公开(公告)号：US20240358803A1

公开(公告)日：2024-10-31

申请号：US18767447

申请日：2024-07-09

Applicant: Nutramax Laboratories, Inc.

Inventor： Brian Cornblatt ,  Grace Cornblatt ,  Anton Bzhelyansky ,  Robert Henderson

IPC: A61K38/47 ,  A23L33/105 ,  A61K9/00 ,  A61K9/14 ,  A61K9/28 ,  A61K31/19 ,  A61K31/194 ,  A61K31/26 ,  A61K31/357 ,  A61K31/375 ,  A61K31/7028 ,  A61K31/716 ,  A61K33/06 ,  A61K36/06 ,  A61K36/07 ,  A61K36/28 ,  A61K36/31 ,  A61K45/06 ,  A61K47/42 ,  A61P3/06

CPC classification number: A61K38/47 ,  A23L33/105 ,  A61K9/0053 ,  A61K9/14 ,  A61K9/28 ,  A61K31/19 ,  A61K31/194 ,  A61K31/26 ,  A61K31/357 ,  A61K31/375 ,  A61K31/7028 ,  A61K31/716 ,  A61K33/06 ,  A61K36/06 ,  A61K36/07 ,  A61K36/28 ,  A61K36/31 ,  A61K45/06 ,  A61K47/42 ,  A61P3/06 ,  C12Y302/01147 ,  A23V2002/00

Abstract: The present disclosure relates to the synergistic combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, a cofactor of the enzyme, and a glucan. The present disclosure also relates to the synergistic combination of sulforaphane or a derivative thereof and a glucan. The present disclosure also relates to the synergistic combination of a broccoli extract or powder and a glucan. The glucan may be a β-glucan. The glucan may be provided in a mushroom extract or powder selected from one or more of a maitake, a shiitake, or a reishi mushroom. Compositions and methods relating to these combinations are described.

公开(公告)号：US11654186B2

公开(公告)日：2023-05-23

申请号：US16701644

申请日：2019-12-03

Applicant: NUTRAMAX LABORATORIES, INC.

Inventor： Brian Cornblatt ,  Grace Cornblatt ,  Anton Bzhelyansky ,  Robert Henderson

IPC: A61K31/716 ,  A61K31/095 ,  A61K36/064 ,  A61K36/31 ,  A61K36/07 ,  A61K38/47 ,  A23L33/105 ,  A61K31/375 ,  A61K31/7028 ,  A61K33/06 ,  A61K9/14 ,  A61P3/06 ,  A61K31/26 ,  A61K45/06 ,  A61K9/00 ,  A61K9/28 ,  A61K31/194 ,  A61K47/42 ,  A61K31/19 ,  A61K36/28 ,  A61K36/06 ,  A61K31/357

CPC classification number: A61K38/47 ,  A23L33/105 ,  A61K9/0053 ,  A61K9/14 ,  A61K9/28 ,  A61K31/19 ,  A61K31/194 ,  A61K31/26 ,  A61K31/357 ,  A61K31/375 ,  A61K31/7028 ,  A61K31/716 ,  A61K33/06 ,  A61K36/06 ,  A61K36/07 ,  A61K36/28 ,  A61K36/31 ,  A61K45/06 ,  A61K47/42 ,  A61P3/06 ,  C12Y302/01147 ,  A23V2002/00 ,  A61K2300/00 ,  A61K38/47 ,  A61K2300/00 ,  A61K31/375 ,  A61K2300/00 ,  A61K31/26 ,  A61K2300/00 ,  A61K36/28 ,  A61K2300/00 ,  A61K36/06 ,  A61K2300/00 ,  A61K36/07 ,  A61K2300/00

Abstract: The present disclosure relates to the synergistic combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, a cofactor of the enzyme, and a glucan. The present disclosure also relates to the synergistic combination of sulforaphane or a derivative thereof and a glucan. The present disclosure also relates to the synergistic combination of a broccoli extract or powder and a glucan. The glucan may be a β-glucan. The glucan may be provided in a mushroom extract or powder selected from one or more of a maitake, a shiitake, or a reishi mushroom. Compositions and methods relating to these combinations are described.

