公开(公告)号：US20050171703A1

公开(公告)日：2005-08-04

申请号：US11036780

申请日：2005-01-14

申请人： Neil Goldfine ,  Darrell Schlicker ,  Vladimir Zilberstein ,  Andrew Washabaugh ,  Volker Weiss ,  Christopher Craven ,  Ian Shay ,  David Grundy ,  Karen Walrath ,  Robert Lyons

发明人： Neil Goldfine ,  Darrell Schlicker ,  Vladimir Zilberstein ,  Andrew Washabaugh ,  Volker Weiss ,  Christopher Craven ,  Ian Shay ,  David Grundy ,  Karen Walrath ,  Robert Lyons

IPC分类号： G01N27/90 ,  G06F19/00

CPC分类号： G01N27/9013

摘要： Methods are described for assessing material condition. These methods include the use of multiple source fields for interrogating and loading of a multicomponent test material. Source fields include electric, magnetic, thermal, and acoustic fields. The loading field preferentially changes the material properties of a component of the test material, which allows the properties of the component materials to be separated. Methods are also described for monitoring changes in material state using separate drive and sense electrodes with some of the electrodes positioned on a hidden or even embedded material surface. Statistical characterization of the material condition is performed with sensor arrays that provide multiple responses for the material condition during loading. The responses can be combined into a statistical population that permits tracking with respect to loading history. Methods are also described for measuring the stress in the material by independently estimating effective electrical properties, such as magnetic permeability or electrical conductivity, using layered models or predetermined spatial distributions with depth that are then correlated with the stress.

摘要翻译： 描述了评估材料状况的方法。 这些方法包括使用多个源字段来询问和加载多组分测试材料。 源场包括电，磁，热和声场。 加载场优先改变测试材料的组分的材料性质，这允许分离组分材料的性质。 还描述了用于使用单独的驱动和感测电极来监测材料状态的变化的方法，其中一些电极位于隐藏的或甚至嵌入的材料表面上。 使用传感器阵列进行材料状态的统计表征，这些传感器阵列在加载期间为材料状态提供多个响应。 响应可以组合成允许跟踪加载历史的统计数据。 还描述了通过使用分层模型或具有深度的预定空间分布独立地估计有效电特性（例如磁导率或导电性）来测量材料中的应力的方法，然后与应力相关联。

公开(公告)号：US20070227255A1

公开(公告)日：2007-10-04

申请号：US11698296

申请日：2007-01-25

申请人： Neil Goldfine ,  Vladimir Zilberstein ,  David Grundy ,  Andrew Washabaugh ,  Darrell Schlicker ,  Ian Shay ,  Robert Lyons ,  Christopher Craven ,  Christopher Root ,  Mark Windoloski ,  Volker Weiss

发明人： Neil Goldfine ,  Vladimir Zilberstein ,  David Grundy ,  Andrew Washabaugh ,  Darrell Schlicker ,  Ian Shay ,  Robert Lyons ,  Christopher Craven ,  Christopher Root ,  Mark Windoloski ,  Volker Weiss

IPC分类号： G01L1/12

CPC分类号： G01N27/902 ,  G01N27/023 ,  G01N27/24 ,  G01N27/904 ,  G01N27/9046 ,  G01N27/9053

摘要： Observability of damage precursor, damage and usage states, or event occurrence may be enhanced by modifying component materials to include self-monitoring materials or by processing test material to alter the surface properties. The properties of the self monitoring materials, such as magnetic permeability or electrical conductivity, are monitored with electromagnetic sensors and provide greater property variations with component condition than the original component material. Processing includes shot peening or laser welding.

公开(公告)号：US20050083032A1

公开(公告)日：2005-04-21

申请号：US10937105

申请日：2004-09-08

申请人： Neil Goldfine ,  Vladimir Zilberstein ,  David Grundy ,  Andrew Washabaugh ,  Darrell Schlicker ,  Ian Shay ,  Robert Lyons ,  Christopher Craven ,  Christopher Root ,  Mark Windoloski ,  Volker Weiss

发明人： Neil Goldfine ,  Vladimir Zilberstein ,  David Grundy ,  Andrew Washabaugh ,  Darrell Schlicker ,  Ian Shay ,  Robert Lyons ,  Christopher Craven ,  Christopher Root ,  Mark Windoloski ,  Volker Weiss

IPC分类号： G01N27/00 ,  G01N27/02 ,  G01N27/24 ,  G01N27/90

CPC分类号： G01N27/902 ,  G01N27/023 ,  G01N27/24 ,  G01N27/904 ,  G01N27/9046 ,  G01N27/9053

摘要： Observability of damage precursor, damage and usage states, or event occurrence may be enhanced by modifying component materials to include self-monitoring materials or by processing test material to alter the surface properties. The properties of the self monitoring materials, such as magnetic permeability or electrical conductivity, are monitored with electromagnetic sensors and provide greater property variations with component condition than the original component material. Processing includes shot peening or laser welding.

