专利检索 ap:("Nico Ghilardi" OR "Frederic De Sauvage" OR "Audrey Goddard" OR "Paul Godowski" OR "J. Grimaldi" OR "Austin Gurney" OR "William Wood") AND inv:"Austin Gurney" 第 1 页

1.

发明申请
NOVEL TYPE-1 CYTOKINE RECEPTOR GLM-R 审中-公开
标题翻译：新型1型细胞因子受体GLM-R

公开(公告)号：US20070136829A1

公开(公告)日：2007-06-14

申请号：US11548639

申请日：2006-10-11

申请人： Nico Ghilardi , Frederic De Sauvage , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , William Wood

发明人： Nico Ghilardi , Frederic De Sauvage , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , William Wood

IPC分类号： A01K67/027 , C12Q1/68 , G01N33/53 , G01N33/567 , C07H21/04 , C12P21/06 , C07K14/705

CPC分类号： C07K14/7158

摘要： The present invention is directed to novel polypeptides and variants thereof of GLM-R polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided are methods for detecting agents that modulate the activity of GLM-R. Also provided are methods for diagnosing and for treating disorders characterized by the over or under abundance of monocytes or macrophages.

摘要翻译： 本发明涉及GLM-R多肽的新型多肽及其变体以及编码这些多肽的核酸分子。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。还提供了用于检测调节GLM-R的活性的试剂的方法。还提供了用于诊断和治疗特征在于单核细胞或巨噬细胞过度或不丰富的疾病的方法。

2.

发明申请
NUCLEIC ACID ENCODING NOVEL TYPE-1 CYTOKINE RECEPTOR GLM-R 失效
标题翻译：核酸编码新型1型细胞因子受体GLM-R

公开(公告)号：US20070174922A1

公开(公告)日：2007-07-26

申请号：US10373512

申请日：2003-02-24

申请人： Nico Ghilardi , Frederic de Sauvage , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , William Wood

发明人： Nico Ghilardi , Frederic de Sauvage , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , William Wood

IPC分类号： A01K67/027 , C12Q1/68 , G01N33/567 , C07H21/04 , C12P21/06 , C12N5/06 , C07K14/705 , C07K16/28

CPC分类号： C07K14/7158

摘要： The present invention is directed to novel polypeptides having sequence similarity to Interleukin 6 receptor and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及与白细胞介素6受体具有序列相似性的新型多肽和编码这些多肽的核酸分子。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。

3.

发明申请
Nucleic acid underexpressed in stomach tumor and lung tumor 审中-公开
标题翻译：核酸在胃肿瘤和肺肿瘤中不显着

公开(公告)号：US20060160186A1

公开(公告)日：2006-07-20

申请号：US11376673

申请日：2006-03-14

申请人： Dan Eaton , Ellen Filvaroff , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Colin Watanabe , William Wood

发明人： Dan Eaton , Ellen Filvaroff , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Colin Watanabe , William Wood

IPC分类号： C07H21/04 , C12P21/06 , C12N1/21 , C07K14/705 , C07K14/525

CPC分类号： C07K14/47 , C07K14/4748

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。

4.

发明申请
Secreted and transmembrane polypeptides and nucleic acids encoding the same 审中-公开

公开(公告)号：US20060105427A1

公开(公告)日：2006-05-18

申请号：US11296092

申请日：2005-12-06

申请人： Kevin Baker , David Botstein , Dan Eaton , Napoleone Ferrara , Ellen Filvaroff , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Kenneth Hillan , Ivar Kljavin , Mary Napier , Margaret Roy , Daniel Tumas , William Wood

发明人： Kevin Baker , David Botstein , Dan Eaton , Napoleone Ferrara , Ellen Filvaroff , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Kenneth Hillan , Ivar Kljavin , Mary Napier , Margaret Roy , Daniel Tumas , William Wood

IPC分类号： C12P21/06 , C07H21/04 , C12N9/00 , C12N5/06 , C12N1/18 , C07K14/47 , C07K16/18

CPC分类号： C07K14/47

摘要： The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

5.

发明申请
Secreted and transmembrane polypeptides and nucleic acids encoding the same 有权

公开(公告)号：US20060051779A1

公开(公告)日：2006-03-09

申请号：US11103195

申请日：2005-04-11

申请人： Dan Eaton , Ellen Filvaroff , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Colin Watanabe , William Wood

发明人： Dan Eaton , Ellen Filvaroff , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Colin Watanabe , William Wood

IPC分类号： C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/82

CPC分类号： C07K14/47 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

6.

发明申请
SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME 有权

公开(公告)号：US20060008901A1

公开(公告)日：2006-01-12

申请号：US10063703

申请日：2002-05-08

申请人： Dan Eaton , Ellen Filvaroff , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Colin Watanabe , William Wood

发明人： Dan Eaton , Ellen Filvaroff , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Colin Watanabe , William Wood

IPC分类号： C12N9/00 , C07H21/04 , C12P21/06 , C12N5/06 , C07K14/47

CPC分类号： C07K14/47 , A61K38/00 , C07K14/4748 , C07K14/705 , C07K14/82 , C07K16/18 , C07K16/30 , C07K16/3023 , C07K16/3046 , C07K16/3053 , C07K16/40 , C07K2319/30 , C12N5/06 , Y10S530/866

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

7.

发明申请
Antibodies to polypeptides encoded by a nucleic acid underexpressed in esophageal tumor 有权
标题翻译：由在食管肿瘤中未表达的核酸编码的多肽的抗体

公开(公告)号：US20050260647A1

公开(公告)日：2005-11-24

申请号：US11102240

申请日：2005-04-08

申请人： Dan Eaton , Ellen Filvaroff , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Colin Watanabe , William Wood

发明人： Dan Eaton , Ellen Filvaroff , Mary Gerritsen , Audrey Goddard , Paul Godowski , J. Grimaldi , Austin Gurney , Colin Watanabe , William Wood

IPC分类号： C12Q1/68 , G01N33/574

CPC分类号： G01N33/57484

摘要： The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.

摘要翻译： 本发明涉及新型多肽和编码那些多肽的核酸分子。本文还提供了包含那些核酸序列的载体和宿主细胞，包含与异源多肽序列融合的本发明的多肽的嵌合多肽分子，与本发明的多肽结合的抗体以及本发明的多肽的制备方法发明。