resonance data read out with the second readout gradient pulse in at least one of a phase encoding direction and a slice encoding direction in a k-space to generate k-space data and reconstructs the k-space data to generate an image in which a fluid image and static part image surrounding the fluid are spatially separated from each other.

摘要翻译： 磁共振成像装置包括数据采集单元，通过应用具有零阶矩为0的第一读出梯度脉冲和零阶矩为0的第二读出梯度脉冲以及非零对数方式来收集磁共振数据 一阶矩，其值与第一读出梯度脉冲的一阶矩的值不同于包括运动中的流体的感兴趣区域，并且周期性地布置具有第一读出梯度脉冲和第二读出梯度脉冲的第一磁共振数据读出 在k空间中的相位编码方向和切片编码方向中的至少一个中用第二读出梯度脉冲读出磁共振数据，以产生k空间数据，并且重建k空间数据以产生其中 流体图像和围绕流体的静态部分图像在空间上彼此分离。

公开(公告)号：US08515526B2

公开(公告)日：2013-08-20

申请号：US12694610

申请日：2010-01-27

申请人： Mitsue Miyazaki ,  Satoshi Sugiura

发明人： Mitsue Miyazaki ,  Satoshi Sugiura

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  G01R33/5602 ,  G01R33/5614 ,  G01R33/56333 ,  G01R33/5635 ,  G01R33/56366

摘要： A magnetic resonance imaging apparatus includes a first blood flow image acquisition unit and a second blood flow image acquisition unit. The first blood flow image acquisition unit acquires a first blood flow image of a breast of an object without contrast medium. The second blood flow image acquisition unit acquires a second blood flow image without contrast medium with applying a spin labeling pulse by which a region to be tagged is set based on the first blood flow image as a reference image so as to distinguish blood flowing into a desired region.

摘要翻译： 磁共振成像装置包括第一血流图像获取单元和第二血流图像获取单元。 第一血流图像获取单元获取没有造影剂的物体的乳房的第一血流图像。 第二血流图像获取单元获取没有造影剂的第二血流图像，其中应用基于第一血流图像作为参考图像设置要标记的区域的自旋标记脉冲，以便区分流入 所需区域。

公开(公告)号：US20120041299A1

公开(公告)日：2012-02-16

申请号：US13283948

申请日：2011-10-28

申请人： YOSHIMORI KASSAI ,  Mitsue Miyazaki ,  Satoshi Sugiura

发明人： YOSHIMORI KASSAI ,  Mitsue Miyazaki ,  Satoshi Sugiura

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/0456 ,  A61B5/7207 ,  A61B5/7257 ,  A61B5/7285 ,  G01R33/4828 ,  G01R33/5605 ,  G01R33/5607 ,  G01R33/5615 ,  G01R33/5617 ,  G01R33/5635 ,  G01R33/5673

摘要： A magnetic resonance imaging (MRI) system obtains an MR image of an object. The system detects an ECG signal and performs a pulse sequence of RF gradient magnetic fields toward the object. Imaging defined by the pulse sequence is longer in temporal length than one heartbeat. The system further acquires an MR signal from the object in response to performance of the pulse sequence and produces the MR image based on the acquired MR signal. Also possible are: a plurality of divided MT pulses instead of the conventional single MT pulse, an SE-system pulse sequence having a shorter echo train spacing, and the generation of sounds by applying gradient pulses incorporated in an imaging pulse sequence so as to automatically instruct a patient to perform an intermittent breath hold.

