公开(公告)号：US20240002843A1

公开(公告)日：2024-01-04

申请号：US17965366

申请日：2022-10-13

Applicant: Novartis AG ,  Intellia Therapeutics, Inc.

Inventor： Anthony Edward BOITANO ,  Michael COOKE ,  Lloyd B. KLICKSTEIN ,  Reynald LESCARBEAU ,  Craig Stephen MICKANIN ,  Kabungo MULUMBA ,  Seshidhar Reddy POLICE ,  Jennifer SNEAD ,  Susan C. STEVENSON ,  Morag STEWART ,  Yi YANG

IPC: C12N15/113 ,  A61K35/15 ,  A61P7/00

CPC classification number: C12N15/113 ,  A61K35/15 ,  A61P7/00 ,  C12N2310/315 ,  C12N2310/322 ,  C12N2310/10 ,  C12N2310/321 ,  C12N2310/20

Abstract: The present invention is directed to genome editing systems, reagents and methods for the treatment of hemoglobinopathies.

公开(公告)号：US20250127809A1

公开(公告)日：2025-04-24

申请号：US18569029

申请日：2022-06-22

Applicant: Novartis AG

Inventor： Muluken Shambel BELEW ,  Jennifer Stroka COBB ,  Carsten RUSS ,  Frederic SIGOILLOT ,  Susan C. STEVENSON ,  Pamela YF TING

IPC: A61K35/14 ,  A61K35/12 ,  A61P7/00 ,  C12N5/071 ,  C12N9/22 ,  C12N15/113 ,  C12N15/52

Abstract: The present invention is directed to compositions and methods for the treatment of hemoglobinopathies.

公开(公告)号：US20230279394A1

公开(公告)日：2023-09-07

申请号：US17786347

申请日：2020-12-16

Applicant: Novartis AG

Inventor： Muluken BELEW ,  Simone BONAZZI ,  James BRADNER ,  Artiom CERNIJENKO ,  Jennifer Stroka COBB ,  Natalie DALES ,  John Ryan KERRIGAN ,  Philip LAM ,  Hasnain Ahmed MALIK ,  Carsten RUSS ,  Frederic SIGOILLOT ,  Susan C. STEVENSON ,  Noel Marie-France THOMSEN ,  Pamela TING

IPC: C12N15/113 ,  C12N15/86 ,  C12N5/07 ,  A61P7/00

CPC classification number: C12N15/113 ,  A61P7/00 ,  C12N5/06 ,  C12N15/86 ,  C12N2310/20

Abstract: The present invention is directed to compositions and methods for the treatment of hemoglobinopathies.

公开(公告)号：US20190010495A1

公开(公告)日：2019-01-10

申请号：US16066617

申请日：2016-12-26

Applicant: NOVARTIS AG ,  INTELLIA THERAPEUTICS, INC.

Inventor： Anthony Edward BOITANO ,  Michael COOKE ,  Lloyd B. KLICKSTEIN ,  Reynald LESCARBEAU ,  Craig Stephen MICKANIN ,  Kabungo MULUMBA ,  Seshidhar Reddy POLICE ,  Jennifer SNEAD ,  Susan C. STEVENSON ,  Morag STEWART ,  Yi YANG

IPC: C12N15/113 ,  A61P7/00 ,  A61K35/15

Abstract: The present invention is directed to genome editing systems, reagents and methods for the treatment of hemoglobinopathies.