公开(公告)号：US6117447A

公开(公告)日：2000-09-12

申请号：US203749

申请日：1998-12-02

申请人： Yoshihisa Nakano ,  Mitsuhiko Hori ,  Keiji Yamamoto ,  Saburo Otsuka

发明人： Yoshihisa Nakano ,  Mitsuhiko Hori ,  Keiji Yamamoto ,  Saburo Otsuka

IPC分类号： A61K9/70 ,  A61K31/00 ,  A61K31/045 ,  A61K31/135 ,  A61P11/00 ,  A61P11/08

CPC分类号： A61K9/7053 ,  A61K31/135 ,  A61K9/7061 ,  Y10S514/946 ,  Y10S514/947

摘要： A percutaneous absorption type preparation comprising a support and a plaster layer laminated thereon, which composes tulobuterol in a proportion of not less than 5 wt % in a dissolution state and an adhesive. The preparation of the present invention retains the active ingredient, tulobuterol, at a high concentration in a complete dissolution state in the plaster layer. Therefore, it is free of time-course changes in drug releasing property and adhesive property caused by precipitation of drug crystals with the lapse of time. The inventive preparation is superior in percutaneous absorption of the drug, particularly percutaneous absorption rate at the initial stage of the administration; shows superior duration of efficacy by maintaining effective blood concentration for a long time; and is associated with less changes with the lapse of time in adhesive property such as adhesion to the skin.

摘要翻译： 一种经皮吸收型制剂，其包含层压在其上的支持体和石膏层，其在溶解状态下组成不小于5重量％的比例的丁非特罗和粘合剂。 本发明的制剂在石膏层中以完全溶解状态保持高浓度的活性成分，特鲁替罗。 因此，随着时间的流逝，药物释放性质和药物晶体析出引起的粘合性无时间变化。 本发明的制剂在药物的经皮吸收方面优异，特别是在给药的初始阶段的经皮吸收速率; 通过长期维持有效的血液浓度显示出优异的疗效持续时间; 并且随着粘合性（如粘附于皮肤）随着时间的推移而变化较小。

公开(公告)号：US5639472A

公开(公告)日：1997-06-17

申请号：US419181

申请日：1995-04-10

申请人： Keiji Yamamoto ,  Yoshihisa Nakano ,  Saburo Otsuka

发明人： Keiji Yamamoto ,  Yoshihisa Nakano ,  Saburo Otsuka

IPC分类号： A61K9/70 ,  A61K31/135 ,  A61P11/00 ,  A61P11/08 ,  A61P25/02

CPC分类号： A61K9/7053 ,  A61K31/135 ,  A61K9/7061 ,  A61K9/7076

摘要： A percutaneous absorption preparation comprising a support and, formed on one side thereof, a plaster layer comprising a pressure-sensitive adhesive and tulobuterol in an amount not lower than its saturation solubility in the pressure-sensitive adhesive, the tulobuterol contained in the plaster layer consisting of dissolved tulobuterol and crystalline tulobuterol with the ratio of the content of the crystalline tulobuterol to that of the dissolved tulobuterol being from 0.1 to 10.

摘要翻译： 一种经皮吸收制剂，其包含支持体，并且在其一面上形成包含不低于其在压敏粘合剂中的饱和溶解度的量的压敏粘合剂和十四指酚酸的膏药层，所述膏药层中包含的杜洛特罗组成 溶于十四溴醇和结晶杜洛特罗，结晶叔丁特罗的含量与溶于十四指醇的含量之比为0.1至10。

公开(公告)号：US07964213B2

公开(公告)日：2011-06-21

申请号：US10411822

申请日：2003-04-11

申请人： Mitsuhiko Hori ,  Keiji Yamamoto ,  Kensuke Matsuoka ,  Yoshihisa Nakano

发明人： Mitsuhiko Hori ,  Keiji Yamamoto ,  Kensuke Matsuoka ,  Yoshihisa Nakano

IPC分类号： A61F13/00

CPC分类号： A61K9/7061 ,  Y10T442/2738 ,  Y10T442/674

摘要： The present invention relates to a patch containing a substrate, a non-crosslinked adhesive layer (A) containing a drug laminated on one surface of the substrate and a crosslinked adhesive layer (B) laminated on the adhesive layer (A). According to the present invention, the percutaneous absorbability of the drug can be improved, and a patch free of problems such as adhesive residue and adhesive bleed can be provided.