摘要翻译： 磁共振成像（MRI）系统获得物体的MR图像。 该系统检测ECG信号，并向对象执行RF梯度磁场的脉冲序列。 由脉冲序列定义的成像在时间长度上比一个心跳长。 系统还响应于脉冲序列的性能从对象获取MR信号，并且基于所获取的MR信号产生MR图像。 还可能的是：多个划分的MT脉冲而不是传统的单个MT脉冲，具有较短回波列间隔的SE系统脉冲序列，以及通过应用结合在成像脉冲序列中的梯度脉冲来产生声音，以便自动地 指示患者进行间歇性呼吸。

公开(公告)号：US08131338B2

公开(公告)日：2012-03-06

申请号：US11819655

申请日：2007-06-28

申请人： Yoshimori Kassai ,  Mitsue Miyazaki ,  Satoshi Sugiura

发明人： Yoshimori Kassai ,  Mitsue Miyazaki ,  Satoshi Sugiura

IPC分类号： A61B5/05

CPC分类号： A61B5/055 ,  A61B5/0456 ,  A61B5/7207 ,  A61B5/7257 ,  A61B5/7285 ,  G01R33/4828 ,  G01R33/5605 ,  G01R33/5607 ,  G01R33/5615 ,  G01R33/5617 ,  G01R33/5635 ,  G01R33/5673

摘要： A magnetic resonance imaging (MRI) system includes an ECG detector for the patient object being imaged and an element for performing an MRI pulse sequence. An imaging unit defined by the pulse sequence is longer in temporal length than one heart beat represented by the ECG signal. An MR signal is acquired from the object in response to the pulse sequence and an MR image based on the acquired MR signal is produced. A plurality of divided MT pulses can be applied instead of the conventional single MT pulse. In this case, an SE-system pulse sequence having a shorter echo train spacing is used, to generate sounds by applying gradient pulses incorporated in an imaging pulse sequence so as to automatically instruct a patient to perform an intermittent breath hold during three-dimensional scanning.

摘要翻译： 磁共振成像（MRI）系统包括用于被成像的患者物体的ECG检测器和用于执行MRI脉冲序列的元件。 由脉冲序列定义的成像单元在时间长度上比由ECG信号表示的一个心跳更长。 响应于脉冲序列从对象获取MR信号，并且产生基于所获取的MR信号的MR图像。 可以应用多个划分的MT脉冲来代替传统的单个MT脉冲。 在这种情况下，使用具有更短回波串间距的SE系统脉冲序列，通过应用结合在成像脉冲序列中的梯度脉冲来产生声音，以便在三维扫描期间自动指示患者执行间歇性呼吸 。

公开(公告)号：US20110148413A1

公开(公告)日：2011-06-23

申请号：US12971517

申请日：2010-12-17

申请人： Mitsue MIYAZAKI ,  Satoshi Sugiura

发明人： Mitsue MIYAZAKI ,  Satoshi Sugiura

IPC分类号： G01R33/44

CPC分类号： G01R33/5635 ,  G01R33/482 ,  G01R33/56316

摘要： A magnetic resonance imaging apparatus according to an embodiment includes a data gathering unit and an image generating unit, the data gathering unit gathers magnetic resonance data in a non-contrast manner by applying a first readout gradient pulse having a zero-order moment of 0 and a second readout gradient pulse having a zero-order moment of 0 and a first-order moment of a value different from a value of a first-order moment of the first readout gradient pulse to a region of interest including a fluid in motion, and the image generating unit periodically arranges first magnetic resonance data read out with the first readout gradient pulse and second magnetic resonance data read out with the second readout gradient pulse in at least one of a phase encoding direction and a slice encoding direction in a k-space to generate k-space data and reconstructs the k-space data to generate an image in which a fluid image and a static part image surrounding the fluid are spatially separated from each other.

摘要翻译： 根据实施例的磁共振成像装置包括数据采集单元和图像生成单元，数据采集单元以非对比度方式收集磁共振数据，通过应用零阶矩为0的第一读出梯度脉冲和 具有零阶矩为0的第二读出梯度脉冲和不同于第一读出梯度脉冲的一阶矩的值与包括运动中的流体的感兴趣区域的值的一阶矩，以及 图像生成单元将第一读出梯度脉冲读出的第一磁共振数据和第二读出梯度脉冲读出的第二磁共振数据周期性地排列在k空间中的相位编码方向和切片编码方向中的至少一个 以产生k空间数据并重建k空间数据以生成其中流体图像和围绕流体的静态部分图像在空间上分离的图像fr 彼此之间。

