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1.发明授权Controlled-release, drug-delivery tableted composition including a complex between poly(maleic diacid-alkyl vinyl ether) and polyvinylpyrrolidone 有权控制释放，药物递送成片组合物，包括聚（马来酸二酸 - 烷基乙烯基醚）和聚乙烯吡咯烷酮
公开(公告)号：US6129931A
公开(公告)日：2000-10-10
申请号：US146422
申请日：1998-09-03
CPC分类号： A61K9/2027 , A61K9/2009
摘要： A pH-dependent, controlled-release, drug delivery composition is described herein which includes:(a) a complex between poly(maleic diacid-alkyl vinyl ether) and polyvinylpyrrolidone, or their equivalents, and(b) an effective amount of a pharmaceutical medicament.
摘要翻译： 本文描述了pH依赖性，控释药物递送组合物，其包括：（a）聚（马来酸二酸 - 烷基乙烯基醚）和聚乙烯吡咯烷酮或其等同物之间的复合物，和（b）有效量的药物 药物。
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2.发明授权Controlled release, drug-delivery tableted composition including a polymer of a vinyl amide, (meth)acrylic acid, a long chain alkyl (meth)acrylate and a lower alkyl (meth)acrylate 失效（甲基）丙烯酸，（甲基）丙烯酸长链烷基酯和（甲基）丙烯酸低级烷基酯的控释药物递送成片组合物
公开(公告)号：US5919484A
公开(公告)日：1999-07-06
申请号：US7409
申请日：1998-01-15
CPC分类号： A61K9/2027
摘要： A controlled release, drug-delivery tableted composition comprising, by weight, an uncrosslinked or crosslinked polymer of (a) about 5-40% of a vinyl amide, (b) about 10-70% of (meth)acrylic acid, (c) about 5-40% of a long chain alkyl (meth)acrylate or acrylamide, and (d) about 0-60% of a lower alkyl (meth)acrylate, and a pharmaceutical medicament.
摘要翻译： （a）约5-40％的乙烯基酰胺的未交联或交联的聚合物，（b）约10-70％的（甲基）丙烯酸，（c）的控释药物递送的成片组合物 ）约5-40％的长链烷基（甲基）丙烯酸酯或丙烯酰胺，和（d）约0-60％的（甲基）丙烯酸低级烷基酯和药物。
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公开(公告)号：US20050196436A1
公开(公告)日：2005-09-08
申请号：US10791478
申请日：2004-03-02
CPC分类号： A61K9/4816
摘要： The present invention relates to a method of producing a film forming blend of different acyl gellan gums with starch having similar textural and functional properties compared to gelatin. Films prepared using such blends have a high modulus and excellent strength and elongation. The present invention also relates to soft capsules prepared using such blends or films, which have good sealability.
摘要翻译： 本发明涉及与明胶相比，制备不同酰基绞兰胶与淀粉的成膜混合物的方法，该淀粉具有相似的结构和功能特性。 使用这种共混物制备的膜具有高模量和优异的强度和伸长率。 本发明还涉及使用这种具有良好密封性的共混物或薄膜制备的软胶囊。
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4.发明授权Co-processing method for making a free-flowing compressible powder and tablet therefrom 失效用于制造自由流动的可压缩粉末和片剂的协同处理方法
公开(公告)号：US5560927A
公开(公告)日：1996-10-01
申请号：US508361
申请日：1995-07-28
申请人： Anil Menon , Timothy Gillece , Sibu Chakrabarti
发明人： Anil Menon , Timothy Gillece , Sibu Chakrabarti
CPC分类号： B01J2/02 , A61K9/2059 , A61K9/2095 , A61K9/2027
摘要： A process for making a free-flowing, compressible powder by spraying a selected amount of an aqueous solution of polyvinylpyrrolidone onto a fluid bed containing a predetermined admixture of starch and polyvinylpyrrolidone therein, and drying. An active-containing tablet then is provided by adding an active material, optionally with a lubricant, to such powder, and compressing the admixture into a commercially acceptable tablet.
摘要翻译： 通过将选定量的聚乙烯吡咯烷酮水溶液喷洒到含有预定的淀粉和聚乙烯吡咯烷酮混合物的流化床上并干燥来制备自由流动的可压缩粉末的方法。 然后通过将任选具有润滑剂的活性材料添加到这种粉末中并将该混合物压制成商业上可接受的片剂来提供含活性物质的片剂。
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公开(公告)号：US5660823A
公开(公告)日：1997-08-26
申请号：US662408
申请日：1996-06-12
申请人： Sibu Chakrabarti , Anil Menon
发明人： Sibu Chakrabarti , Anil Menon
IPC分类号： A01N59/12 , A61K8/00 , A61K8/19 , A61K8/20 , A61K8/34 , A61K8/72 , A61K8/81 , A61K8/86 , A61K9/70 , A61K31/00 , A61K31/79 , A61K38/00 , A61K47/30 , A61K47/48 , A61L26/00 , A61P17/00 , A61Q19/00 , A61K47/32 , A61K33/18
CPC分类号： A61L26/0076 , A01N59/12 , A61K47/48176 , A61K9/7015 , A61L26/0066 , A61L2300/202 , A61L2300/404
摘要： This invention relates to a fast drying iodine complex solution having film forming capability and skin substantivity which solution consists essentially of:(a) between 1 and 25 wt % polyvinyl pyrrolidone/iodine (PVP/I) complex;(b) between 5 and 15 wt % vinyl pyrrolidone/vinyl acetate copolymer (PVP/VA);(c) between 0.5 and 1.5 wt % non-plasticizing polyethylene glycol (PEG);(d) between 35 and 75 wt % C.sub.1 to C.sub.4 alkanol;(e) between 12 and 35 wt % deionized water and(f) between 0 and 2.5 wt % of 1-vinyl-3-(E)-ethylidene pyrrolidone, based on total composition.The invention also relates to the method of preparing the film forming solution which has a drying time of less than 5 minutes.
摘要翻译： 本发明涉及一种具有成膜能力和皮肤亲和力的快速干燥碘络合物溶液，该溶液基本上由以下组成：（a）1至25重量％的聚乙烯吡咯烷酮/碘（PVP / I）络合物; （b）5至15wt％乙烯基吡咯烷酮/乙酸乙烯酯共聚物（PVP / VA）; （c）0.5-1.5wt％的非增塑聚乙二醇（PEG）; （d）35至75重量％的C1至C4链烷醇; （e）12至35重量％的去离子水和（f）基于总组合物的0-5重量％的1-乙烯基-3-（E） - 亚乙基吡咯烷酮。 本发明还涉及制备干燥时间小于5分钟的成膜溶液的方法。
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公开(公告)号：US07494667B2
公开(公告)日：2009-02-24
申请号：US10791478
申请日：2004-03-02
CPC分类号： A61K9/4816
摘要： The present invention relates to a method of producing a film forming blend of different acyl gellan gums with starch having similar textural and functional properties compared to gelatin. Films prepared using such blends have a high modulus and excellent strength and elongation. The present invention also relates to soft capsules prepared using such blends or films, which have good sealability.
摘要翻译： 本发明涉及与明胶相比，制备不同酰基绞兰胶与淀粉的成膜混合物的方法，该淀粉具有相似的结构和功能特性。 使用这种共混物制备的膜具有高模量和优异的强度和伸长率。 本发明还涉及使用这种具有良好密封性的共混物或薄膜制备的软胶囊。
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