公开(公告)号：US20230192931A1

公开(公告)日：2023-06-22

申请号：US16490090

申请日：2018-03-01

Applicant: Osaka University

Inventor： Akira Harada ,  Hiroyasu Yamaguchi ,  Yoshinori Takashima ,  Suguru Nomimura ,  Hikaru Aramoto ,  Ryohei Ikura ,  Yuichiro Kobayashi ,  Yukie Nakamitsu

IPC: C08F251/00 ,  C08B37/16

CPC classification number: C08F251/00 ,  C08B37/0012 ,  C08F2800/10

Abstract: Provided are a host-group-containing polymerizable monomer usable as a starting material for producing a macromolecular material with a high degree of freedom in material design, and excellent toughness and strength; a macromolecular material produced using the host-group-containing polymerizable monomer; and a method for producing the macromolecular material. The host-group-containing polymerizable monomer according to the present invention is a host-group-containing polymerizable monomer, and the host group is a monovalent group formed by removing one hydrogen atom or hydroxy group from a cyclodextrin derivative. The cyclodextrin derivative has such a structure that the hydrogen atom of at least one hydroxy group of a cyclodextrin is replaced with a group selected from the group consisting of a hydrocarbon group, an acyl group, and —CONHR wherein R represents a methyl group or an ethyl group.

公开(公告)号：US20190225936A1

公开(公告)日：2019-07-25

申请号：US16320622

申请日：2017-07-25

Applicant: Osaka University ,  Kyoto University

Inventor： Akira Harada ,  Yoshinori Takashima ,  Masaki Nakahata ,  Motomu Tanaka ,  Marcel Hoerning

IPC: C12N5/00

Abstract: Provided are: a polymer gel for a medium, and a medium in which the stiffness of the polymer gel can be easily and reversibly changed and the shape of cells can be controlled according to the stiffness of the gel; and a method for culturing cells using the medium. The polymer gel for a medium contains a solvent and a crosslinked structure that is crosslinked by reversible bonds. The stiffness of the polymer gel for a medium can be easily and reversibly changed. Accordingly, when the polymer gel for a medium according to the present invention is used, cell morphology and function can be reversibly controlled according to the stiffness of the gel.

公开(公告)号：US10174172B2

公开(公告)日：2019-01-08

申请号：US14914455

申请日：2014-08-27

Applicant: Osaka University

Inventor： Akira Harada ,  Hiroyasu Yamaguchi ,  Akihito Hashidzume ,  Yoshinori Takashima ,  Tomoko Sekine ,  Yuichiro Kobayashi ,  Masaki Nakahata

IPC: C08G81/02 ,  C08J5/12 ,  C12N9/96 ,  C09J5/00

Abstract: The present invention provides a joined body with no risk of detachment from the joining surface without using an adhesive, and a method for producing the joined body. The present invention also provides a reversible joined body that enables control of joining and dissociation, and a method for producing the reversible joined body. In the joined body, a chemical bond is formed between two or more same or different solid-state materials at their contact interfaces by a chemical reaction.

公开(公告)号：US20180133986A1

公开(公告)日：2018-05-17

申请号：US15564083

申请日：2016-04-08

Applicant: Osaka University

Inventor： Akira Harada ,  Yoshinori Takashima ,  Masaki Nakahata

IPC: B29C73/18 ,  C08F2/10 ,  C08F2/46 ,  C08F16/02 ,  C08F22/10 ,  C08F22/38

CPC classification number: B29C73/18 ,  C08F2/10 ,  C08F2/46 ,  C08F4/40 ,  C08F16/02 ,  C08F22/105 ,  C08F22/38 ,  C08F220/58 ,  C08L33/26 ,  C08F220/54 ,  C08F220/56

Abstract: The present invention provides a self-repairing material having self-repairing properties and shape memory properties, as well as high dynamic strength, and also provides a method for manufacturing the same. The self-repairing material of the present invention comprises a polymer comprising specific monomer units in specific ratios, and the concentration of the monomer units is within a specific range.

公开(公告)号：US20170233533A1

公开(公告)日：2017-08-17

申请号：US15322826

申请日：2015-06-19

Applicant: Osaka University

Inventor： Akira Harada ,  Yoshinori Takashima ,  Yuichiro Kobayashi ,  Masaki Nakahata ,  Shoko Mori

IPC: C08G83/00

CPC classification number: C08G83/007 ,  C08G65/33306 ,  C08G65/3346 ,  C08G65/337 ,  C08L101/00

Abstract: Provided is a self-restoring macromolecular material that not only has excellent stress relaxation but that can also be easily restored to its original state, even when damaged or severed. Also provided is a method for producing the self-restoring macromolecular material. The self-restoring macromolecular material contains a crosslinked structure that is formed by crosslinking a polymer containing at least a polyrotaxane molecule. The polyrotaxane molecule is formed so as to include a cyclic molecule 21 and a linear molecule that passes through an opening 21a of the cyclic molecule. The crosslinked structure 1 is crosslinked via a reversible bond between the cyclic molecule of the polyrotaxane molecule and a polymer molecule other than the polyrotaxane molecule.

