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公开(公告)号：US11206979B2
公开(公告)日：2021-12-28
申请号：US16256966
申请日：2019-01-24
Applicant: NeuroPace, Inc.
Inventor： Stephen T. Archer , Patrick Gerard Mulligan , David A. Greene
Abstract: An external data retrieval apparatus receives a low resolution version of a physiological signal from an active implantable medical device and determines if the physiological signal represents a clinically significant event. The apparatus provides an indication of such determination to the implantable medical device. If the physiological signal does represent a clinically significant event, the apparatus receives a full download of the physiological signal from the implantable device.
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公开(公告)号：US11547850B2
公开(公告)日：2023-01-10
申请号：US16692964
申请日：2019-11-22
Applicant: NeuroPace, Inc.
Inventor： Alfonso Chavez , David A. Greene
IPC: A61N1/05
Abstract: A lead fixation device for securing a first portion of a lead relative to a hole formed through a skull includes a skull attachment member having an upper surface and a lower surface and a bore extending through and between the upper surface and the lower surface. The lead fixation device also includes a lead compression mechanism integral with the skull attachment member and aligned with the bore of the skull attachment member. The lead compression mechanism defines a passageway through the lead fixation device, which passageway is characterized by a diameter that is defined by the lead compression mechanism. The lead compression mechanism is configured to transition the diameter from a first size to a second size greater than the first size upon insertion of an implant tool through the passageway, and from the second size to the first size upon removal of the implant tool from the passageway.
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公开(公告)号：US20220314002A1
公开(公告)日：2022-10-06
申请号：US17709227
申请日：2022-03-30
Applicant: NeuroPace, Inc.
Inventor： Sharanya Arcot Desai , David A. Greene
Abstract: An implanted neurostimulation system is configured to sense episodes of electrographic events and determine durations of episodes. Durations of electrographic events sensed by the implanted neurostimulation system are mapped with seizure probability biomarkers derived from records of the electrographic events to create a mapping function. A seizure probability biomarker that has a value desired for the operation of the implanted neurostimulation system is selected. The duration mapped to the selected seizure probability biomarker is identified and programmed into a control module of the implanted neurostimulation system as a programmed parameter that triggers the operation by the implanted neurostimulation system. The process may be repeated for other operations of the implanted neurostimulation system.
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公开(公告)号：US10231621B2
公开(公告)日：2019-03-19
申请号：US14270212
申请日：2014-05-05
Applicant: NeuroPace, Inc.
Inventor： Stephen T. Archer , Patrick Gerard Mulligan , David A. Greene
IPC: A61B5/00 , A61B5/04 , G06F19/00 , A61B5/0476
Abstract: An external data retrieval apparatus receives a low resolution version of a physiological signal from an active implantable medical device and determines if the physiological signal represents a clinically significant event. The apparatus provides an indication of such determination to the implantable medical device. If the physiological signal does represent a clinically significant event, the apparatus receives a full download of the physiological signal from the implantable device.
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公开(公告)号：US09782595B2
公开(公告)日：2017-10-10
申请号：US14955978
申请日：2015-12-01
Applicant: NeuroPace, Inc.
Inventor： David A. Greene , Steve T. Archer , Patrick G. Mulligan, IV
CPC classification number: A61N1/37252 , A61N1/37276
Abstract: An external data retrieval apparatus includes a transceiver, and a processing system coupled to the transceiver. The processing system obtains a plurality of measures over a period of time. The measures relate to a quality of a communications channel between the data retrieval apparatus and an active implantable medical device. The processing system determines a trend in the plurality of measures over the period of time, and then determines a preferred time during which to retrieve data based on the trend.
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Patent Agency Ranking
公开(公告)号：US11813035B2
公开(公告)日：2023-11-14
申请号：US17521652
申请日：2021-11-08
Applicant: NeuroPace, Inc.