公开(公告)号：US20070265522A1

公开(公告)日：2007-11-15

申请号：US11819655

申请日：2007-06-28

申请人： Yoshimori Kassai ,  Mitsue Miyazaki ,  Satoshi Sugiura

发明人： Yoshimori Kassai ,  Mitsue Miyazaki ,  Satoshi Sugiura

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/0456 ,  A61B5/7207 ,  A61B5/7257 ,  A61B5/7285 ,  G01R33/4828 ,  G01R33/5605 ,  G01R33/5607 ,  G01R33/5615 ,  G01R33/5617 ,  G01R33/5635 ,  G01R33/5673

摘要： A magnetic resonance imaging (MRI) system includes an ECG detector for the patient object being imaged and an element for performing an MRI pulse sequence. An imaging unit defined by the pulse sequence is longer in temporal length than one heart beat represented by the ECG signal. An MR signal is acquired from the object in response to the pulse sequence and an MR image based on the acquired MR signal is produced. A plurality of divided MT pulses can be applied instead of the conventional single MT pulse. In this case, an SE-system pulse sequence having a shorter echo train spacing is used, to generate sounds by applying gradient pulses incorporated in an imaging pulse sequence so as to automatically instruct a patient to perform an intermittent breath hold during three-dimensional scanning.

摘要翻译： 磁共振成像（MRI）系统包括用于被成像的患者物体的ECG检测器和用于执行MRI脉冲序列的元件。 由脉冲序列定义的成像单元在时间长度上比由ECG信号表示的一个心跳更长。 响应于脉冲序列从对象获取MR信号，并且产生基于获取的MR信号的MR图像。 可以应用多个划分的MT脉冲来代替传统的单个MT脉冲。 在这种情况下，使用具有更短回波串间距的SE系统脉冲序列，通过应用结合在成像脉冲序列中的梯度脉冲来产生声音，以便在三维扫描期间自动指示患者执行间歇性呼吸 。

公开(公告)号：USRE45876E1

公开(公告)日：2016-02-02

申请号：US13590396

申请日：2012-08-21

申请人： Mitsue Miyazaki ,  Satoshi Sugiura

发明人： Mitsue Miyazaki ,  Satoshi Sugiura

IPC分类号： A61B5/055 ,  A61B5/026 ,  A61B5/00 ,  A61B6/00

CPC分类号： A61B5/0263 ,  A61B5/055 ,  A61B5/7257 ,  A61B6/541

摘要： An ECU-prep scan is used to set an optimum time phase in both systole and diastole of the heart. At each of the different time phases, an imaging scan is started to acquire a plurality of sets of echo data. An artery/vein visually separated blood flow image is produced from the echo data. The imaging scan uses a half-Fourier technique, for example. This provides high-quality blood flow images with shorter scan time, without injecting a contrast medium. Additionally, with a readout gradient pulse applied substantially parallel with a direction of slowly flowing blood, a scan is performed in synchronism with an optimally determined cardiac time phase. The readout gradient pulse has a dephasing pulse for enhancing differences in a flow void effect depending on blood flow velocities. This enables slow-speed flows, such as blood flows in the inferior limb, to be depicted without fail.

摘要翻译： 使用ECU准备扫描来设置心脏收缩和舒张期的最佳时间相位。 在每个不同的时间阶段，开始成像扫描以获取多组回波数据。 从回波数据产生视觉上分离的血流图像的动脉/静脉。 成像扫描例如使用半傅里叶技术。 这提供了具有较短扫描时间的高质量血流图像，而不注射造影剂。 另外，利用基本平行于缓慢流动的血液的方向施加的读出梯度脉冲，与最佳确定的心脏时间相位同步进行扫描。 读出梯度脉冲具有去相位脉冲，用于根据血流速度增加流动空隙效应的差异。 这使得能够在不失败的情况下描绘诸如下肢中的血液流的慢速流动。