利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

32 条记录 (耗时 0.056 秒)

    System and method for large field of view, single cell analysis
    1.
    发明授权
    System and method for large field of view, single cell analysis 有权
    大视野的系统和方法，单细胞分析

    公开(公告)号：US08983581B2

    公开(公告)日：2015-03-17

    申请号：US12469395

    申请日：2009-05-20

    申请人： Moungi G. Bawendi ,  Jorge M. Ferrer ,  W. David Lee ,  Lisa F. Marshall ,  David G. Kirsch

    发明人： Moungi G. Bawendi ,  Jorge M. Ferrer ,  W. David Lee ,  Lisa F. Marshall ,  David G. Kirsch

    IPC分类号： A61B6/00 ,  G06K9/00 ,  A61B5/00

    CPC分类号： A61B5/0071 ,  A61B5/0082 ,  A61B5/0084 ,  A61B5/4848 ,  A61B5/742

    摘要： A method and system for medical imaging employs an excitation source configured to cause an object having a plurality of cells to at least one of emit, reflect, and fluoresce light. An optical receptor is employed that is configured to receive the light from the object. A filter assembly receives the light from the optical receptor and filters the light. An image processor having a field of view (FOV) substantially greater than a diameter of a cell of the object and an analysis resolution substantially matched to the diameter of a cell of the object that receives the filtered light from the filter and analyzes the filtered light corresponding to each cell in the FOV. A feedback system is provided that is configured to provide an indication of a state of each cell in the FOV and a location of a cell in the FOV meeting a predetermined condition.

    摘要翻译： 用于医学成像的方法和系统使用激励源，其被配置为使具有多个单元的对象至少发射，反射和发出荧光。 采用被配置为接收来自物体的光的光学接收器。 过滤器组件接收来自光学接收器的光并过滤光。 具有基本上大于对象的单元的直径的视场（FOV）的图像处理器和与从物体接收滤光器的物体的单元的直径基本匹配的分析分辨率，并分析滤光 对应于FOV中的每个单元格。 提供了一种反馈系统，其被配置为提供FOV中的每个小区的状态的指示以及FOV中的小区的位置满足预定条件。

    System and Method for Large Field of View, Single Cell Analysis
    2.
    发明申请
    System and Method for Large Field of View, Single Cell Analysis 有权
    大视野的系统和方法，单细胞分析

    公开(公告)号：US20090299196A1

    公开(公告)日：2009-12-03

    申请号：US12469395

    申请日：2009-05-20

    申请人： Moungi G. Bawendi ,  Jorge M. Ferrer ,  W. David Lee ,  Lisa F. Marshall ,  David G. Kirsch

    发明人： Moungi G. Bawendi ,  Jorge M. Ferrer ,  W. David Lee ,  Lisa F. Marshall ,  David G. Kirsch

    IPC分类号： A61B6/00

    CPC分类号： A61B5/0071 ,  A61B5/0082 ,  A61B5/0084 ,  A61B5/4848 ,  A61B5/742

    摘要： A method and system for medical imaging employs an excitation source configured to cause an object having a plurality of cells to at least one of emit, reflect, and fluoresce light. An optical receptor is employed that is configured to receive the light from the object. A filter assembly receives the light from the optical receptor and filters the light. An image processor having a field of view (FOV) substantially greater than a diameter of a cell of the object and an analysis resolution substantially matched to the diameter of a cell of the object that receives the filtered light from the filter and analyzes the filtered light corresponding to each cell in the FOV. A feedback system is provided that is configured to provide an indication of a state of each cell in the FOV and a location of a cell in the FOV meeting a predetermined condition.

    摘要翻译： 用于医学成像的方法和系统使用激励源，其被配置为使具有多个单元的对象至少发射，反射和发出荧光。 采用被配置为接收来自物体的光的光学接收器。 过滤器组件接收来自光学接收器的光并过滤光。 具有基本上大于对象的单元的直径的视场（FOV）的图像处理器和与从物体接收滤光器的物体的单元的直径基本匹配的分析分辨率，并分析滤光 对应于FOV中的每个单元格。 提供了一种反馈系统，其被配置为提供FOV中的每个小区的状态的指示以及FOV中的小区的位置满足预定条件。

    NMR device for detection of analytes
    5.
    发明授权
    NMR device for detection of analytes 有权
    用于检测分析物的NMR装置

    公开(公告)号：US08334693B2

    公开(公告)日：2012-12-18

    申请号：US12844672

    申请日：2010-07-27

    申请人： W. David Lee

    发明人： W. David Lee

    IPC分类号： G01V3/00

    CPC分类号： G01R33/302 ,  G01N24/08 ,  G01N24/088 ,  G01R33/281 ,  G01R33/285 ,  G01R33/34007 ,  G01R33/34053 ,  G01R33/34061 ,  G01R33/34069 ,  G01R33/34084 ,  G01R33/341 ,  G01R33/44 ,  G01R33/465 ,  G01R33/5601

    摘要： This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.

