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1.发明申请One-Phase Microemulsion Compositions, O/W Ultrafine Emulsion External Formulations And Method For Producing The Same 有权单相微乳液组合物，O / W超细乳液外用制剂及其制备方法公开(公告)号：US20080153929A1
公开(公告)日：2008-06-26
申请号：US10585262
申请日：2005-01-06
IPC分类号： B01F3/08
摘要： A one-phase microemulsion composition, which can be easily prepared without the use of special equipment, has high safety, and stays stable for a long period in an ultrafine emulsion state when the composition is added to an aqueous formulation, is provided by appropriately adjusting the ratio of (A) a hydrophilic nonionic surfactant, (B) a lipophilic nonionic surfactant, (C) an oil component, (D) a water-miscible solvent that does not interdissolve with the oil component, and the critical micelle concentration (CMC) of the hydrophilic nonionic surfactant in the water-miscible solvent is higher than that of the hydrophilic nonionic surfactant in water, and (E) water.
摘要翻译： 可以在不使用特殊设备的情况下容易地制备的单相微乳液组合物具有高安全性，并且当将组合物加入到水性制剂中时，在超细乳液状态下长时间保持稳定，通过适当调节 （A）亲水性非离子表面活性剂，（B）亲油性非离子表面活性剂，（C）油组分，（D）与油组分不溶解的水混溶性溶剂和临界胶束浓度（CMC ）在水溶性溶剂中的亲水性非离子表面活性剂高于水中的亲水性非离子表面活性剂，（E）水。
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2.发明授权One-phase microemulsion compositions, O/W ultrafine emulsion external formulations and method for producing the same 有权单相微乳液组合物，O / W超细乳液外用制剂及其制备方法公开(公告)号：US08461214B2
公开(公告)日：2013-06-11
申请号：US10585262
申请日：2005-01-06
摘要： A one-phase microemulsion composition, which can be easily prepared without the use of special equipment, has high safety, and stays stable for a long period in an ultrafine emulsion state when the composition is added to an aqueous formulation, is provided by appropriately adjusting the ratio of (A) a hydrophilic nonionic surfactant, (B) a lipophilic nonionic surfactant, (C) an oil component, (D) a water-miscible solvent that does not interdissolve with the oil component, and the critical micelle concentration (CMC) of the hydrophilic nonionic surfactant in the water-miscible solvent is higher than that of the hydrophilic nonionic surfactant in water, and (E) water.
摘要翻译： 可以在不使用特殊设备的情况下容易地制备的单相微乳液组合物具有高安全性，并且当将组合物加入到水性制剂中时，在超细乳液状态下长时间保持稳定，通过适当调节 （A）亲水性非离子表面活性剂，（B）亲油性非离子表面活性剂，（C）油组分，（D）与油组分不溶解的水混溶性溶剂和临界胶束浓度（CMC ）在水溶性溶剂中的亲水性非离子表面活性剂高于水中的亲水性非离子表面活性剂，（E）水。
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公开(公告)号：US08404258B2
公开(公告)日：2013-03-26
申请号：US12074394
申请日：2008-03-04
申请人： Nozomi Oguchi , Reiji Miyahara , Hiroyuki Kakoki , Takashi Ohmori
发明人： Nozomi Oguchi , Reiji Miyahara , Hiroyuki Kakoki , Takashi Ohmori
CPC分类号： A61Q19/00 , A61K8/39 , A61Q1/02 , A61Q1/06 , A61Q1/12 , A61Q1/14 , A61Q5/00 , A61Q5/02 , A61Q17/04 , A61Q19/10
摘要： A skin treatment composition that characteristically contains alkylene polyglycol dineopentanoate having a specific structure.The object is to provide a skin treatment composition that gives a refreshing sensation at the time of application and contains an oil component that is highly safe with low skin irritation.The skin treatment composition specifically contains diethyleneglycol dineopentanoate, triethyleneglycol dineopentanoate, tetraethyleneglycol dineopentanoate, dipropyleneglycol dineopentanoate, tripropyleneglycol dineopentanoate, etc.Dipropyleneglycol dineopentanoate and tripropyleneglycol dineopentanoate are particularly preferable in terms of the sensation at the time of application; they provide a skin treatment composition that is particularly superior in absorption into the skin and a sensation of permeation and highly safe.