摘要翻译： 通过修改组分材料以包括自我监测材料或通过加工测试材料以改变表面性质，可以增强损伤前体，损坏和使用状态或事件发生的可观察性。 使用电磁传感器监测自我监测材料的特性，例如磁导率或电导率，并且与原始组件材料相比，可提供比组件条件更大的性能变化。 处理包括喷丸硬化或激光焊接。

公开(公告)号：US20070114993A1

公开(公告)日：2007-05-24

申请号：US11292146

申请日：2005-11-30

申请人： Neil Goldfine ,  Ian Shay ,  Darrell Schlicker ,  Andrew Washabaugh ,  David Grundy ,  Robert Lyons ,  Vladimir Zilberstein ,  Vladimir Tsukernik

发明人： Neil Goldfine ,  Ian Shay ,  Darrell Schlicker ,  Andrew Washabaugh ,  David Grundy ,  Robert Lyons ,  Vladimir Zilberstein ,  Vladimir Tsukernik

IPC分类号： G01R33/12

CPC分类号： G01N27/9013

摘要： Described are methods for monitoring of stresses and other material properties. These methods use measurements of effective electrical properties, such as magnetic permeability and electrical conductivity, to infer the state of the test material, such as the stress, temperature, or overload condition. The sensors, which can be single element sensors or sensor arrays, can be used to periodically inspect selected locations, mounted to the test material, or scanned over the test material to generate two-dimensional images of the material properties. Magnetic field or eddy current based inductive and giant magnetoresistive sensors may be used on magnetizable and/or conducting materials, while capacitive sensors can be used for dielectric materials. Methods are also described for the use of state-sensitive layers to determine the state of materials of interest. These methods allow the weight of articles, such as aircraft, to be determined.

摘要翻译： 描述了用于监测应力和其他材料性质的方法。 这些方法使用诸如磁导率和电导率之类的有效电性能的测量来推断测试材料的状态，例如应力，温度或过载条件。 可以使用可以是单元件传感器或传感器阵列的传感器来周期性地检查安装到测试材料上的选定位置，或者在测试材料上扫描以产生材料特性的二维图像。 基于磁场或涡电流的感应和巨磁阻传感器可用于可磁化和/或导电材料，而电容传感器可用于介电材料。 还描述了使用状态敏感层来确定感兴趣的材料的状态的方法。 这些方法允许确定诸如飞机的物品的重量。

公开(公告)号：US20050127908A1

公开(公告)日：2005-06-16

申请号：US10963482

申请日：2004-10-12

申请人： Darrell Schlicker ,  Neil Goldfine ,  David Grundy ,  Robert Lyons ,  Vladimir Zilberstein ,  Andrew Washabaugh ,  Vladimir Tsukernik ,  Mark Windoloski ,  Ian Shay

发明人： Darrell Schlicker ,  Neil Goldfine ,  David Grundy ,  Robert Lyons ,  Vladimir Zilberstein ,  Andrew Washabaugh ,  Vladimir Tsukernik ,  Mark Windoloski ,  Ian Shay

IPC分类号： G01N27/02 ,  G01N27/82

CPC分类号： G01N27/023 ,  G01N27/9046

摘要： Methods and apparatus are described for absolute electrical property measurement of materials. This is accomplished with magnetic and electric field based sensors and sensor array geometries that can be modeled accurately and with impedance instrumentation that permits accurate measurements of the in-phase and quadrature phase signal components. A dithering calibration method is also described which allows the measurement to account for background material noise variations. Methods are also described for accounting for noise factors in sensor design and selection of the optimal operating conditions which can minimize the error bounds for material property estimates. Example application of these methods to automated engine disk slot inspection and assessment of the mechanical condition of dielectric materials are presented.

