公开(公告)号：US20160312188A1

公开(公告)日：2016-10-27

申请号：US14998446

申请日：2016-01-08

Applicant: OSAKA UNIVERSITY

Inventor： Akifumi Matsuyama ,  Hiroshi Komoda ,  Yoshiki Sawa ,  Yuzuru Kanakura

IPC: C12N5/071 ,  C12N5/077 ,  C12N5/0775

CPC classification number: C12N5/0676 ,  A61K35/12 ,  C12N5/0653 ,  C12N5/0667 ,  C12N5/0678 ,  C12N2500/25 ,  C12N2500/32 ,  C12N2500/33 ,  C12N2500/38 ,  C12N2501/115 ,  C12N2501/335 ,  C12N2503/02 ,  C12N2506/1384 ,  C12N2533/52 ,  G01N33/507

Abstract: A method of obtaining pancreatic endocrine cells from cells originating in an adipose tissue characterized by comprising culturing the adipose tissue-origin cells; the pancreatic endocrine cells that can be obtained thereby; a method of treating or preventing a disease caused by the hypofunction in pancreatic endocrine cells wherein the above-described pancreatic endocrine cells are used; a method of screening a substance capable of promoting or inhibiting the differentiation into pancreatic endocrine cells characterized by comprising adding a candidate substance to a medium in the course of culturing adipose tissue-origin cells to obtain the pancreatic endocrine cells; and so on.