公开(公告)号：US20160287374A1

公开(公告)日：2016-10-06

申请号：US15036304

申请日：2014-11-14

Applicant: NEOGRAFT TECHNOLOGIES, INC.

Inventor： Lorenzo SOLETTI ,  Cory LEESON ,  Jon MCGRATH ,  Matthew MANNARINO ,  John SPIRIDIGLIOZZI

IPC: A61F2/07 ,  A61L27/50 ,  A61F2/88 ,  A61L27/34

CPC classification number: A61F2/07 ,  A61F2/04 ,  A61F2/06 ,  A61F2/88 ,  A61F2002/825 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2240/002 ,  A61L27/34 ,  A61L27/507 ,  A61L2420/02 ,  A61L2420/06

Abstract: A graft device for a mammalian patient comprises a tubular conduit and a fiber matrix surrounding the tubular conduit. The fiber matrix can comprise one or more polymers delivered by an electrospinning device. Systems and methods of creating a graft device are also provided.

Abstract translation: 用于哺乳动物患者的移植装置包括管状导管和围绕管状导管的纤维基质。 纤维基质可以包含一种或多种由静电纺丝装置递送的聚合物。 还提供了创建移植装置的系统和方法。

公开(公告)号：US20190263068A1

公开(公告)日：2019-08-29

申请号：US16308216

申请日：2017-06-09

Applicant: NEOGRAFT TECHNOLOGIES, INC.

Inventor： Matthew MANNARINO ,  Jon MCGRATH ,  Cory LEESON ,  Mohammed EL-KURDI ,  Danielle CZARNOWSKI ,  Kermit SANTIAGO ,  J. Christopher FLAHERTY

IPC: B29C64/386 ,  A61M27/00 ,  A61M1/36 ,  B33Y50/00 ,  B33Y80/00 ,  B33Y30/00 ,  B33Y10/00

Abstract: A system for producing a graft device for a patient may comprise: an imaging device configured to produce image data of a tubular conduit; and a processing unit configured to receive the image data from the imaging device. The processing unit may comprise an algorithm configured to process the image data, and produce a construction signal based on the image data. A material delivery device may be configured to receive the construction signal from the processor, and deliver material to produce a 3D covering based on the construction signal. The graft device may comprise the 3D covering positioned about the tubular conduit. Graft devices and methods of producing graft devices may also be provided.

公开(公告)号：US20180368968A1

公开(公告)日：2018-12-27

申请号：US16063503

申请日：2016-12-20

Applicant: NEOGRAFT TECHNOLOGIES, INC.

Inventor： Cory LEESON ,  Matthew MANNARINO ,  Mohammed EL-KURDI ,  Jon MCGRATH

IPC: A61F2/06 ,  A61M1/36 ,  A61L27/50 ,  A61L27/16 ,  A61L27/18 ,  A61L27/36 ,  D01D5/00 ,  D01D13/02

Abstract: Provided are systems for applying a polymer fiber matrix to a tubular conduit to create a graft device. The system comprises a polymer solution comprising at least one polymer and at least one solvent; a polymer delivery assembly constructed and arranged to receive the polymer solution and to deliver the polymer fiber matrix to the tubular conduit; a rotating assembly constructed and arranged to rotate at least one of the tubular conduit or the polymer delivery assembly; and a controller constructed and arranged to control the polymer delivery assembly and the rotating assembly. The system is constructed and arranged to reduce the amount of the solvent in the graft device. Methods of applying a polymer fiber matrix with reduced solvent are also provided.