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    Electrochemical sensor
    1.
    发明授权
    Electrochemical sensor 失效
    电化学传感器

    公开(公告)号：US5628890A

    公开(公告)日：1997-05-13

    申请号：US534876

    申请日：1995-09-27

    申请人： Nigel F. Carter ,  Geoffrey R. Chambers ,  Graham J. Hughes ,  Steven Scott ,  Gurdial S. Sanghera ,  Jared L. Watkin

    发明人： Nigel F. Carter ,  Geoffrey R. Chambers ,  Graham J. Hughes ,  Steven Scott ,  Gurdial S. Sanghera ,  Jared L. Watkin

    IPC分类号： G01N27/327 ,  C12Q1/00 ,  G01N27/26

    CPC分类号： C12Q1/001 ,  Y10S435/817

    摘要： An electrode strip for use in an electrochemical sensor for measuring a compound in a sample is provided, including an electrode support, a reference or counter electrode disposed on the support, a working electrode spaced from the reference or counter electrode on the support, a covering layer defining an enclosed space over the reference and working electrodes and having an aperture for receiving a sample into the enclosed space, and a plurality of mesh layers interposed in the enclosed space between the covering layer and the support, the covering layer having a sample application aperture spaced from said electrodes and said reference electrode spaced from said working electrode at a position remote from and on the opposite side of said working electrode from said aperture. The working electrode includes an enzyme capable of catalyzing a reaction involving a substrate for the enzyme or a substrate catalytically reactive with an enzyme and a mediator capable of transferring electrons transferred between the enzyme-catalyzed reaction and the working electrode to create a current representative of the activity of the enzyme and representative of the compound.

    摘要翻译： 提供了用于测量样品中化合物的电化学传感器的电极条，包括设置在支撑体上的电极支撑体，参考电极或对电极，与支撑体上的参考电极或对电极隔开的工作电极， 层限定在参考电极和工作电极上的封闭空间，并具有用于将样品接收到封闭空间中的孔，以及插入在覆盖层和支撑体之间的封闭空间中的多个网格层，覆盖层具有样品应用 与所述电极间隔开的孔，并且所述参考电极在远离所述工作电极的离开所述孔的位置处和与所述工作电极间隔开的位置处。 工作电极包括能够催化涉及用于酶的底物或与酶催化反应的底物的反应的酶和能够转移在酶催化反应和工作电极之间转移的电子的介体，以产生代表 酶的活性和化合物的代表。