摘要翻译： 特征在于含有具有特定结构的亚烷基二醇二新戊酸酯的皮肤处理组合物。 本发明的目的是提供一种皮肤处理组合物，其在使用时具有清爽感，并且含有高度安全且低皮肤刺激性的油性成分。 皮肤治疗组合物具体包含二甘醇二全新戊酸酯，三甘醇二全新戊酸酯，四甘醇二全新戊酸酯，二丙二醇二全新戊酸酯，三丙二醇二全新戊酸酯等。二丙二醇二全新戊酸酯和三丙二醇二全新戊酸酯在使用时的感觉方面是特别优选的; 它们提供了对皮肤吸收特别优异的渗透感和高度安全性的皮肤处理组合物。
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公开(公告)号：US20080293811A1
公开(公告)日：2008-11-27
申请号：US12074394
申请日：2008-03-04
申请人： Nozomi Oguchi , Reiji Miyahara , Hiroyuki Kakoki , Takashi Ohmori
发明人： Nozomi Oguchi , Reiji Miyahara , Hiroyuki Kakoki , Takashi Ohmori
IPC分类号： A61K31/225 , A61P17/00
CPC分类号： A61Q19/00 , A61K8/39 , A61Q1/02 , A61Q1/06 , A61Q1/12 , A61Q1/14 , A61Q5/00 , A61Q5/02 , A61Q17/04 , A61Q19/10
摘要： A skin treatment composition that characteristically contains alkylene polyglycol dineopentanoate having a specific structure.The object is to provide a skin treatment composition that gives a refreshing sensation at the time of application and contains an oil component that is highly safe with low skin irritation.The skin treatment composition specifically contains diethyleneglycol dineopentanoate, triethyleneglycol dineopentanoate, tetraethyleneglycol dineopentanoate, dipropyleneglycol dineopentanoate, tripropyleneglycol dineopentanoate, etc.Dipropyleneglycol dineopentanoate and tripropyleneglycol dineopentanoate are particularly preferable in terms of the sensation at the time of application; they provide a skin treatment composition that is particularly superior in absorption into the skin and a sensation of permeation and highly safe.
摘要翻译： 特征在于含有具有特定结构的亚烷基二醇二新戊酸酯的皮肤处理组合物。 本发明的目的是提供一种皮肤处理组合物，其在使用时具有清爽感，并且含有高度安全且低皮肤刺激性的油性成分。 皮肤治疗组合物具体包含二甘醇二全新戊酸酯，三甘醇二全新戊酸酯，四甘醇二全新戊酸酯，二丙二醇二全新戊酸酯，三丙二醇二全新戊酸酯等。二丙二醇二全新戊酸酯和三丙二醇二全新戊酸酯在使用时的感觉方面是特别优选的; 它们提供了对皮肤吸收特别优异的渗透感和高度安全性的皮肤处理组合物。
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公开(公告)号：US20050180931A1
公开(公告)日：2005-08-18
申请号：US10513823
申请日：2003-03-07
申请人： Nozomi Oguchi , Reiji Miyahara , Hiroyuki Kakoki , Takayuki Omura
发明人： Nozomi Oguchi , Reiji Miyahara , Hiroyuki Kakoki , Takayuki Omura
摘要： The present invention is a skin treatment composition that characteristically contains an alkyl benzoate represented by the following general formula (1). This provides a skin treatment composition that gives a refreshing sensation at the time of application and can contain drugs and ultraviolet absorbents in a stable manner. Also, the present invention is a sunblock water-in-oil type emulsified cosmetic characteristically comprising an ester bond product of polyhydroxystearic acid represented by the following general formulas (2) or (3), alkyl benzoate represented by the following general formula (1), and an ultraviolet absorbent. This provides a sunblock cosmetic consisting of a water-in-oil type emulsified composition that can contain an ultraviolet absorbent in a stable manner and exhibits a superior usability. (In this formula, R denotes a branched or straight chain alkyl group having 8-15 carbon atoms.) (In this formula, R1 and R2 denote, independently of each other, a hydrogen atom or a lower alkyl group having 1-6 carbon atoms, a+b denotes an integer 1-30, and m denotes an integer 10-200.) (In this formula, R1 and R2 denote, independently of each other, a hydrogen atom or a lower alkyl group having 1-6 carbon atoms, a+b denotes an integer 1-30, and n denotes an integer 1-30.)