公开(公告)号：US20250136762A1

公开(公告)日：2025-05-01

申请号：US18684206

申请日：2022-08-19

Applicant: OSAKA UNIVERSITY ,  YUSHIRO CHEMICAL INDUSTRY CO., LTD.

Inventor： Yoshinori Takashima ,  Akira Harada ,  Motofumi Osaki ,  Junsu Park ,  Ryohei Ikura ,  Changming Jin ,  Hidenori Shirakawa ,  Yujiro Kitamura

IPC: C08G75/02

Abstract: The present invention provides a host group-containing polymerizable monomer that can be used as a raw material for producing a macromolecular material having excellent toughness and strength, and a method for producing the same, as well as a macromolecular material produced by using the host group-containing polymerizable monomer, and a method for producing the same. The present invention provides a host group-containing polymerizable monomer, the host group-containing polymerizable monomer having a sulfide group, the host group being a monovalent group formed by removing one hydrogen atom or hydroxy group from a cyclodextrin derivative, and the cyclodextrin derivative having a structure formed such that a hydrogen atom of at least one hydroxy group contained in a cyclodextrin is replaced with at least one group selected from the group consisting of a hydrocarbon group, an acyl group, and —CONHR wherein R represents a methyl group or an ethyl group.

公开(公告)号：US11535691B2

公开(公告)日：2022-12-27

申请号：US16086088

申请日：2017-02-28

Applicant: Osaka University

Inventor： Akira Harada ,  Yoshinori Takashima ,  Kazuhisa Iwaso

IPC: C08F220/58 ,  C08B37/00 ,  C08F2/10 ,  C08B37/16

Abstract: Provided are a macromolecular material that exhibits high toughness and self-healing properties, and that can be produced by a simple process, as well as a method for producing the material. The macromolecular material contains a crosslinked polymer crosslinked by the interaction between a host group and a guest group. The crosslinked polymer contains a repeating structural unit represented by the following formula (1a) and a repeating structural unit represented by the following formula (2a).

公开(公告)号：US20220332859A1

公开(公告)日：2022-10-20

申请号：US17641088

申请日：2020-09-04

Applicant: Osaka University

Inventor： Yoshinori Takashima ,  Akira Harada ,  Hiroyasu Yamaguchi ,  Motofumi Osaki ,  Ryohei Ikura ,  Hiroki Tamura

IPC: C08F20/56 ,  C08F12/08 ,  C08F20/06

Abstract: Provided are a macromolecular material comprising two or more types of polymers, which are less likely to be separated, and having excellent mechanical properties, a method for producing the same, and a macromolecular compatibilizing agent. The macromolecular material according to the present invention comprises a first macromolecular compound having a ring host group, and a second macromolecular compound free of the host group, and the second macromolecular compound penetrates through the ring of the host group in a skewering manner. The method for producing the macromolecular material according to the present invention comprises polymerizing a polymerizable monomer in the presence of the first macromolecular compound. The macromolecular compatibilizing agent according to the present invention comprises a macromolecular compound having a ring host group.

公开(公告)号：US20210155731A1

公开(公告)日：2021-05-27

申请号：US16612046

申请日：2018-05-11

Applicant: Osaka University

Inventor： Akira Harada ,  Hiroyasu Yamaguchi ,  Yoshinori Takashima ,  Tomoko Tokuhara ,  Suguru Nomimura ,  Hikaru Aramoto ,  Ryohei Ikura ,  Nanami Okano

IPC: C08F220/58

Abstract: Provided are a composition for polymerization from which a macromolecular material that contains a host-group-introduced polymer with excellent energy to failure can be produced without using a solvent; a polymer of the composition; and a method for producing the polymer. The composition for polymerization contains a solution containing a first polymerizable compound and a host-group-containing polymerizable compound that is dissolved in the first polymerizable compound, wherein the host group present in the host-group-containing polymerizable compound is a group formed by removing one hydrogen atom or hydroxy group from a cyclodextrin, and wherein the cyclodextrin is at least one cyclodextrin selected from the group consisting of α-cyclodextrin, β-cyclodextrin, and γ-cyclodextrin.

公开(公告)号：US10669457B2

公开(公告)日：2020-06-02

申请号：US15863047

申请日：2018-01-05

Applicant: Osaka University ,  Toyota Jidosha Kabushiki Kaisha

Inventor： Akira Harada ,  Yoshinori Takashima ,  Tomoko Tokuhara ,  Yasushi Shojima ,  Ayako Sakawaki ,  Takeshi Sekito ,  Hiroaki Takahashi

IPC: C09J133/10 ,  C09J5/02 ,  B32B7/12 ,  C09D133/06 ,  C09D133/26 ,  C08G83/00

Abstract: The present invention provides an adhered structure in which members of the same or different materials are adhered to each other with a high adhesive strength and a method for producing the adhered structure. The adhered structure of the present invention comprises a first solid member, a second solid member, and an adhesive member. The first solid member and the second solid member are adhered to each other through the adhesive member. The adhesive member contains a polymer. The polymer is chemically bonded to the first solid member and the second solid member.