Inventor： Stephen T. Archer , Patrick Gerard Mulligan , David A. Greene
CPC classification number: A61B5/00 , A61B5/0002 , A61B5/0031 , A61B5/24 , A61B5/316 , A61B5/4094 , A61B5/7282 , G16H10/60 , G16H10/65 , G16H40/63 , A61B5/369 , A61B2560/0209
Abstract: An external data retrieval apparatus receives a low resolution version of a physiological signal from an active implantable medical device and determines if the physiological signal represents a clinically significant event. The apparatus provides an indication of such determination to the implantable medical device. If the physiological signal does represent a clinically significant event, the apparatus receives a full download of the physiological signal from the implantable device.
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公开(公告)号：US20200171299A1
公开(公告)日：2020-06-04
申请号：US16692964
申请日：2019-11-22
Applicant: NeuroPace, Inc.
Inventor： Alfonso Chavez , David A. Greene
IPC: A61N1/05
Abstract: A lead fixation device for securing a first portion of a lead relative to a hole formed through a skull includes a skull attachment member having an upper surface and a lower surface and a bore extending through and between the upper surface and the lower surface. The lead fixation device also includes a lead compression mechanism integral with the skull attachment member and aligned with the bore of the skull attachment member. The lead compression mechanism defines a passageway through the lead fixation device, which passageway is characterized by a diameter that is defined by the lead compression mechanism. The lead compression mechanism is configured to transition the diameter from a first size to a second size greater than the first size upon insertion of an implant tool through the passageway, and from the second size to the first size upon removal of the implant tool from the passageway.
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公开(公告)号：US09480847B2
公开(公告)日：2016-11-01
申请号：US14955960
申请日：2015-12-01
Applicant: NeuroPace, Inc.
Inventor： David A. Greene , Steve T. Archer , Patrick G. Mulligan, IV
CPC classification number: A61N1/37252 , A61N1/37276
Abstract: An external data retrieval apparatus includes a transceiver, and a processing system coupled to the transceiver. The processing system obtains a plurality of measures over a period of time. The measures relate to a quality of a communications channel between the data retrieval apparatus and an active implantable medical device. The processing system determines a trend in the plurality of measures over the period of time, and then determines a preferred time during which to retrieve data based on the trend.
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公开(公告)号：US20230172529A1
公开(公告)日：2023-06-08
申请号：US18070902
申请日：2022-11-29
Applicant: NeuroPace, Inc.
Inventor： Sharanya Arcot Desai , Thomas K. Tcheng , Cairn G. Seale , Martha J. Morrell , David A. Greene
CPC classification number: A61B5/4094 , A61B5/7264 , G16H20/40 , A61B5/6868
Abstract: A method of assessing electrical activity of a brain includes, for each of a plurality of electrical-activity records of the brain, applying a machine-learned ESC model to the record to classify the record as one of a seizure record or a non-seizure record, wherein each of record is sensed by a corresponding one of a plurality of sensing channels of an implanted medical device; for each seizure record in a set of seizure records, applying the machine-learned ESC model to the seizure record to classify the seizure record as one of a local-seizure record or a spread-seizure record, wherein the seizure record comprises a first seizure record captured by a first sensing channel and a second seizure record captured by a second sensing channel; and for each spread-seizure record in a set of spread-seizure records, applying a machine-learned SSC model to the spread-seizure record to classify the spread-seizure record as a type of seizure spread pattern.
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公开(公告)号：US10543360B2
公开(公告)日：2020-01-28
申请号：US15721539
申请日：2017-09-29
Applicant: NeuroPace, Inc.
Inventor： Emily A. Mirro , Jacob A. Mandell , David A. Greene
Abstract: A lead fixation accessory configured to be positioned over a skull hole and to transition between an opened state and a closed state during a lead implant procedure protects against lead migration by providing a mechanism for securing the lead in place at the skull hole while a stylet is removed from the lead. The lead fixation accessory remains in place after the implant procedure to provide chronic lead stability. A lead stabilization tool configured to access and grip a lead through a slotted cannula during the lead implant procedure also protects against lead migration by providing a mechanism for securing the lead in place at a point where the lead exits the skull hole while the slotted cannula is removed from the skull hole and peeled away from the lead.
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