利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

5 条记录 (耗时 0.039 秒)

    PEPTIDE CAPABLE OF BINDING TO IMMUNOGLOBULIN
    1.
    发明申请
    PEPTIDE CAPABLE OF BINDING TO IMMUNOGLOBULIN 审中-公开
    能够与免疫球蛋白结合的肽

    公开(公告)号：US20130225508A1

    公开(公告)日：2013-08-29

    申请号：US13877001

    申请日：2011-09-22

    申请人： Osamu Masaki ,  Tetsuya Tomita

    发明人： Osamu Masaki ,  Tetsuya Tomita

    IPC分类号： C07K7/06

    CPC分类号： C07K7/06 ,  A61K38/00 ,  C07K2319/00

    摘要： The present invention relates to a peptide capable of binding to an immunoglobulin, and to a fusion protein containing such a peptide. The present invention also relates to a pharmaceutical composition for the treatment or prevention of a disease caused by binding between C1q and an immunoglobulin, which comprises a peptide capable of binding to the immunoglobulin or a fusion protein with such a peptide, and to the like. The pharmaceutical composition provided by the present invention is effective particularly in treating arthritis and rheumatism.

    摘要翻译： 本发明涉及能够结合免疫球蛋白的肽和含有这种肽的融合蛋白。 本发明还涉及用于治疗或预防由C1q与免疫球蛋白结合引起的疾病的药物组合物，其包含能够与该免疫球蛋白结合的肽或与该肽结合的融合蛋白等。 本发明提供的药物组合物特别是在治疗关节炎和风湿病方面是有效的。

    MEDICAMENT COMPRISING HGF GENE
    2.
    发明申请
    MEDICAMENT COMPRISING HGF GENE 审中-公开
    包含HGF基因的药物

    公开(公告)号：US20090004260A1

    公开(公告)日：2009-01-01

    申请号：US12203661

    申请日：2008-09-03

    申请人： Ryuichi MORISHITA ,  Toshio Ogihara ,  Toshikazu Nakamura ,  Tetsuya Tomita ,  Takahiro Ochi

    发明人： Ryuichi MORISHITA ,  Toshio Ogihara ,  Toshikazu Nakamura ,  Tetsuya Tomita ,  Takahiro Ochi

    IPC分类号： A61K9/127 ,  A61K31/7088 ,  A61P9/00

    CPC分类号： A61K9/1271 ,  A61K9/1272 ,  A61K38/1833 ,  A61K48/00

    摘要： The present invention relates to a method for treating insufficiency of peripheral circulation or peripheral angiostenosis in a subject for which HGF is effective, comprising administering to the area affected by the insufficiency of peripheral circulation or peripheral angiostenosis a therapeutically effective amount of an expression vector containing a constitutive promoter operably linked to a HGF coding sequence, whereby the HGF is expressed, promoting the growth of vascular endothelial cells but not vascular smooth muscle cells.

    摘要翻译： 本发明涉及一种用于治疗HGF有效的受试者的外周循环不足或周围血管狭窄的方法，包括对受周围循环不足或周围血管狭窄影响的区域施用治疗有效量的含有 与HGF编码序列可操作地连接的组成型启动子，由此表达HGF，促进血管内皮细胞的生长而不是血管平滑肌细胞。

    Decoy composition for treating and preventing inflammatory disease
    5.
    发明申请
    Decoy composition for treating and preventing inflammatory disease 审中-公开
    用于治疗和预防炎性疾病的诱饵组合物

    公开(公告)号：US20060241066A1

    公开(公告)日：2006-10-26

    申请号：US10516208

    申请日：2003-05-20

    申请人： Tetsuya Tomita ,  Hideki Yoshikawa ,  Ryuichi Morishita

    发明人： Tetsuya Tomita ,  Hideki Yoshikawa ,  Ryuichi Morishita

    IPC分类号： A61K48/00 ,  A61K9/127

    CPC分类号： A61K31/7088 ,  A61K38/1709 ,  A61K48/005

    摘要： It is intended to efficiently treat an inflammatory disease without causing side effects. This object can be achieved by providing a medicinal composition for treating and preventing an inflammatory disease and disorders, and disorders caused by the disease and disorders which contains at least one decoy of NF-κB or an analogous transcriptional factor and a pharmaceutically acceptable carrier; and a method of treating and preventing an inflammatory disease and disorders, and disorders caused by the disease and disorders which comprises the step of administering to a patient a composition containing at least one decoy of NF-κB or an analogous transcriptional factor and a pharmaceutically acceptable carrier.

    摘要翻译： 旨在有效地治疗炎性疾病而不引起副作用。 该目的可以通过提供一种用于治疗和预防炎性疾病和病症的药物组合物，以及由包含至少一种NF-κB诱变物或类似转录因子和药学上可接受的载体的疾病和病症引起的疾病， 以及治疗和预防炎性疾病和病症以及由疾病和病症引起的疾病的方法，其包括向患者施用含有至少一种NF-κB诱变物或类似转录因子和药学上可接受的组合物的步骤 载体