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1.发明授权Device for detecting and eliminating accumulator fluid leakage through control valve 失效用于通过控制阀检测和消除累加器流体泄漏的装置
公开(公告)号：US5221125A
公开(公告)日：1993-06-22
申请号：US711651
申请日：1991-06-06
CPC分类号： B60T13/12 , B60T17/221 , B60T8/3615 , B60T8/445 , B60T8/4836 , B60T8/94 , Y10S303/04
摘要： A fluid leakage preventing device incorporated in a hydraulically-operated system which includes an accumulator for storing a working fluid under pressure, an actuator operated by the fluid supplied from the accumulator, and a control valve having an open position and a closed position for fluid communication and disconnection between the accumulator and the actuator, respectively. The fluid leakage preventing device includes a fluid leakage detector for generating an output signal indicative of the leakage flow of the fluid from said accumulator through the control valve placed in the closed position. The device further includes a valve reciprocating arrangement responsive to the output signal of said fluid leakage detector, for effecting at least one reciprocating movement of a valving member of the control valve.
摘要翻译： 一种结合在液压操作系统中的流体泄漏防止装置，其包括用于存储压力下的工作流体的蓄能器，由蓄能器供应的流体操作的致动器以及具有用于流体连通的打开位置和关闭位置的控制阀 以及蓄能器和致动器之间的断开。 流体泄漏防止装置包括：流体泄漏检测器，用于产生表示来自所述蓄能器的流体通过置于关闭位置的控制阀的泄漏流的输出信号。 该装置还包括响应于所述流体泄漏检测器的输出信号的阀往复装置，用于实现控制阀的阀构件的至少一个往复运动。
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公开(公告)号：US08835173B2
公开(公告)日：2014-09-16
申请号：US11754568
申请日：2007-05-29
IPC分类号： C12N5/00
CPC分类号： C12N5/0068 , C12M25/02 , C12N2533/30 , C12N2535/10
摘要： An object of the present invention is to provide a means capable of transferring a cell sheet, a cell pattern or the like to a desired material at a high speed. The present invention provides a substrate for cell culture comprising a base and a cell adhesive region formed on a surface of the base, wherein the cell adhesive region is formed of a film that is rendered cell adhesive by applying an oxidation treatment and/or a decomposition treatment to a cell-adhesion inhibitory hydrophilic film containing an organic compound having a carbon-oxygen bond.
摘要翻译： 本发明的目的是提供能够高速地将细胞片，细胞图案等转移到期望的材料的装置。 本发明提供一种细胞培养用基材，其特征在于，在基材的表面形成有基材和细胞粘合剂区域，其中，所述细胞粘合剂区域由通过进行氧化处理和/或分解而成为细胞粘合剂的膜形成 对含有具有碳 - 氧键的有机化合物的细胞粘附抑制性亲水膜的处理。
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公开(公告)号：US06681620B2
公开(公告)日：2004-01-27
申请号：US10096134
申请日：2002-03-11
IPC分类号： G01L528
CPC分类号： G01N19/02 , G01N2203/0025 , G01N2203/0676
摘要： A method and apparatus for conducting a vehicle performance evaluation test by automatically depressing a control member of the vehicle to be depressed by a vehicle operator uses an actuator of a vehicle performance evaluation test apparatus. The actuator depresses the control member, the actuator having a first end and a second end. The first end of the actuator is fixed to a seat of the vehicle. The second end of the actuator is engaged with the control member of the vehicle. The actuator is caused to exert a depressing force to depress the control member relative to the seat so as to automatically depress the control member.
摘要翻译： 通过自动按下由车辆操作者按压的车辆的控制部件进行车辆性能评价试验的方法和装置使用车辆性能评价试验机的致动器。 致动器按压控制构件，致动器具有第一端和第二端。 致动器的第一端固定在车辆的座椅上。 致动器的第二端与车辆的控制构件接合。 使致动器施加按压力以相对于座椅按压控制构件，以便自动地按压控制构件。
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公开(公告)号：US08592139B2
公开(公告)日：2013-11-26
申请号：US11936836
申请日：2007-11-08
CPC分类号： G01N33/5005
摘要： The present invention provides a method for performing a biological test under conditions in which an artificially prepared cell pattern with initial position coordinates that can be determined is three-dimensionally cultured within a gelled matrix. The present invention relates to a biological test method that comprises testing a biological indicator with reference to at least one selected from the group consisting of cell proliferation, cell movement, and cell differentiation in a cell pattern substantially embedded in gel. The present invention also relates to a kit for the biological test method.