摘要翻译： 本发明涉及含有基材，含有层叠在基材的一个表面上的药物的非交联粘合剂层（A）和层压在粘合剂层（A）上的交联粘合剂层（B））的贴剂。 根据本发明，可以提高药物的经皮吸收性，并且可以提供没有诸如粘合剂残留和粘合剂渗色的问题的贴剂。

公开(公告)号：US20050214352A1

公开(公告)日：2005-09-29

申请号：US10511061

申请日：2003-04-11

申请人： Mitsuhiko Hori ,  Keiji Yamamoto ,  Kensuke Matsuoka ,  Yoshihisa Nakano ,  Kenjirou Mimomi ,  Masashi Yamada ,  Masaru Otsuka ,  Yasunori Suzuki ,  Akihiro Kawashima

发明人： Mitsuhiko Hori ,  Keiji Yamamoto ,  Kensuke Matsuoka ,  Yoshihisa Nakano ,  Kenjirou Mimomi ,  Masashi Yamada ,  Masaru Otsuka ,  Yasunori Suzuki ,  Akihiro Kawashima

IPC分类号： A61K9/70 ,  A61K31/137 ,  A61K47/10 ,  A61K47/14 ,  A61P9/02 ,  A61K31/138

CPC分类号： A61K9/7061 ,  A61K31/137

摘要： The present invention relates to a patch containing a substrate, a non-crosslinked adhesive layer (A) containing DMAE or a pharmacologically acceptable salt thereof laminated on one surface of the substrate and a crosslinked adhesive layer (B) laminated on the adhesive layer (A). According to the present invention, the percutaneous absorbability of DMAE or a pharmacologically acceptable salt thereof can be improved, and a patch free of problems such as adhesive residue and adhesive bleed can be provided.

摘要翻译： 本发明涉及层叠在基材的一面上的含有基材，含有DMAE的非交联型粘合剂层（A）或其药理学上可接受的盐的贴剂和层叠在粘合剂层（A）上的交联粘合剂层 ）。 根据本发明，可以提高DMAE或其药理学上可接受的盐的经皮吸收性，并且可以提供没有粘合剂残留和粘合剂渗色等问题的贴剂。

公开(公告)号：US08517457B2

公开(公告)日：2013-08-27

申请号：US13540214

申请日：2012-07-02

申请人： Keiji Yamamoto ,  Keiji Yamamoto

发明人： Keiji Yamamoto ,  Keiji Yamamoto

IPC分类号： B60N99/00

CPC分类号： B62D33/0604 ,  B62D33/0633 ,  E02F9/163 ,  E02F9/166

摘要： Provided is a construction machine. The construction machine is provided with a lower propelling body and an upper slewing body. The upper slewing body has an upper frame, a cab disposed on a left portion or a right portion of the upper frame, and cab mounts. The cab mounts are disposed at lateral ends on each of front and rear portions of the cab respectively, including, on at least one of the front and rear portions, first and second outer-side cab mounts disposed at the outer side of lateral ends of the cab. The first and second outer-side cab mounts are juxtaposed with a small enough distance to receive a rollover load concurrently when the construction machine rolls over toward a side of the cab.

摘要翻译： 提供一种施工机械。 施工机械设有下推进体和上回转体。 上部回转体具有上部框架，设置在上部框架的左侧部分或右侧部分上的驾驶室以及驾驶室安装件。 驾驶室安装件分别设置在驾驶室前部和后部各自的侧端部，包括在前部和后部中的至少一个上，设置在外侧端部的外侧的第一和第二外侧驾驶室支架 出租车 第一和第二外侧驾驶室安装件以足够小的距离并置，当施工机器向驾驶室的侧面翻转时，同时接收翻车负载。