摘要翻译： 对材料的绝对电气性能测量方法和设备进行了描述。 这是通过基于磁场和电场的传感器和传感器阵列几何形状来实现的，其可以被精确地建模并且具有允许精确测量同相和正交相位信号分量的阻抗测量。 还描述了抖动校准方法，其允许测量考虑背景材料噪声变化。 还描述了用于考虑传感器设计中的噪声因子和选择可以最小化材料性能估计的误差界限的最佳操作条件的方法。 介绍了将这些方法应用于自动化引擎盘槽检查和评估介电材料的机械状态。

公开(公告)号：US20050088172A1

公开(公告)日：2005-04-28

申请号：US10934103

申请日：2004-09-03

申请人： Neil Goldfine ,  Vladimir Zilberstein ,  Darrell Schlicker ,  David Grundy ,  Ian Shay ,  Robert Lyons ,  Andrew Washabaugh

发明人： Neil Goldfine ,  Vladimir Zilberstein ,  Darrell Schlicker ,  David Grundy ,  Ian Shay ,  Robert Lyons ,  Andrew Washabaugh

IPC分类号： G01N27/90 ,  G01N27/72

CPC分类号： G01N27/9046

摘要： Quasistatic sensor responses may be converted into multiple model parameters to characterize hidden properties of a material. Methods of conversion use databases of responses and, in some cases, databases that include derivatives of the responses, to estimate at least three unknown model parameters, such as the electrical conductivity, magnetic permeability, dielectric permittivity, thermal conductivity, and/or layer thickness. These parameter responses are then used to obtain a quantitative estimate of a property of a hidden feature, such as corrosion loss layer thicknesses, inclusion size and depth, or stress variation. The sensors can be single element sensors or sensor arrays and impose an interrogation electric, magnetic, or thermal field.

摘要翻译： 准静态传感器响应可以转换成多个模型参数来表征材料的隐藏属性。 转换方法使用响应数据库，在某些情况下，包括响应的衍生物的数据库，估计至少三个未知模型参数，如电导率，磁导率，介电常数，导热系数和/或层厚度 。 然后使用这些参数响应来获得隐藏特征的性质的定量估计，例如腐蚀损失层厚度，夹杂物尺寸和深度或应力变化。 这些传感器可以是单元件传感器或传感器阵列，并且会产生询问电磁场或热场。

公开(公告)号：US20060244443A1

公开(公告)日：2006-11-02

申请号：US11343741

申请日：2006-01-30

申请人： Neil Goldfine ,  Andrew Washabaugh ,  Yanko Sheiretov ,  Darrell Schlicker ,  Robert Lyons ,  Mark Windoloski ,  Christopher Craven ,  Vladimir Tsukernik ,  David Grundy

发明人： Neil Goldfine ,  Andrew Washabaugh ,  Yanko Sheiretov ,  Darrell Schlicker ,  Robert Lyons ,  Mark Windoloski ,  Christopher Craven ,  Vladimir Tsukernik ,  David Grundy

IPC分类号： G01N27/72

CPC分类号： G01N27/9046

摘要： Eddy current sensors and sensor arrays are used for process quality and material condition assessment of conducting materials. In an embodiment, changes in spatially registered high resolution images taken before and after cold work processing reflect the quality of the process, such as intensity and coverage. These images also permit the suppression or removal of local outlier variations. Anisotropy in a material property, such as magnetic permeability or electrical conductivity, can be intentionally introduced and used to assess material condition resulting from an operation, such as a cold work or heat treatment. The anisotropy is determined by sensors that provide directional property measurements. The sensor directionality arises from constructs that use a linear conducting drive segment to impose the magnetic field in a test material. Maintaining the orientation of this drive segment, and associated sense elements, relative to a material edge provides enhanced sensitivity for crack detection at edges.

摘要翻译： 涡流传感器和传感器阵列用于导电材料的工艺质量和材料状况评估。 在一个实施例中，在冷加工处理之前和之后拍摄的空间注册的高分辨率图像的变化反映了过程的质量，例如强度和覆盖。 这些图像还允许抑制或去除局部异常值变化。 可以有意地引入材料性质的各向异性，例如磁导率或电导率，以用于评估由诸如冷加工或热处理的操作引起的材料状况。 各向异性由提供定向性质测量的传感器确定。 传感器方向性来自使用线性传导驱动段将磁场施加在测试材料中的结构。 维持该驱动段和相关感测元件相对于材料边缘的方向为边缘处的裂纹检测提供了增强的灵敏度。

公开(公告)号：US20070077436A1

公开(公告)日：2007-04-05

申请号：US11634285

申请日：2006-12-04

申请人： Basil Naji ,  John Cottier ,  Robert Lyons

发明人： Basil Naji ,  John Cottier ,  Robert Lyons

IPC分类号： B32B9/04

CPC分类号： B28B1/522 ,  B28B7/46 ,  C04B18/08 ,  C04B28/02 ,  C04B2111/00482 ,  C04B2111/00612 ,  E04C2/06 ,  E04F13/02 ,  E04F15/12 ,  Y02W30/92 ,  Y10S106/01 ,  Y10T428/249932 ,  Y10T428/249968 ,  Y10T428/249972 ,  Y10T428/249986 ,  Y10T428/25 ,  Y10T428/265 ,  Y10T428/31504 ,  Y10T428/31667 ,  Y10T442/10 ,  C04B20/008