    摘要翻译： 本发明一般涉及一种具有一个或多个小孔的检测装置，每个小孔由NMR微线圈包围或非常接近，每个孔含有具有磁性纳米颗粒的液体样品，其在目标分析物存在下自组装或分散 ，从而改变液体样品的NMR测定性质。 该装置可以例如用作用于点护理诊断和/或野外使用的便携式单元，或者该装置可被植入用于连续或间歇地监测患者感兴趣的一种或多种生物物种。

    Laser release process for micromechanical devices
    6.
    发明授权
    Laser release process for micromechanical devices 有权
    微机械装置的激光释放过程

    公开(公告)号：US06538233B1

    公开(公告)日：2003-03-25

    申请号：US09992946

    申请日：2001-11-06

    申请人： W. David Lee ,  Paul A. Ruggerio

    发明人： W. David Lee ,  Paul A. Ruggerio

    IPC分类号： B23K2600

    CPC分类号： B81C1/00484 ,  B23K26/40 ,  B23K2103/50 ,  B81C1/00968 ,  B81C2201/0143 ,  G01P15/0802 ,  G01P2015/0814

    摘要： A method for releasing a structure from contact with a substrate in a micromechanical device includes the step of irradiating the structure with energy having parameters selected to produce a thermal gradient normal to the surface of the structure which causes upward bowing and release of the structure from the substrate. Preferably, the structure is irradiated with laser energy and, more preferably, the structure is irradiated with pulsed laser energy. The temperature gradient creates a strain gradient, due to thermal expansion, which causes the structure to bow upwardly. Support elements react and hold the structure up after the thermal gradient has disappeared.

    摘要翻译： 用于在微机械装置中释放结构与基底接触的方法包括以下步骤：用能量进行照射，所述能量具有选择的参数，以产生与结构表面垂直的热梯度，这导致结构的向上弯曲和释放 基质。 优选地，用激光能量照射该结构，更优选地，用脉冲激光能量照射该结构。 温度梯度由于热膨胀而产生应变梯度，这导致结构向上弯曲。 支撑元件在热梯度消失后反应并保持结构。

    Slide decelerator for a firearm
    7.
    发明授权
    Slide decelerator for a firearm 失效
    滑动减速器为火器

    公开(公告)号：US5060555A

    公开(公告)日：1991-10-29

    申请号：US501476

    申请日：1990-03-30

    申请人： Ghaleb A. Sater ,  Robert L. Constant ,  W. David Lee

    发明人： Ghaleb A. Sater ,  Robert L. Constant ,  W. David Lee

    IPC分类号： F41A3/78

    CPC分类号： F41A3/78

    摘要： Slide decelerator for a firearm has a cylindrical cavity formed in the metallic receiver of the firearm and a deformable mass of elastomeric material is disposed within the cavity. A piston is slidably fitted into the cavity and a rod extends outwardly from the piston for engagement with a depending portion of the slide. The elastomer consists of a cylindrical plug which has a diameter substantially smaller than the inner diameter of the cavity and an axial length approximately equal to that to the length of the cavity. Upon firing, the slide, being moved rearwardly by blow-back of combustion gases, will impact against the rod and elastomeric material will be deformed to thereby absorb the kinetic energy of the slide. As a result, the slide is stopped before impacting against the receiver of the firearm.

    摘要翻译： 用于枪支的滑行减速器具有形成在枪支的金属接收器中的圆柱形空腔，弹性体材料的可变形体设置在腔内。 活塞可滑动地装配到空腔中，并且杆从活塞向外延伸以与滑块的悬垂部分接合。 弹性体由圆柱形塞子组成，其直径基本上小于空腔的内径，并且轴向长度大致等于空腔的长度。 在燃烧时，通过吹回燃烧气体向后移动的滑块将撞击杆，并且弹性体材料将变形，从而吸收滑块的动能。 结果，在撞击枪支的接收器之前，滑块被停止。

    Improved gas oven using flame switching
    8.
    发明授权
    Improved gas oven using flame switching 失效
    改进燃气烤箱采用火焰切换

    公开(公告)号：US4802459A

    公开(公告)日：1989-02-07

    申请号：US135932

    申请日：1987-12-21

    申请人： David H. McFadden ,  W. David Lee

    发明人： David H. McFadden ,  W. David Lee

    IPC分类号： F24C3/08 ,  F24C3/12 ,  F24C3/00

    CPC分类号： F24C3/087 ,  F24C3/128

    摘要： This invention is directed to a method of and apparatus or device for flame switching in order to associate a flame and the energy of the flame with different and distinct energy using systems. The flame switchable gas burning device, when adapted to be mounted or attached within the oven cavity of a gas stove, provides an improved gas stove which can, within the one oven cavity, operate in the broil, bake and self-clean mode without the need for multiple burners or multiple oven cavities and without the need for manually operated baffles or dampers. The flame is caused to be established in a first direction (typically in the broil mode), to being established in a second direction (typically the bake/self-clean mode), that is the flame is switched, by the method of establishing a flame in the first direction, providing a source of fresh air directed toward the source portion of the flame and creating a low pressure zone or a negative pressure field in a region proximate to the source portion of the flame and directed in the second direction thereby causing the flame to switch and be established in the second direction.

    摘要翻译： 本发明涉及一种用于火焰切换的方法和装置或装置，以便使用系统将火焰和火焰的能量与不同和不同的能量相关联。 可燃火焰切换燃气装置在适于安装或安装在燃气灶的炉腔内时提供了一种改进的燃气灶，它可以在一个炉腔内工作在烘烤，烘烤和自清洁模式，而不需要 需要多个燃烧器或多个炉腔，而不需要手动操作的挡板或阻尼器。 导致火焰以第一方向（通常为烘烤模式）建立，以通过建立火焰的方法在第二方向（通常为烘烤/自洁模式）建立，即火焰被切换 在第一方向上形成火焰，提供朝向火焰源部分的新鲜空气源，并且在靠近火焰源部分的区域中产生低压区或负压场，并沿着第二方向引导，从而导致 火焰切换并建立在第二个方向。