公开(公告)号：US20120187721A1

公开(公告)日：2012-07-26

申请号：US13355982

申请日：2012-01-23

申请人： Manabu Nishimura ,  Keiji Yamamoto ,  Keiji Yamamoto ,  Eiji Maeba

发明人： Manabu Nishimura ,  Keiji Yamamoto ,  Keiji Yamamoto ,  Eiji Maeba

IPC分类号： B62D33/06

CPC分类号： E02F9/16

摘要： A construction machine has a locking mechanism for locking a lower end of a front part of a guard member onto a bracket while allowing a cab to be moved with elastic deformation of an anti-vibration mount. The locking mechanism has a shaft body across the bracket and the guard member vertically movably with the guard member. The shaft body has a stopper to be engaged to an upper frame side to restrict a moving amount of the shaft body to a stroke for shock absorbing. The bracket has a bolt insertion hole for a bolt to fix the bracket and a shaft body insertion hole for the shaft body. The bolt insertion hole is a lateral oblong hole extending in a direction inclined, with respect to the horizontal direction, toward a direction orthogonal to a load acting direction in the lateral rollover.

摘要翻译： 施工机械具有用于将防护构件的前部的下端锁定在支架上的锁定机构，同时允许驾驶室通过抗振装置的弹性变形而移动。 锁定机构具有穿过支架的轴体，并且防护件与防护件垂直移动。 轴体具有与上框架侧接合的止动件，以将轴体的移动量限制为用于冲击吸收的行程。 支架具有用于固定支架的螺栓的螺栓插入孔和用于轴体的轴体插入孔。 螺栓插入孔是沿着相对于水平方向倾斜的方向朝向与侧向翻转中的载荷作用方向正交的方向延伸的横向长孔。

公开(公告)号：US20130009423A1

公开(公告)日：2013-01-10

申请号：US13540214

申请日：2012-07-02

申请人： Keiji YAMAMOTO ,  Keiji Yamamoto

发明人： Keiji YAMAMOTO ,  Keiji Yamamoto

IPC分类号： B62D33/06

CPC分类号： B62D33/0604 ,  B62D33/0633 ,  E02F9/163 ,  E02F9/166

摘要： Provided is a construction machine. The construction machine is provided with a lower propelling body and an upper slewing body. The upper slewing body has an upper frame, a cab disposed on a left portion or a right portion of the upper frame, and cab mounts. The cab mounts are disposed at lateral ends on each of front and rear portions of the cab respectively, including, on at least one of the front and rear portions, first and second outer-side cab mounts disposed at the outer side of lateral ends of the cab. The first and second outer-side cab mounts are juxtaposed with a small enough distance to receive a rollover load concurrently when the construction machine rolls over toward a side of the cab.

摘要翻译： 提供一种施工机械。 施工机械设有下推进体和上回转体。 上部回转体具有上部框架，设置在上部框架的左侧部分或右侧部分上的驾驶室以及驾驶室安装件。 驾驶室安装件分别设置在驾驶室前部和后部各自的侧端部，包括在前部和后部中的至少一个上，设置在外侧端部的外侧的第一和第二外侧驾驶室支架 出租车 第一和第二外侧驾驶室安装件以足够小的距离并置，当施工机器向驾驶室的侧面翻转时，同时接收翻车负载。

公开(公告)号：US09141294B2

公开(公告)日：2015-09-22

申请号：US13567925

申请日：2012-08-06

申请人： Yoshiki Namba ,  Hiroyuki Nishikawa ,  Taichi Tashiro ,  Keiji Yamamoto ,  Kohta Nakamura

发明人： Yoshiki Namba ,  Hiroyuki Nishikawa ,  Taichi Tashiro ,  Keiji Yamamoto ,  Kohta Nakamura

IPC分类号： G06F12/00 ,  G06F3/06

CPC分类号： G06F3/0611 ,  G06F3/065 ,  G06F3/0656 ,  G06F3/0688

摘要： According to one embodiment, a controller for a storage apparatus is disclosed having interfaces connectable to a host system, a first storage apparatus and a second storage apparatus. A data in the first storage apparatus and a data in the second storage apparatus are duplicates. A status table stores the operating state regarding the first storage apparatus and the second storage apparatus, wherein the operating state indicates among writing, reading, or standing by. A monitor monitors the interfaces and set up the operating state into the status table. A buffer memory buffers the data for writing in the first storage apparatus and the second storage apparatus. A command response unit receives the data for writing and write-in request from a host system, and directs the writing of the data to the first storage apparatus and the second storage apparatus while making the buffer memory buffer the received data.