公开(公告)号：US20210008176A1

公开(公告)日：2021-01-14

申请号：US17007067

申请日：2020-08-31

Applicant: NUTRAMAX LABORATORIES, INC.

Inventor： Brian Cornblatt ,  Grace Cornblatt ,  Anton Bzhelyansky ,  Robert Henderson ,  Ronald Kettenacker

IPC: A61K38/47 ,  A23L33/105 ,  A61K36/31 ,  A61K31/375 ,  A61K31/7028 ,  A61K33/06 ,  A61K9/14 ,  A61P3/06 ,  A61K31/26 ,  A61K36/07 ,  A61K45/06 ,  A61K9/00 ,  A61K9/28 ,  A61K31/194 ,  A61K47/42 ,  A61K31/19 ,  A61K36/28 ,  A61K31/716 ,  A61K36/06 ,  A61K31/357

Abstract: The invention relates to the combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, an enzyme potentiator, and magnesium or a salt or complex thereof. The invention also relates to the combination of a sulforaphane or a derivative thereof and magnesium or a salt or complex thereof. The invention also relates to the combination of a broccoli extract or powder and magnesium or a salt or complex thereof. The invention provides compositions and methods relating to these combinations.

公开(公告)号：US09421183B2

公开(公告)日：2016-08-23

申请号：US14586765

申请日：2014-12-30

Applicant: Nutramax Laboratories, Inc.

Inventor： Brian Cornblatt ,  Grace Cornblatt ,  Anton Bzhelyansky ,  Robert Henderson

IPC: A61K31/095 ,  A61K36/07 ,  A61K36/31 ,  A61K31/26 ,  A61K38/47 ,  A61K31/375 ,  A61K31/7028 ,  A61K33/06 ,  A61K45/06 ,  A61K9/00 ,  A61K9/28 ,  A61K31/194 ,  A61K47/42 ,  A61K31/19 ,  A61K36/28 ,  A61K31/716 ,  A61K36/06 ,  A23L1/30 ,  A61K31/357

CPC classification number: A61K38/47 ,  A23L33/105 ,  A23V2002/00 ,  A61K9/0053 ,  A61K9/14 ,  A61K9/28 ,  A61K31/19 ,  A61K31/194 ,  A61K31/26 ,  A61K31/357 ,  A61K31/375 ,  A61K31/7028 ,  A61K31/716 ,  A61K33/06 ,  A61K36/06 ,  A61K36/07 ,  A61K36/28 ,  A61K36/31 ,  A61K45/06 ,  A61K47/42 ,  C12Y302/01147 ,  A61K2300/00

Abstract: The invention relates to the combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, an enzyme potentiator, and a mushroom (preferably maitake, shiitake, or reishi mushroom) extract or powder. The invention also relates to the combination of sulforaphane or a derivative thereof and a mushroom (preferably maitake, shiitake, or reishi mushroom) extract or powder. The present invention also relates to the combination of a broccoli extract or powder and a mushroom (preferably maitake, shiitake, or reishi mushroom) extract or powder. The present provides compositions and methods relating to these combinations.

Abstract translation: 本发明涉及萝卜硫素前体，能够将萝卜硫素前体转化为萝卜硫素的酶，酶增效剂，以及蘑菇（优选麦片，香菇或雷氏蘑菇）提取物或粉末的组合。 本发明还涉及萝卜硫素或其衍生物和蘑菇（优选茅草，香菇或雷氏蘑菇）提取物或粉末的组合。 本发明还涉及一种将花椰菜提取物或粉末与蘑菇（优选麦片，香菇或雷氏蘑菇）提取物或粉末的组合。 本发明提供了与这些组合有关的组合物和方法。

公开(公告)号：US20150174213A1

公开(公告)日：2015-06-25

申请号：US14412180

申请日：2013-07-03

Applicant: Nutramax Laboratories, Inc.