摘要翻译： 本发明是特征性地含有下述通式（1）表示的苯甲酸烷基酯的皮肤处理组合物。 这提供了在使用时给予清爽感的皮肤处理组合物，并且可以稳定地含有药物和紫外线吸收剂。 另外，本发明是一种防晒油包水型乳化化妆品，其特征在于，含有下述通式（2）或（3）表示的多羟基硬脂酸的酯键，下述通式（1）表示的苯甲酸烷基酯， ，和紫外线吸收剂。 这提供了由油包水型乳化组合物组成的防晒化妆品，其可以稳定地包含紫外线吸收剂并显示出优异的可用性。 （在该式中，R表示碳原子数为8〜15的支链或直链烷基）（式中，R 1，R 2，R 2， 彼此为氢原子或具有1-6个碳原子的低级烷基，a + b表示1-30的整数，m表示10-200的整数。）（在该式中，R 1' SUP>和R 2彼此独立地表示氢原子或具有1-6个碳原子的低级烷基，a + b表示1-30的整数，n表示整数1 -30。）
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公开(公告)号：US07445790B2
公开(公告)日：2008-11-04
申请号：US10513823
申请日：2003-05-07
申请人： Nozomi Oguchi , Reiji Miyahara , Hiroyuki Kakoki , Takayuki Omura
发明人： Nozomi Oguchi , Reiji Miyahara , Hiroyuki Kakoki , Takayuki Omura
IPC分类号： A61K8/02 , A61K31/235
摘要： The present invention is a skin treatment composition that characteristically contains an alkyl benzoate represented by the following general formula (1).This provides a skin treatment composition that gives a refreshing sensation at the time of application and can contain drugs and ultraviolet absorbents in a stable manner.Also, the present invention is a sunblock water-in-oil type emulsified cosmetic characteristically comprising an ester bond product of polyhydroxystearic acid represented by the following general formulas (2) or (3), alkyl benzoate represented by the following general formula (1), and an ultraviolet absorbent.This provides a sunblock cosmetic consisting of a water-in-oil type emulsified composition that can contain an ultraviolet absorbent in a stable manner and exhibits a superior usability. (In this formula, R denotes a branched or straight chain alkyl group having 8-15 carbon atoms.) (In this formula, R1 and R2 denote, independently of each other, a hydrogen atom or a lower alkyl group having 1-6 carbon atoms, a+b denotes an integer 1-30, and m denotes an integer 10-200.) (In this formula, R1 and R2 denote, independently of each other, a hydrogen atom or a lower alkyl group having 1-6 carbon atoms, a+b denotes an integer 1-30, and n denotes an integer 1-30.)