摘要： The Abstract of the Disclosure filed herewith has replaced the previous Abstract of the Disclosure that begins with the words, “A composite product comprising a substrate layer” with the following paragraph: An exemplary composite product and method of manufacturing is provided. In one embodiment, the method includes dewatering a first slurry through a dewatering belt to form a first substrate layer, applying a first functional layer onto at least a portion of the first substrate layer, and dewatering a second slurry through the dewatering belt to form a second substrate layer. A first side of the second substrate layer may be overlayed onto the first functional layer, and the layers may be cured, and the layers bonded.

摘要翻译： 本文提交的披露摘要已经取代了以下开始于“包含基底层的复合产品”的以前的摘要摘要：提供了一种示例性的复合产品和制造方法。 在一个实施方案中，所述方法包括通过脱水带将第一浆料脱水以形成第一基材层，将第一功能层施加到第一基材层的至少一部分上，以及通过脱水带将第二浆料脱水形成 第二基板层。 第二衬底层的第一侧可以覆盖在第一功能层上，并且可以使层固化，并且层粘合。

公开(公告)号：US20060141049A1

公开(公告)日：2006-06-29

申请号：US11354415

申请日：2006-02-14

申请人： Robert Lyons ,  James Chang ,  John Trogden ,  Scott Whitcup

发明人： Robert Lyons ,  James Chang ,  John Trogden ,  Scott Whitcup

IPC分类号： A61K31/728 ,  A61K31/695 ,  A61K9/14

CPC分类号： A61K9/0048 ,  A61K31/56 ,  A61K31/573 ,  A61K47/36

摘要： Triamcinolone compositions, and methods of using such compositions, useful for injection into the vitreous of human eyes are provided. Such compositions can include triamcinolone particles present in a therapeutically effective amount, a viscosity inducing component, and an aqueous carrier component. The compositions have viscosities of at least about 10 cps or about 100 cps at a shear rate of 0.1/second. In a preferred embodiment, the viscosity is in the range of from about 80,000 cps to about 300,000 cps. The compositions advantageously suspend the triamcinolone particles for prolonged periods of time.

摘要翻译： 提供曲安奈德组合物，以及使用这些组合物的方法，其用于注射到人眼的玻璃体中。 这样的组合物可以包括以治疗有效量存在的曲安奈德颗粒，粘度诱导组分和水性载体组分。 组合物在0.1 /秒的剪切速率下具有至少约10cps或约100cps的粘度。 在优选的实施方案中，粘度在约80,000cps至约300,000cps的范围内。 组合物有利地将曲安奈德颗粒悬浮较长时间。

公开(公告)号：US20050250737A1

公开(公告)日：2005-11-10

申请号：US11091977

申请日：2005-03-28

申请人： Patrick Hughes ,  Laurent Delahaye ,  Michele Boix ,  James Chang ,  Robert Lyons

发明人： Patrick Hughes ,  Laurent Delahaye ,  Michele Boix ,  James Chang ,  Robert Lyons

IPC分类号： A61K9/00 ,  A61K31/573 ,  A61K31/724 ,  A61K47/36

CPC分类号： A61K9/0048 ,  A61K31/573 ,  A61K47/36 ,  A61K47/40

摘要： Pharmaceutical compositions suitable for administration into the interior of an eye of a person or animal are described. The present compositions include one or more components which are effective in providing a reduced toxicity relative to existing intraocular ophthalmic compositions. The present compositions include one or more therapeutic agents in amounts effective in providing a desired therapeutic effect when placed in an eye, and one or more retinal friendly excipients that have a reduced toxicity relative to benzyl alcohol or polysorbate 80. In certain compositions, the excipient component of the compositions comprises one or more cyclodextrins or cyclodextrin derivatives. Methods of using the compositions to treat ocular conditions are also described.

摘要翻译： 描述适于施用于人或动物的眼睛内部的药物组合物。 本发明组合物包括一种或多种有效提供相对于现有眼内眼用组合物的毒性降低的成分。 本发明的组合物包含一种或多种治疗剂，其用量在置于眼中时可提供所需的治疗效果，以及一种或多种视黄醛友好的赋形剂，其相对于苯甲醇或聚山梨酸酯80具有降低的毒性。在某些组合物中，赋形剂 组合物的组分包含一种或多种环糊精或环糊精衍生物。 还描述了使用组合物治疗眼睛病症的方法。