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公开(公告)号：US12006314B2
公开(公告)日：2024-06-11
申请号：US17735011
申请日：2022-05-02
Applicant: Nuvation Bio Inc.
Inventor： David Hung , Jayakanth Kankanala , Christopher Paul Miller , Jeremy David Pettigrew , Son Minh Pham , Ihab S. Darwish
IPC: C07D471/04 , C07D403/10 , C07D403/14 , C07D413/14 , C07D417/14
CPC classification number: C07D471/04 , C07D403/10 , C07D403/14 , C07D413/14 , C07D417/14
Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, such as a compound of Formula I:
or a tautomer, stereoisomer, mixture of stereoisomers, hydrate, solvate, isotopically enriched analog, or pharmaceutically acceptable salt thereof, to products containing the same, as well as to methods of their use and preparation.-
公开(公告)号：US20220213122A1
公开(公告)日：2022-07-07
申请号：US17457397
申请日：2021-12-02
Applicant: NUVATION BIO INC.
Inventor： Son Minh PHAM , Sarvajit Chakravarty , Jayakanth Kankanala , Jiyun Chen , Anjan Kumar Nayak , Anup Barde
IPC: C07D513/04 , A61P35/00 , C07D213/89 , C07D471/04 , C07D239/36 , C07D237/22 , C07D239/90 , C07D417/12 , C07D401/12 , C07D409/12 , C07D411/10 , C07D491/048 , C07D495/04 , C07D498/04
Abstract: Novel bromodomain and extraterminal domain (BET) inhibitors and to therapeutic methods of treating conditions and diseases using these novel BET inhibitors are provided.
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公开(公告)号：US20210214316A1
公开(公告)日：2021-07-15
申请号：US17096743
申请日：2020-11-12
Applicant: Nuvation Bio Inc.
Inventor： Son Minh Pham , Jayakanth Kankanala , Jeremy Pettigrew , Christopher Paul Miller
IPC: C07D237/32
Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.
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公开(公告)号：US11034669B2
公开(公告)日：2021-06-15
申请号：US16698490
申请日：2019-11-27
Applicant: Nuvation Bio Inc.
Inventor： Sarvajit Chakravarty , Son Minh Pham , Jiyun Chen , Jayakanth Kankanala , Jeremy D. Pettigrew , Anjan Kumar Nayak , Anup Barde , Brahmam Pujala
IPC: C07D417/12 , A61K31/427 , C07D401/12 , A61P35/04 , C07D401/14 , C07D403/12 , C07D417/14 , C07D471/04 , A61K9/00 , A61K45/06
Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.
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公开(公告)号：US12208141B2
公开(公告)日：2025-01-28
申请号：US18472993
申请日：2023-09-22
Applicant: Nuvation Bio Inc.
Inventor： David Hung , Son Minh Pham , Sarvajit Chakravarty , Jiyun Chen , Jayakanth Kankanala , Jeremy D. Pettigrew , Anup Barde , Anjan Kumar Nayak
IPC: A61K47/55 , A61K9/00 , A61K31/438 , A61K31/4745 , A61K31/498 , A61K31/4985 , A61K31/502 , A61K31/5025 , A61K31/519 , A61K31/52 , A61K31/5377 , A61K31/55 , A61K47/68 , C07D401/12 , C07D401/14 , C07D403/12 , C07D471/04 , C07D471/06
Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.
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Patent Agency Ranking
公开(公告)号：US11254670B2
公开(公告)日：2022-02-22
申请号：US16746769
申请日：2020-01-17
Applicant: NUVATION BIO INC.
Inventor： Son Minh Pham , Jayakanth Kankanala , Pradeep S. Jadhavar , Baban Mohan Mulik , Farha Khan , Sreekanth A. Ramachandran
IPC: C07D471/04 , C07D519/00 , A61P35/04
Abstract: 1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.
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公开(公告)号：US11174252B2
公开(公告)日：2021-11-16
申请号：US16277355
申请日：2019-02-15
Applicant: NUVATION BIO INC.
Inventor： Son Minh Pham , Sarvajit Chakravarty , Jayakanth Kankanala , Brahmam Pujala , Amit Shete , Bhawana Bhatt , Anil Kumar Agarwal , Sanjeev Soni , Jiyun Chen
IPC: C07D413/14 , A61P35/00
Abstract: Heterocyclic compounds of Formula (J) as CDK4 or CDK6 or other CDK inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.
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公开(公告)号：US11834458B2
公开(公告)日：2023-12-05
申请号：US17701425
申请日：2022-03-22
Applicant: Nuvation Bio Inc.
Inventor： David Hung , Jayakanth Kankanala , Christopher Paul Miller , Jeremy David Pettigrew , Son Minh Pham , Ihab S. Darwish
IPC: C07D491/22 , A61K31/4745 , C07D471/14
CPC classification number: C07D491/22 , C07D471/14
Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.
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公开(公告)号：US11826430B2
公开(公告)日：2023-11-28
申请号：US15931495
申请日：2020-05-13
Applicant: Nuvation Bio Inc.
Inventor： David Hung , Son Minh Pham , Sarvajit Chakravarty , Jiyun Chen , Jayakanth Kankanala , Jeremy D. Pettigrew , Anup Barde , Anjan Kumar Nayak
IPC: C07D471/04 , C07D471/06 , C07D401/12 , A61K47/55 , A61K31/4745 , C07D401/14 , C07D403/12 , A61K9/00 , A61K47/68 , A61K31/502 , A61K31/55 , A61K31/5377 , A61K31/498 , A61K31/52 , A61K31/5025 , A61K31/438 , A61K31/519 , A61K31/4985
CPC classification number: A61K47/55 , A61K9/0053 , A61K31/438 , A61K31/4745 , A61K31/498 , A61K31/4985 , A61K31/502 , A61K31/5025 , A61K31/519 , A61K31/52 , A61K31/5377 , A61K31/55 , A61K47/6877 , C07D401/12 , C07D401/14 , C07D403/12 , C07D471/04 , C07D471/06
Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.
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公开(公告)号：US20220380364A1
公开(公告)日：2022-12-01
申请号：US17735011
申请日：2022-05-02
Applicant: Nuvation Bio Inc.
Inventor： David Hung , Jayakanth Kankanala , Christopher Paul Miller , Jeremy David Pettigrew , Son Minh Pham
IPC: C07D471/04 , C07D403/10 , C07D413/14 , C07D417/14 , C07D403/14
Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.
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