摘要翻译： 本发明提供一种用于在可以测定初始位置坐标的人造制备的细胞图案在凝胶化基质内三维培养的条件下进行生物测试的方法。 本发明涉及一种生物测试方法，其包括参考选自基本上嵌入凝胶中的细胞图案中的细胞增殖，细胞运动和细胞分化中的至少一种来测试生物学指示剂。 本发明还涉及用于生物测试方法的试剂盒。
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公开(公告)号：US08293933B2
公开(公告)日：2012-10-23
申请号：US12327835
申请日：2008-12-04
申请人： Norihiko Okochi
发明人： Norihiko Okochi
CPC分类号： C07F7/1804 , C07B2200/11
摘要： The object of the present invention is to inexpensively produce a carrier having a hydrophilic spacer, for immobilizing biological materials, etc., which has been very expensive so far. The present invention relates to a method of producing a substance immobilizing carrier, in which carboxyl groups or active ester groups are positioned on a support, which is characterized by including: a functional group-introducing step in which a functional group is introduced on a surface of a support; a hydrophilic compound binding step in which a hydrophilic compound having a binding group that can bind with the functional group and a hydroxyl group, is bound to the functional group through binding between the functional group and the binding group; a carboxyl group-forming step in which a carboxyl group is formed through ring-opening half-esterification between a cyclic acid anhydride and a hydroxyl group on the bound hydrophilic compound; and, if necessary, an active esterification step in which the carboxyl group formed in the carboxyl group forming step is converted into an active ester.
摘要翻译： 本发明的目的是廉价地制造具有亲水间隔物的载体，用于固定生物材料等，迄今为止非常昂贵。 本发明涉及一种固定载体的方法，其中羧基或活性酯基位于载体上，其特征在于包括：官能团引入步骤，其中官能团引入到表面上 的支持; 亲水性化合物结合步骤，其中具有可与官能团结合的结合基团和羟基的亲水性化合物通过官能团和结合基团之间的结合与官能团结合; 羧基形成步骤，其中通过在结合的亲水性化合物上的环状酸酐和羟基之间的开环半酯化形成羧基; 如果需要，将羧基形成步骤中形成的羧基转化为活性酯的活性酯化步骤。
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公开(公告)号：US20070274968A1
公开(公告)日：2007-11-29
申请号：US11754568
申请日：2007-05-29
CPC分类号： C12N5/0068 , C12M25/02 , C12N2533/30 , C12N2535/10
摘要： An object of the present invention is to provide a means capable of transferring a cell sheet, a cell pattern or the like to a desired material at a high speed. The present invention provides a substrate for cell culture comprising a base and a cell adhesive region formed on a surface of the base, wherein the cell adhesive region is formed of a film that is rendered cell adhesive by applying an oxidation treatment and/or a decomposition treatment to a cell-adhesion inhibitory hydrophilic film containing an organic compound having a carbon-oxygen bond.
摘要翻译： 本发明的目的是提供能够高速地将细胞片，细胞图案等转移到期望的材料的装置。 本发明提供一种细胞培养用基材，其特征在于，在基材的表面形成有基材和细胞粘合剂区域，其中，所述细胞粘合剂区域由通过进行氧化处理和/或分解而成为细胞粘合剂的膜形成 对含有具有碳 - 氧键的有机化合物的细胞粘附抑制性亲水膜的处理。
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7.发明授权Test kit comprising a culture instrument with a cell pattern and a gel suitable to embed cell pattern 有权测试试剂盒包括具有细胞图案和适于嵌入细胞图案的凝胶的培养仪器公开(公告)号：US08741645B2
公开(公告)日：2014-06-03
申请号：US13092552
申请日：2011-04-22
CPC分类号： G01N33/5008 , G01N33/5029 , G01N33/5032
摘要： The present invention provides a method for performing a biological test under conditions in which an artificially prepared cell pattern with initial position coordinates that can be determined is three-dimensionally cultured within a gelled matrix. The present invention relates to a biological test method that comprises testing a biological indicator with reference to at least one selected from the group consisting of cell proliferation, cell movement, and cell differentiation in a cell pattern substantially embedded in gel. The present invention also relates to a kit for the biological test method.
摘要翻译： 本发明提供一种用于在可以测定初始位置坐标的人造制备的细胞图案在凝胶化基质内三维培养的条件下进行生物测试的方法。 本发明涉及一种生物测试方法，其包括参考选自基本上嵌入凝胶中的细胞图案中的细胞增殖，细胞运动和细胞分化中的至少一种来测试生物学指示剂。 本发明还涉及用于生物测试方法的试剂盒。
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公开(公告)号：US20080113334A1
公开(公告)日：2008-05-15
申请号：US11936836
申请日：2007-11-08
IPC分类号： C12Q1/00
CPC分类号： G01N33/5005
摘要： The present invention provides a method for performing a biological test under conditions in which an artificially prepared cell pattern with initial position coordinates that can be determined is three-dimensionally cultured within a gelled matrix. The present invention relates to a biological test method that comprises testing a biological indicator with reference to at least one selected from the group consisting of cell proliferation, cell movement, and cell differentiation in a cell pattern substantially embedded in gel. The present invention also relates to a kit for the biological test method.
摘要翻译： 本发明提供一种用于在可以测定初始位置坐标的人造制备的细胞图案在凝胶化基质内三维培养的条件下进行生物测试的方法。 本发明涉及一种生物测试方法，其包括参考选自基本上嵌入凝胶中的细胞图案中的细胞增殖，细胞运动和细胞分化中的至少一种来测试生物指示剂。 本发明还涉及用于生物测试方法的试剂盒。
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