摘要翻译： 根据一个实施例，公开了一种用于存储装置的控制器，其具有可连接到主机系统的接口，第一存储装置和第二存储装置。 第一存储装置中的数据和第二存储装置中的数据是重复的。 状态表存储关于第一存储装置和第二存储装置的操作状态，其中操作状态在写入，读取或待机之间指示。 监视器监视接口并将操作状态设置到状态表中。 缓冲存储器缓冲用于在第一存储装置和第二存储装置中写入的数据。 命令响应单元从主机系统接收用于写入和写入请求的数据，并且在使缓冲存储器缓冲接收到的数据的同时，将数据写入到第一存储装置和第二存储装置。

公开(公告)号：US08880832B2

公开(公告)日：2014-11-04

申请号：US13568203

申请日：2012-08-07

申请人： Yoshiki Namba ,  Keiji Yamamoto ,  Taichi Tashiro ,  Hiroyuki Nishikawa ,  Kohta Nakamura

发明人： Yoshiki Namba ,  Keiji Yamamoto ,  Taichi Tashiro ,  Hiroyuki Nishikawa ,  Kohta Nakamura

IPC分类号： G06F12/00 ,  G06F3/06

CPC分类号： G06F3/0611 ,  G06F3/0659 ,  G06F3/0688

摘要： A controller is connectable to a host system and a plurality of storage devices. A monitor unit monitors operating status of a plurality of storage devices and sets the operating status of the storage devices in a status table. Upon receiving a write command from the host system, a command responding unit receives write data sent from the host system within a certain period of time after the write command, holds the write data received in a buffer memory, instructs a timer to start counting, sets a write destination for data in the status table, outputs a control signal that gives an instruction to write data to the storage device of the write destination, and returns a write completion response corresponding to the write command to the host system when receiving the deadline notification from the timer.

摘要翻译： 控制器可连接到主机系统和多个存储设备。 监视器单元监视多个存储设备的操作状态，并将存储设备的操作状态设置在状态表中。 在从主机系统接收到写入命令之后，命令响应单元在写入命令之后的一定时间段内接收从主机系统发送的写入数据，保持接收在缓冲存储器中的写入数据，指示定时器开始计数， 为状态表中的数据设置写目的地，输出向写入目的地的存储装置写入数据的指令的控制信号，并且在接收到期限时向主机系统返回与写命令相对应的写完成响应 定时器通知。

公开(公告)号：US08401557B2

公开(公告)日：2013-03-19

申请号：US12470244

申请日：2009-05-21

申请人： Kazuya Negishi ,  Keiji Yamamoto

发明人： Kazuya Negishi ,  Keiji Yamamoto

IPC分类号： H04W36/00

CPC分类号： H04W36/32 ,  H04W36/38

摘要： According to an embodiment of the present invention, a mobile communication system comprises a plurality of cellular stations configured to each form areas and a control device configured to connect the cellular stations to a network through communication resources. The control device comprises a construct processing module, a prediction processing module, a secure processing module and an establishment processing module. The construct processing module constructs a database storing hand-off records in time series of a plurality of the mobile terminals. The prediction processing module predicts one or more candidates of cellular stations of connection destinations next to the mobile terminals with reference to the time series of the database before hand-offs are requested. The secure processing module secures channels in the communication resources of the predicted candidates. The establishment processing module establishes communication links via the secured channels among the mobile terminals and the network when hand-off execution is requested.

摘要翻译： 根据本发明的一个实施例，一种移动通信系统包括被配置为每个形成区域的多个蜂窝站，以及被配置为通过通信资源将蜂窝站连接到网络的控制设备。 控制装置包括构造处理模块，预测处理模块，安全处理模块和建立处理模块。 构造处理模块以多个移动终端的时间序列构建存储越区切换记录的数据库。 预测处理模块在请求切换之前参考数据库的时间序列来预测移动终端旁边的连接目的地的一个或多个候选的移动站。 安全处理模块确保预测候选者的通信资源中的信道。 建立处理模块在请求切换执行时通过移动终端和网络之间的安全信道建立通信链路。