公开(公告)号：US20160304905A1

公开(公告)日：2016-10-20

申请号：US15101252

申请日：2014-12-03

Applicant: NOVOZYMES A/S

Inventor： Bjarne G. Hansen ,  Carsten Lillelund Olsen ,  Jesper Vind

IPC: C12N15/90 ,  C12N15/80

CPC classification number: C12N15/902 ,  C12N15/80

Abstract: The present invention relates to a method for site-specific chromosomal integration of a gene library in a filamentous fungal host cell and a polynucleotide construct suitable for this purpose.

Abstract translation: 本发明涉及丝状真菌宿主细胞中基因文库的位点特异性染色体整合方法和适用于该目的的多核苷酸构建体。

公开(公告)号：US09695406B2

公开(公告)日：2017-07-04

申请号：US14773673

申请日：2014-03-06

Applicant: NOVOZYMES A/S

Inventor： Esben P. Friis ,  Jesper Vind ,  Leonardo De Maria ,  Bjarne G. Hansen

IPC: C12N9/18 ,  C12N9/34 ,  C12P7/14

CPC classification number: C12N9/2428 ,  C12P7/14 ,  C12Y302/01003

Abstract: The present invention relates to glucoamylase variants having increased thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20160046916A1

公开(公告)日：2016-02-18

申请号：US14773673

申请日：2014-03-06

Applicant: NOVOZYMES A/S

Inventor： Esben P. Friis ,  Jesper Vind ,  Leonardo De Maria ,  Bjarne G. Hansen

IPC: C12N9/34 ,  C12P7/14

CPC classification number: C12N9/2428 ,  C12P7/14 ,  C12Y302/01003

Abstract: The present invention relates to glucoamylase variants having increased thermostability. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract translation: 本发明涉及具有增加的热稳定性的葡糖淀粉酶变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。

公开(公告)号：US09771566B2

公开(公告)日：2017-09-26

申请号：US15036530

申请日：2014-11-28

Applicant: Novozymes A/S

Inventor： Bjarne G. Hansen ,  Lars Kobberoe Skov ,  Leonardo De Maria ,  Julie Bille Rannes

IPC: C12N9/16 ,  A62D3/02 ,  C12N9/18 ,  A62D101/02 ,  A62D101/04 ,  A62D101/26

CPC classification number: C12N9/16 ,  A62D3/02 ,  A62D2101/02 ,  A62D2101/04 ,  A62D2101/26 ,  C12N9/18 ,  C12Y301/08001

Abstract: The present invention relates to organophosphorous hydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

公开(公告)号：US20160289654A1

公开(公告)日：2016-10-06

申请号：US15036530

申请日：2014-11-28

Applicant: Novozymes A/S

Inventor： Bjarne G. Hansen ,  Lars Kobberoe Skov ,  Leonardo De Maria ,  Julie Bille Rannes

IPC: C12N9/16 ,  A62D3/02

CPC classification number: C12N9/16 ,  A62D3/02 ,  A62D2101/02 ,  A62D2101/04 ,  A62D2101/26 ,  C12N9/18 ,  C12Y301/08001

Abstract: The present invention relates to organophosphorous hydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract translation: 本发明涉及有机磷水解酶变体。 本发明还涉及编码这些变体的多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞; 以及使用这些变体的方法。