公开(公告)号：US20160101081A1

公开(公告)日：2016-04-14

申请号：US14879600

申请日：2015-10-09

Applicant: NESTEC SA

Inventor： Yuanlong Pan ,  Janet R. Jackson

IPC: A61K31/23 ,  A23K1/16 ,  A61K45/06

CPC classification number: A61K31/23 ,  A23K20/147 ,  A23K20/158 ,  A23K20/163 ,  A23K20/174 ,  A23K50/42 ,  A23K50/45 ,  A23V2002/00 ,  A61K45/06 ,  A23V2200/302 ,  A23V2250/1944

Abstract: The present invention provides a method for increasing mobility or activity in an animal or treating or preventing frailty in an animal, comprising identifying an animal with decreased mobility or activity or having frailty and administering a composition comprising one or more medium chain triglycerides (MCTs) to the animal in a therapeutically amount effective for increasing mobility or activity in the animal or treating frailty in the animal. Additionally, a food composition can comprise about 15% to about 50% protein, about 5% to about 40% fat, about 5% to about 50% carbohydrate, and about 1% to about 40% of one or more medium chain triglycerides (MCTs); wherein the composition has a moisture content of about 5% to about 20% and the MCTs are present in a therapeutically amount effective for increasing mobility or activity in the animal or treating frailty in the animal.

Abstract translation: 本发明提供一种用于增加动物中的迁移率或活性或治疗或预防动物体内虚弱的方法，其包括鉴定具有降低的活动性或具有虚弱的动物，或将包含一种或多种中链甘油三酯（MCT）的组合物施用于 该动物治疗量对于增加动物的运动或活动或治疗动物体内的虚弱有效。 另外，食物组合物可以包含约15％至约50％的蛋白质，约5％至约40％的脂肪，约5％至约50％的碳水化合物和约1％至约40％的一种或多种中链甘油三酯（ MCT）; 其中所述组合物的水分含量为约5％至约20％，并且所述MCT以治疗量存在，所述治疗量对于增加动物中的迁移率或活性或治疗动物体内的虚弱有效。

公开(公告)号：US20140134747A1

公开(公告)日：2014-05-15

申请号：US14076364

申请日：2013-11-11

Applicant: NESTEC SA

Inventor： Yuanlong Pan ,  Steven S. Hannah ,  Peichuan Sun ,  Janet R. Jackson

IPC: G01N33/64

CPC classification number: G01N33/64 ,  Y10T436/201666

Abstract: The invention provides methods for determining if an animal's metabolism has been shifted to ketogenic status by collecting a first urine sample from the animal when the animal's metabolism is not in a ketogenic status; collecting a second urine sample from the animal when the animal's metabolism is possibly in a ketogenic status; analyzing the first urine sample and the second urine sample for beta-hydroxy butyrate; and determining that the animal's metabolism has been shifted to ketogenic status if the concentration of beta-hydroxy butyrate in the second urine sample exceeds the concentration of beta-hydroxy butyrate in the first urine sample by ten percent (10%) or more.

Abstract translation: 本发明提供了当动物的代谢不是酮生成状态时，通过从动物收集第一尿液样品来确定动物的代谢是否已转移到致酮状态的方法; 当动物的代谢可能处于酮症状态时，从动物收集第二个尿样; 分析第一个尿液样品和第二个尿液样品的β-羟基丁酸盐; 如果第二次尿液样品中β-羟基丁酸盐的浓度超过第一个尿液样品中β-羟基丁酸的浓度10％（10％）以上，则确定动物的代谢已转移到酮症状态。