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公开(公告)号:US20150336876A1
公开(公告)日:2015-11-26
申请号:US14761897
申请日:2014-01-21
Applicant: OSAKA UNIVERSITY , KNC LABORATORIES CO., LTD.
Inventor: Yoshikatsu KANAI , Shushi NAGAMORI , Yoshihiko KITAURA , Masahiro NEYA , Naohiro MATSUSHITA
IPC: C07C217/48 , C07D333/20 , C07D277/28 , C07C217/72 , C07D215/233 , C07D213/68 , C07C255/54 , C07C255/37 , C07D215/26 , C07D209/48 , C07D401/12 , C07D409/06 , C07D405/06 , C07D417/06 , C07D413/06 , C07C271/16
CPC classification number: C07C217/48 , C07C211/09 , C07C217/04 , C07C217/72 , C07C255/37 , C07C255/54 , C07C271/16 , C07C271/20 , C07C317/22 , C07C317/28 , C07C323/20 , C07C323/25 , C07D209/48 , C07D213/68 , C07D215/22 , C07D215/233 , C07D215/26 , C07D263/32 , C07D277/28 , C07D295/08 , C07D307/52 , C07D333/20 , C07D401/12 , C07D403/12 , C07D405/04 , C07D405/06 , C07D409/04 , C07D409/06 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06
Abstract: The invention provides a compound having a selective inhibitory activity against highly-expressed LAT-1 in tumor cell. The compound is represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof, and a LAT-1 inhibitor comprising the same.
Abstract translation: 本发明提供对肿瘤细胞中高表达LAT-1具有选择性抑制活性的化合物。 化合物由式(I)表示:其中每个符号如说明书中所定义,或其盐,和含有该化合物的LAT-1抑制剂。