摘要:
The present invention relates to a patch containing a substrate, a non-crosslinked adhesive layer (A) containing a drug laminated on one surface of the substrate and a crosslinked adhesive layer (B) laminated on the adhesive layer (A). According to the present invention, the percutaneous absorbability of the drug can be improved, and a patch free of problems such as adhesive residue and adhesive bleed can be provided.
摘要:
The present invention relates to a patch containing a substrate, a non-crosslinked adhesive layer (A) containing DMAE or a pharmacologically acceptable salt thereof laminated on one surface of the substrate and a crosslinked adhesive layer (B) laminated on the adhesive layer (A). According to the present invention, the percutaneous absorbability of DMAE or a pharmacologically acceptable salt thereof can be improved, and a patch free of problems such as adhesive residue and adhesive bleed can be provided.
摘要:
A percutaneous absorption type preparation comprising a support and a plaster layer laminated thereon, which composes tulobuterol in a proportion of not less than 5 wt % in a dissolution state and an adhesive. The preparation of the present invention retains the active ingredient, tulobuterol, at a high concentration in a complete dissolution state in the plaster layer. Therefore, it is free of time-course changes in drug releasing property and adhesive property caused by precipitation of drug crystals with the lapse of time. The inventive preparation is superior in percutaneous absorption of the drug, particularly percutaneous absorption rate at the initial stage of the administration; shows superior duration of efficacy by maintaining effective blood concentration for a long time; and is associated with less changes with the lapse of time in adhesive property such as adhesion to the skin.
摘要:
A percutaneous absorption preparation comprising a support and, formed on one side thereof, a plaster layer comprising a pressure-sensitive adhesive and tulobuterol in an amount not lower than its saturation solubility in the pressure-sensitive adhesive, the tulobuterol contained in the plaster layer consisting of dissolved tulobuterol and crystalline tulobuterol with the ratio of the content of the crystalline tulobuterol to that of the dissolved tulobuterol being from 0.1 to 10.
摘要:
Provided is a construction machine. The construction machine is provided with a lower propelling body and an upper slewing body. The upper slewing body has an upper frame, a cab disposed on a left portion or a right portion of the upper frame, and cab mounts. The cab mounts are disposed at lateral ends on each of front and rear portions of the cab respectively, including, on at least one of the front and rear portions, first and second outer-side cab mounts disposed at the outer side of lateral ends of the cab. The first and second outer-side cab mounts are juxtaposed with a small enough distance to receive a rollover load concurrently when the construction machine rolls over toward a side of the cab.
摘要:
A construction machine has a locking mechanism for locking a lower end of a front part of a guard member onto a bracket while allowing a cab to be moved with elastic deformation of an anti-vibration mount. The locking mechanism has a shaft body across the bracket and the guard member vertically movably with the guard member. The shaft body has a stopper to be engaged to an upper frame side to restrict a moving amount of the shaft body to a stroke for shock absorbing. The bracket has a bolt insertion hole for a bolt to fix the bracket and a shaft body insertion hole for the shaft body. The bolt insertion hole is a lateral oblong hole extending in a direction inclined, with respect to the horizontal direction, toward a direction orthogonal to a load acting direction in the lateral rollover.
摘要:
Provided is a construction machine. The construction machine is provided with a lower propelling body and an upper slewing body. The upper slewing body has an upper frame, a cab disposed on a left portion or a right portion of the upper frame, and cab mounts. The cab mounts are disposed at lateral ends on each of front and rear portions of the cab respectively, including, on at least one of the front and rear portions, first and second outer-side cab mounts disposed at the outer side of lateral ends of the cab. The first and second outer-side cab mounts are juxtaposed with a small enough distance to receive a rollover load concurrently when the construction machine rolls over toward a side of the cab.
摘要:
According to one embodiment, a controller for a storage apparatus is disclosed having interfaces connectable to a host system, a first storage apparatus and a second storage apparatus. A data in the first storage apparatus and a data in the second storage apparatus are duplicates. A status table stores the operating state regarding the first storage apparatus and the second storage apparatus, wherein the operating state indicates among writing, reading, or standing by. A monitor monitors the interfaces and set up the operating state into the status table. A buffer memory buffers the data for writing in the first storage apparatus and the second storage apparatus. A command response unit receives the data for writing and write-in request from a host system, and directs the writing of the data to the first storage apparatus and the second storage apparatus while making the buffer memory buffer the received data.
摘要:
A controller is connectable to a host system and a plurality of storage devices. A monitor unit monitors operating status of a plurality of storage devices and sets the operating status of the storage devices in a status table. Upon receiving a write command from the host system, a command responding unit receives write data sent from the host system within a certain period of time after the write command, holds the write data received in a buffer memory, instructs a timer to start counting, sets a write destination for data in the status table, outputs a control signal that gives an instruction to write data to the storage device of the write destination, and returns a write completion response corresponding to the write command to the host system when receiving the deadline notification from the timer.
摘要:
According to an embodiment of the present invention, a mobile communication system comprises a plurality of cellular stations configured to each form areas and a control device configured to connect the cellular stations to a network through communication resources. The control device comprises a construct processing module, a prediction processing module, a secure processing module and an establishment processing module. The construct processing module constructs a database storing hand-off records in time series of a plurality of the mobile terminals. The prediction processing module predicts one or more candidates of cellular stations of connection destinations next to the mobile terminals with reference to the time series of the database before hand-offs are requested. The secure processing module secures channels in the communication resources of the predicted candidates. The establishment processing module establishes communication links via the secured channels among the mobile terminals and the network when hand-off execution is requested.