公开(公告)号：US10323232B2

公开(公告)日：2019-06-18

申请号：US14513656

申请日：2014-10-14

申请人： Mogene LC

发明人： Abhay Singh ,  Himadri Pakrasi ,  Ganesh M. Kishore

IPC分类号： C12N1/20 ,  C12N9/02 ,  C12N9/04 ,  C12N9/88 ,  C12N9/90 ,  C12P7/04 ,  C12P7/16 ,  C12N15/52

摘要： This disclosure relates to the engineering of phototrophic microorganisms for conversion of alkanes into higher-value products. Recombinant phototrophic organisms such as cyanobacteria can be engineered, optionally in a modular format, to express enzymes involved in converting methane to methanol, methanol to formaldehyde, formaldehyde to central metabolic pathway intermediates, and such intermediates to n-butanol.

公开(公告)号：US20150104854A1

公开(公告)日：2015-04-16

申请号：US14513656

申请日：2014-10-14

申请人： Mogene LC

发明人： Abhay Singh ,  Himadri Pakrasi ,  Ganesh M. Kishore

IPC分类号： C12N9/02

CPC分类号： C12N9/0073 ,  C12N1/20 ,  C12N9/0006 ,  C12N9/0071 ,  C12N9/88 ,  C12N9/90 ,  C12N15/52 ,  C12P7/04 ,  C12P7/16 ,  C12Y101/01244 ,  C12Y114/13025 ,  C12Y114/18003 ,  C12Y401/02043 ,  C12Y503/01027 ,  Y02E50/10

摘要： This disclosure relates to the engineering of phototrophic microorganisms for conversion of alkanes into higher-value products. Recombinant phototrophic organisms such as cyanobacteria can be engineered, optionally in a modular format, to express enzymes involved in converting methane to methanol, methanol to formaldehyde, formaldehyde to central metabolic pathway intermediates, and such intermediates to n-butanol.

摘要翻译： 本公开涉及用于将烷烃转化为更高价值产物的光养微生物的工程。 可以任选地以模块化的方式将重组的光生生物如蓝细菌进行改造，以表达将甲烷转化成甲醇，甲醇转化成甲醛，将甲醛转化为中枢代谢途径中间体的酶，将这些中间体转化为正丁醇。