摘要翻译： 本发明是特征性地含有下述通式（1）表示的苯甲酸烷基酯的皮肤处理组合物。 这提供了在使用时给予清爽感的皮肤处理组合物，并且可以稳定地含有药物和紫外线吸收剂。 另外，本发明是一种防晒油包水型乳化化妆品，其特征在于，含有下述通式（2）或（3）表示的聚羟基硬脂酸的酯键，由以下通式（1）表示的苯甲酸烷基酯， ，和紫外线吸收剂。 这提供了由油包水型乳化组合物组成的防晒化妆品，其可以稳定地包含紫外线吸收剂并显示出优异的可用性。 （在该式中，R表示碳原子数为8〜15的支链或直链烷基）（式中，R 1，R 2，R 2， 彼此为氢原子或具有1-6个碳原子的低级烷基，a + b表示1-30的整数，m表示10-200的整数。）（在该式中，R 1' SUP>和R 2彼此独立地表示氢原子或具有1-6个碳原子的低级烷基，a + b表示1-30的整数，n表示整数1 -30。）
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公开(公告)号：US08282910B2
公开(公告)日：2012-10-09
申请号：US12528119
申请日：2008-02-22
申请人： Nozomi Oguchi , Yukie Yoda , Hiroyuki Kakoki
发明人： Nozomi Oguchi , Yukie Yoda , Hiroyuki Kakoki
CPC分类号： A61K8/37 , A61K8/35 , A61K8/40 , A61K2800/59 , A61K2800/592 , A61Q17/04
摘要： The present invention provides a composition for skin or hair which achieves an excellent UV absorption in a wide range of UV wavelength from the UV-A to the UV-B without inhibiting the effect of the alkyl β,β-diphenylacrylate and the α-cyano-β,β-diphenylacrylate (e.g. octocrylene) which serve to improve the photostability of dibenzoylmethane derivative. The composition for skin or hair comprises: (a) a dibenzoylmethane derivative, (b) an alkyl β,β-diphenylacrylate and/or an α-cyano-β,β-diphenylacrylate (e.g. octocrylene), and (c) a specific benzalmalonate derivative (e.g. di(2-ethylhexyl)-4-methoxybenzalmalonate).
摘要翻译： 本发明提供了一种皮肤或头发的组合物，其在从UV-A到UV-B的宽紫外波长范围内具有优异的UV吸收，而不抑制烷基和二苯基丙烯酸酯和α - 氰基 - 和bgr-二苯基丙烯酸酯（例如氰二烯），其用于改善二苯甲酰甲烷衍生物的光稳定性。 用于皮肤或毛发的组合物包括：（a）二苯甲酰甲烷衍生物，（b）丙烯酸烷基酯和/或α-氰基 - 和二苯基丙烯酸酯（例如亚辛基）和（c ）特定的亚苄基丙二酸酯衍生物（例如二（2-乙基己基）-4-甲氧基苯甲醛丙二酸酯）。
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公开(公告)号：US20100221199A1
公开(公告)日：2010-09-02
申请号：US12095713
申请日：2006-12-19
申请人： Hidefumi Araki , Koji Abe , Isao Yajima , Hiroyuki Kakoki , Nozomi Oguchi
发明人： Hidefumi Araki , Koji Abe , Isao Yajima , Hiroyuki Kakoki , Nozomi Oguchi
CPC分类号： A61K8/496 , A61K2800/26 , A61Q17/04
摘要： The present invention is a sunscreen cosmetic comprising 4-(1,1-dimethylethyl)-4′-methoxydibenzoylmethane, a benzotriazole derivative represented by the following general formula (I), and ethylhexyl 2-cyano-3,3-diphenylacrylate.The present invention is a sunscreen cosmetic comprising hexyl diethylaminohydroxybenzoylbenzoate and a benzotriazole derivative represented by the following general formula (I). (In this formula, R′=a straight chain alkyl group of C1-C6 and R″=a straight chain alkyl group of C1-C3.)The object of the present invention is to provide a sunscreen cosmetic that prevents staining due to secondary adhesion to clothing.
