摘要:
A method of operating an industrial plant having processing units that includes a wireless network including a network server, at least one router, and a plurality of workers including a first worker. A first handheld computing device is provided having a wireless transceiver and a processor programmed to implement a location-based service algorithm stored in non-transitory machine readable storage to a first worker. The location-based service algorithm implements obtaining location information that identifies a physical location for the first worker, and adding the location information to wireless transmissions of information by the first worker to others of the plurality of workers or to the network server. The first handheld computing device wirelessly receives server provided plant information that is a function of the physical location, and the first worker performs at least one action guided at least in part by the server provided plant information.
摘要:
Product packaging technique including the conversion of paperboard into boxes and packages in a process that includes layout optimization of printing plates and takes into account vendor specifications, box order types, and printing machine constraints.
摘要:
The present invention relates to an immediate release solid oral dosage form containing 1-aminocyclohexanes, preferably memantine or neramexane, and optionally a pharmaceutically acceptable coating, wherein the active ingredient exhibits dose proportionality and is released at a dissolution rate of more than about 80% within about the first 60 minutes following entry of said form into a use environment. The dosage form is direct compressed and has a hardness within the range of between about 3 and about 40 Kp, exhibits an average Tmax within the range of about 2 to about 8 hours with an active ingredient load within the range of about 2.5 to about 150 mg. The formulation allows for dose-proportional compositions for once daily or b.i.d. dosing, while maintaining a steady average range of Tmax.
摘要:
The present invention relates to an immediate release solid oral dosage form containing 1-aminocyclohexanes, preferably memantine or neramexane, and optionally a pharmaceutically acceptable coating, wherein the active ingredient exhibits dose proportionality and is released at a dissolution rate of more than about 80% within about the first 60 minutes following entry of said form into a use environment. The dosage form is direct compressed and has a hardness within the range of between about 3 and about 40 Kp, exhibits an average Tmax within the range of about 2 to about 8 hours with an active ingredient load within the range of about 2.5 to about 150 mg. The formulation allows for dose-proportional compositions for once daily or b.i.d. dosing, while maintaining a steady average range of Tmax.
摘要翻译:本发明涉及含有1-氨基环己烷,优选美金刚或奈拉美生和任选的药学上可接受的包衣的立即释放的固体口服剂型,其中活性成分表现出剂量比例,并以大于约80%的溶解速率释放 大约在所述表格进入使用环境后的前60分钟。 该剂型是直接压制的并且具有在约3至约40Kp范围内的硬度,在约2至约8小时的范围内显示平均T max max,活性成分负载在 约2.5至约150mg的范围。 该制剂允许剂量比例组合物每天一次或b.i.d。 同时保持T max的稳定平均范围。
摘要:
Integration of clothing performance into production planning, scheduling and execution of papermaking machines yields paper products with consistent acceptable quality with minimum downtime and inventory. Linking the selection and operation of papermaking machines to their respective clothing performances improves clothing life cycle. Selected operating parameters of a papermaking machine and historical clothing data are indicative of the machine's clothing condition. Order scheduling engine identifies manufacturing times for particular grades of product and generates order blocks. Papermaking machines are assigned to execute specific order blocks with provision that each machine completes execution of the assigned orders without any anticipated breakage of the wire or felts.
摘要:
The present invention provides pharmaceutical compositions given once daily containing at least one therapeutically active ingredient selected from the group consisting of memantine and a pharmaceutically acceptable salt of memantine, and a pharmaceutically acceptable polymeric matrix carrier. The dosage forms of the invention sustain the release of the therapeutically active agent from about 4 to about 24 hours when said dosage form is exposed to aqueous solutions. following entry of said form into a use environment, wherein said dosage form has a dissolution rate of more than about 80% after passage of about 6 hours to about 12 hours following said entry into said use environment.
摘要:
The present invention provides immediate release and modified release oral dosage forms. Specifically, the invention provides modified and immediate release pharmaceutical dosage forms containing memantine that exhibit an enhanced release profile and provide reliable absorption. The dosage forms may be used to treat mild, moderate or severe Alzheimer's disease or neuropathic pain.
摘要:
The present invention provides pharmaceutical compositions given once daily containing at least one therapeutically active ingredient selected from the group consisting of memantine and a pharmaceutically acceptable salt of memantine, and a pharmaceutically acceptable polymeric matrix carrier. The dosage forms of the invention sustain the release of the therapeutically active agent from about 4 to about 24 hours when said dosage form is exposed to aqueous solutions. following entry of said form into a use environment, wherein said dosage form has a dissolution rate of more than about 80% after passage of about 6 hours to about 12 hours following said entry into said use environment.
摘要:
Integration of clothing performance into production planning, scheduling and execution of papermaking machines yields paper products with consistent acceptable quality with minimum downtime and inventory. Linking the selection and operation of papermaking machines to their respective clothing performances improves clothing life cycle. Selected operating parameters of a papermaking machine and historical clothing data are indicative of the machine's clothing condition. Order scheduling engine identifies manufacturing times for particular grades of product and generates order blocks. Papermaking machines are assigned to execute specific order blocks with provision that each machine completes execution of the assigned orders without any anticipated breakage of the wire or felts.
摘要:
The present invention relates to an immediate release solid oral dosage form containing 1-aminocyclohexanes, preferably memantine or neramexane, and optionally a pharmaceutically acceptable coating, wherein the active ingredient exhibits dose proportionality and is released at a dissolution rate of more than about 80% within about the first 60 minutes following entry of said form into a use environment. The dosage form is direct compressed and has a hardness within the range of between about 3 and about 40 Kp, exhibits an average Tmax within the range of about 2 to about 8 hours with an active ingredient load within the range of about 2.5 to about 150 mg. The formulation allows for dose-proportional compositions for once daily or b.i.d. dosing, while maintaining a steady average range of Tmax.