Inventor： Brian Cornblatt ,  Grace Cornblatt ,  Anton Bzhelyansky ,  Robert Henderson

IPC: A61K38/47 ,  A61K31/7028 ,  A61K45/06 ,  A61K31/375 ,  A61K31/26 ,  A61K36/31 ,  A61K31/19

CPC classification number: A61K38/47 ,  A23L33/105 ,  A23V2002/00 ,  A61K9/0053 ,  A61K9/14 ,  A61K9/28 ,  A61K31/19 ,  A61K31/194 ,  A61K31/26 ,  A61K31/357 ,  A61K31/375 ,  A61K31/7028 ,  A61K31/716 ,  A61K33/06 ,  A61K36/06 ,  A61K36/07 ,  A61K36/28 ,  A61K36/31 ,  A61K45/06 ,  A61K47/42 ,  A61P3/06 ,  C12Y302/01147 ,  A61K2300/00

Abstract: The invention relates to the combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, an enzyme potentiator, and ursolic acid, a salt, ester, amide, or derivative thereof. The invention also relates to the combination of a sulforaphane or a derivative thereof and ursolic acid, a salt, ester, amide, or derivative thereof. The invention also relates to the combination of a broccoli extract or powder and ursolic acid, a salt, ester, amide, or derivative thereof. The invention provides compositions and methods relating to these combinations.

公开(公告)号：US20220118062A1

公开(公告)日：2022-04-21

申请号：US17560494

申请日：2021-12-23

Applicant: Nutramax Laboratories, Inc.

Inventor： Brian Cornblatt ,  Grace Cornblatt ,  Anton Bzhelyansky ,  Robert Henderson

IPC: A61K38/47 ,  A61K31/19 ,  A61K47/42 ,  A61K36/07 ,  A61K36/06 ,  A61K31/357 ,  A61K9/14 ,  A61K31/716 ,  A61K36/28 ,  A61K9/00 ,  A61K31/375 ,  A23L33/105 ,  A61P3/06 ,  A61K9/28 ,  A61K31/7028 ,  A61K33/06 ,  A61K36/31 ,  A61K31/194 ,  A61K31/26 ,  A61K45/06

Abstract: The invention relates to the combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, an enzyme potentiator, and a milk thistle extract or powder. The invention also relates to the combination of a sulforaphane or a derivative thereof and a milk thistle extract or powder. The invention also relates to the combination of a broccoli extract or powder and a milk thistle extract or powder. The invention provides compositions and methods relating to these combinations.

公开(公告)号：US11224639B2

公开(公告)日：2022-01-18

申请号：US16865529

申请日：2020-05-04

Applicant: Nutramax Laboratories, Inc.

Inventor： Brian Cornblatt ,  Grace Cornblatt ,  Anton Bzhelyansky ,  Robert Henderson

IPC: A61K38/47 ,  A23L33/105 ,  A61K36/31 ,  A61K31/375 ,  A61K31/7028 ,  A61K33/06 ,  A61K9/14 ,  A61P3/06 ,  A61K31/26 ,  A61K36/07 ,  A61K45/06 ,  A61K9/00 ,  A61K9/28 ,  A61K31/194 ,  A61K47/42 ,  A61K31/19 ,  A61K36/28 ,  A61K31/716 ,  A61K36/06 ,  A61K31/357

Abstract: The invention relates to the combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, an enzyme potentiator, and a milk thistle extract or powder. The invention also relates to the combination of a sulforaphane or a derivative thereof and a milk thistle extract or powder. The invention also relates to the combination of a broccoli extract or powder and a milk thistle extract or powder. The invention provides compositions and methods relating to these combinations.

公开(公告)号：US10583178B2

公开(公告)日：2020-03-10

申请号：US15244374

申请日：2016-08-23

Applicant: NUTRAMAX LABORATORIES, INC.

Inventor： Brian Cornblatt ,  Grace Cornblatt ,  Anton Bzhelyansky ,  Robert Henderson

IPC: A61K31/716 ,  A61K31/095 ,  A61K36/064 ,  A61K36/31 ,  A61K36/07 ,  A61K38/47 ,  A23L33/105 ,  A61K31/375 ,  A61K31/7028 ,  A61K33/06 ,  A61K9/14 ,  A61P3/06 ,  A61K31/26 ,  A61K45/06 ,  A61K9/00 ,  A61K9/28 ,  A61K31/194 ,  A61K47/42 ,  A61K31/19 ,  A61K36/28 ,  A61K36/06 ,  A61K31/357

Abstract: The present disclosure relates to the synergistic combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, a cofactor of the enzyme, and a glucan. The present disclosure also relates to the synergistic combination of sulforaphane or a derivative thereof and a glucan. The present disclosure also relates to the synergistic combination of a broccoli extract or powder and a glucan. The glucan may be a β-glucan. The glucan may be provided in a mushroom extract or powder selected from one or more of a maitake, a shiitake, or a reishi mushroom. Compositions and methods relating to these combinations are described.

