公开(公告)号：US20080208323A1

公开(公告)日：2008-08-28

申请号：US12022430

申请日：2008-01-30

申请人： Mohammed S. El-Kurdi ,  Yi Hong ,  Lorenzo Soletti ,  John J. Stankus ,  David A. Vorp ,  William R. Wagner

发明人： Mohammed S. El-Kurdi ,  Yi Hong ,  Lorenzo Soletti ,  John J. Stankus ,  David A. Vorp ,  William R. Wagner

IPC分类号： A61F2/06 ,  D01D5/00

CPC分类号： A61F2/06 ,  A61F2/07 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2240/001 ,  A61F2250/0067 ,  A61L27/18 ,  A61L27/34 ,  A61L27/3625 ,  A61L27/3683 ,  A61L27/3691 ,  A61L27/3804 ,  A61L27/3826 ,  A61L27/507 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/414 ,  A61L2300/604 ,  A61L2430/22 ,  C12N5/0068 ,  C12N2533/40 ,  D01D5/0007 ,  D01D5/0076 ,  D10B2331/10 ,  D10B2401/12 ,  D10B2509/06 ,  C08L67/04

摘要： A tubular tissue graft device is provided comprising a tubular tissue and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.

摘要翻译： 提供了一种管状组织移植装置，其包括管状组织和围绕管状组织的圆周的生物可蚀解聚合物的限制性纤维基质。 基质可以电纺到管状组织上。 在一个实施例中，管状组织来自静脉，例如隐静脉，可用作动脉移植物，例如但不限于冠状动脉旁路手术。 还提供了制备管状移植物的方法，其包括围绕管状组织的周边沉积生物可蚀解聚合物的纤维基质以产生管状组织移植装置。 还提供了一种包括绕管冠状动脉的心脏旁路方法，所述管状组织移植装置包括静脉和围绕静脉周围的生物可蚀解聚合物的限制性纤维基质。

公开(公告)号：US09237945B2

公开(公告)日：2016-01-19

申请号：US12022430

申请日：2008-01-30

申请人： Mohammed S. El-Kurdl ,  Yi Hong ,  Lorenzo Soletti ,  John J. Stankus ,  David A. Vorp ,  William R. Wagner

发明人： Mohammed S. El-Kurdl ,  Yi Hong ,  Lorenzo Soletti ,  John J. Stankus ,  David A. Vorp ,  William R. Wagner

IPC分类号： A61F2/06 ,  D01D5/00 ,  A61L27/38 ,  A61L27/36 ,  A61L27/50 ,  A61L27/34 ,  A61L27/54 ,  A61L27/58 ,  C12N5/00

CPC分类号： A61F2/06 ,  A61F2/07 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2240/001 ,  A61F2250/0067 ,  A61L27/18 ,  A61L27/34 ,  A61L27/3625 ,  A61L27/3683 ,  A61L27/3691 ,  A61L27/3804 ,  A61L27/3826 ,  A61L27/507 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/414 ,  A61L2300/604 ,  A61L2430/22 ,  C12N5/0068 ,  C12N2533/40 ,  D01D5/0007 ,  D01D5/0076 ,  D10B2331/10 ,  D10B2401/12 ,  D10B2509/06 ,  C08L67/04

摘要： A tubular tissue graft device is provided comprising a tubular tissue and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided.

公开(公告)号：US5051122A

公开(公告)日：1991-09-24

申请号：US547369

申请日：1990-07-02

申请人： Walter J. Reese ,  Anastasia Morfesis ,  George T. Salego ,  David A. Vorp

发明人： Walter J. Reese ,  Anastasia Morfesis ,  George T. Salego ,  David A. Vorp

IPC分类号： C03B37/10 ,  B29C70/50 ,  C03B37/14 ,  C03C25/10 ,  C03C25/12 ,  D01G25/00 ,  D04H1/42 ,  D04H3/00 ,  D04H3/12

CPC分类号： D04H3/12 ,  B29C70/508 ,  C03C25/12 ,  Y10T442/69

摘要： The subject matter of this invention relates to a method and apparpatus for making mats of continuous glass fiber strands in which a heated calendering roll and continuous belt are used to compact the mat, expel excess noisture, melt, and/or cure resin previously distributed throughout the glass strand. The resin may be deposited in the mat in the form of a powdered resin or as continuous thread of material that is combined with the remaining strands that form the mat as the glass strands are projected onto the surface of a moving conveyor to form the mat.

摘要翻译： 本发明的主题涉及一种用于制造连续玻璃纤维束的垫的方法和应用，其中使用加热的压延辊和连续带来压紧垫，排出过量的不均匀，熔化和/或固化先前分布在其中的树脂 玻璃股。 树脂可以以粉末状树脂的形式沉积在垫子中，或者作为连续的材料线材，当随着玻璃丝线投射到移动的输送机的表面上以形成垫子时，其与形成垫子的剩余的纱线组合。