摘要翻译： 本发明是包含4-（1,1-二甲基乙基）-4'-甲氧基二苯甲酰甲烷，由以下通式（I）表示的苯并三唑衍生物和2-氰基-3,3-二苯基丙烯酸乙基己酯的防晒化妆品。 本发明是一种包含二乙基氨基羟基苯甲酰基苯甲酸己酯和由以下通式（I）表示的苯并三唑衍生物的防晒化妆品。 （在该式中，R'= C1-C6的直链烷基，R“= C1-C3的直链烷基。）本发明的目的是提供防止二次染色的防晒化妆品 对衣服的粘附。
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公开(公告)号：US20090169494A1
公开(公告)日：2009-07-02
申请号：US11991350
申请日：2006-09-29
申请人： Koji Abe , Nozomi Oguchi , Isao Yajima , Hidefumi Araki , Hiroyuki Kakoki
发明人： Koji Abe , Nozomi Oguchi , Isao Yajima , Hidefumi Araki , Hiroyuki Kakoki
IPC分类号： A61K8/49
CPC分类号： A61K8/4966 , A61K8/496 , A61K8/585 , A61Q17/04
摘要： The present invention is a sunscreen cosmetic comprising 2,4-bis[[4-(2-ethylhexyloxy)-2-hydroxy]phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine and a specific benzotriazole derivative.Also, the present invention is a sunscreen cosmetic comprising a specific benzotriazole derivative and a specific alkylaryl 1,3-propanedione silicone derivative.An object of the present invention is to provide a sunscreen cosmetic that exhibits superior UV-A absorption capacity and excellent stability and also sufficiently dissolves 2,4-bis[[4-(2-ethylhexyloxy)-2-hydroxy]phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine, which has low solubility and crystallizes easily.Another object is to provide a sunscreen cosmetic that can synergistically improve the ultraviolet absorption capacity of conventional ultraviolet absorbents.
摘要翻译： 本发明是包含2,4-双[[4-（2-乙基己氧基）-2-羟基]苯基] -6-（4-甲氧基苯基）-1,3,5-三嗪和特定苯并三唑衍生物的防晒化妆品 。 此外，本发明是包含特定的苯并三唑衍生物和特定的烷基芳基-1,3-丙二酮硅氧烷衍生物的防晒化妆品。 本发明的目的是提供一种防紫外线化妆品，其具有优异的UV-A吸收能力和优异的稳定性，并且还充分溶解2,4-双[[4-（2-乙基己氧基）-2-羟基]苯基] -6 - （4-甲氧基苯基）-1,3,5-三嗪，其溶解度低，结晶容易。 另一个目的是提供可协同地提高常规紫外线吸收剂的紫外线吸收能力的防晒化妆品。
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公开(公告)号：US20100008875A1
公开(公告)日：2010-01-14
申请号：US12528119
申请日：2008-02-22
申请人： Nozomi Oguchi , Yukie Yoda , Hiroyuki Kakoki
发明人： Nozomi Oguchi , Yukie Yoda , Hiroyuki Kakoki
CPC分类号： A61K8/37 , A61K8/35 , A61K8/40 , A61K2800/59 , A61K2800/592 , A61Q17/04
摘要： The present invention provides a composition for skin or hair which achieves an excellent UV absorption in a wide range of UV wavelength from the UV-A to the UV-B without inhibiting the effect of the alkyl β,β-diphenylacrylate and the α-cyano-β,β-diphenylacrylate (e.g. octocrylene) which serve to improve the photostability of dibenzoylmethane derivative. The composition for skin or hair comprises: (a) a dibenzoylmethane derivative, (b) an alkyl β,β-diphenylacrylate and/or an α-cyano-β,β-diphenylacrylate (e.g. octocrylene), and (c) a specific benzalmalonate derivative (e.g. di(2-ethylhexyl)-4-methoxybenzalmalonate).
摘要翻译： 本发明提供一种用于皮肤或毛发的组合物，其在从UV-A到UV-B的宽紫外波长范围内具有优异的UV吸收，而不抑制烷基β，β-二苯基丙烯酸酯和α-氰基 -β-二苯基丙烯酸酯（例如，辛酸钠），其用于改善二苯甲酰甲烷衍生物的光稳定性。 用于皮肤或头发的组合物包括：（a）二苯甲酰甲烷衍生物，（b）β，β-二苯基丙烯酸烷基酯和/或α-氰基-β-二苯基丙烯酸酯（例如，辛格林），和（c）特定的亚苄基丙二酸 衍生物（例如二（2-乙基己基）-4-甲氧基苯甲醛丙二酸酯）。
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