公开(公告)号：US20150118305A1

公开(公告)日：2015-04-30

申请号：US14586698

申请日：2014-12-30

Applicant: Nutramax Laboratories, Inc.

Inventor： Brian Cornblatt ,  Grace Cornblatt ,  Anton Bzhelyansky ,  Robert Henderson

IPC: A61K38/47 ,  A61K36/31 ,  A61K31/19 ,  A61K9/28 ,  A61K31/7028 ,  A61K31/375

CPC classification number: A61K38/47 ,  A23L33/105 ,  A23V2002/00 ,  A61K9/0053 ,  A61K9/14 ,  A61K9/28 ,  A61K31/19 ,  A61K31/194 ,  A61K31/26 ,  A61K31/357 ,  A61K31/375 ,  A61K31/7028 ,  A61K31/716 ,  A61K33/06 ,  A61K36/06 ,  A61K36/07 ,  A61K36/28 ,  A61K36/31 ,  A61K45/06 ,  A61K47/42 ,  A61P3/06 ,  C12Y302/01147 ,  A61K2300/00

Abstract: The invention relates to the combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, an enzyme potentiator, and ursolic acid, a salt, ester, amide, or derivative thereof. The invention also relates to the combination of a sulforaphane or a derivative thereof and ursolic acid, a salt, ester, amide, or derivative thereof. The invention also relates to the combination of a broccoli extract or powder and ursolic acid, a salt, ester, amide, or derivative thereof. The invention provides compositions and methods relating to these combinations.

Abstract translation: 本发明涉及萝卜硫素前体，能够将萝卜硫素前体转化为萝卜硫素的酶，酶增效剂和熊果酸，其盐，酯，酰胺或其衍生物的组合。 本发明还涉及萝卜硫素或其衍生物与熊果酸，其盐，酯，酰胺或其衍生物的组合。 本发明还涉及西兰花提取物或粉末与熊果酸，其盐，酯，酰胺或其衍生物的组合。 本发明提供了与这些组合有关的组合物和方法。

公开(公告)号：US20150118304A1

公开(公告)日：2015-04-30

申请号：US14586711

申请日：2014-12-30

Applicant: Nutramax Laboratories, Inc.

Inventor： Brian CORNBLATT ,  Grace Cornblatt ,  Anton Bzhelyansky ,  Robert Henderson ,  Ronald Kettenacker

IPC: A61K31/26 ,  A61K9/00 ,  A61K33/06 ,  A61K45/06 ,  A61K36/31 ,  A61K31/194 ,  A61K47/42 ,  A61K9/28

CPC classification number: A61K38/47 ,  A23L33/105 ,  A23V2002/00 ,  A61K9/0053 ,  A61K9/14 ,  A61K9/28 ,  A61K31/19 ,  A61K31/194 ,  A61K31/26 ,  A61K31/357 ,  A61K31/375 ,  A61K31/7028 ,  A61K31/716 ,  A61K33/06 ,  A61K36/06 ,  A61K36/07 ,  A61K36/28 ,  A61K36/31 ,  A61K45/06 ,  A61K47/42 ,  A61P3/06 ,  C12Y302/01147 ,  A61K2300/00

Abstract: The invention relates to the combination of a sulforaphane precursor, an enzyme capable of converting the sulforaphane precursor to sulforaphane, an enzyme potentiator, and magnesium or a salt or complex thereof. The invention also relates to the combination of a sulforaphane or a derivative thereof and magnesium or a salt or complex thereof. The invention also relates to the combination of a broccoli extract or powder and magnesium or a salt or complex thereof. The invention provides compositions and methods relating to these combinations.