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30 条记录 (耗时 0.024 秒)

    Method and apparatus for analysis by liquid chromatography
    7.
    发明授权
    Method and apparatus for analysis by liquid chromatography 有权
    用于液相色谱分析的方法和装置

    公开(公告)号：US08104330B2

    公开(公告)日：2012-01-31

    申请号：US12278867

    申请日：2006-02-09

    申请人： Morimasa Hayashi ,  Yoshihiro Hayakawa

    发明人： Morimasa Hayashi ,  Yoshihiro Hayakawa

    IPC分类号： G01N30/30

    CPC分类号： G01N30/30 ,  G01N30/34 ,  G01N2030/3007 ,  G01N2030/347

    摘要： In order to obtain a temperature gradient elution method which is rapid and accurate, a mobile phase (1) is supplied through two mobile-phase flow channels (2a) and (2b), mixed together, and introduced into the column (15) while the column (15) is made adiabatic. In this operation, the temperature of the mobile phase in one mobile-phase flow channel, i.e., the channel (2a), is regulated to a constant temperature higher than the upper limit of the target temperature range to be obtained in the column (15), while the temperature of the mobile phase in the other mobile-phase flow channel, i.e., the channel (2b), is regulated to a constant temperature lower than the lower limit of the target temperature range in the column (15). By controlling the flow rates in the two mobile-phase flow channels (2a) and (2b), the proportion in which these mobile-phase portions are mixed is changed with time to thereby change the temperature of the mobile phase in the column (15) with time. The temperature gradient elution method is thus conducted.

    摘要翻译： 为了获得快速准确的温度梯度洗脱方法，将流动相（1）通过两个流动相流动通道（2a）和（2b）供应，混合在一起，并引入塔（15），同时 柱（15）是绝热的。 在该操作中，一个流动相流路（即，通道（2a））中的流动相的温度被调节到高于在列（15）中获得的目标温度范围的上限的恒定温度 ），而另一流动相流路（即，通道（2b））中的流动相的温度被调节到低于列（15）中的目标温度范围的下限的恒定温度。 通过控制两个流动相流动通道（2a）和（2b）中的流速，混合这些流动相部分的比例随时间而改变，从而改变塔（15）中流动相的温度 ） 随着时间的推移。 因此进行温度梯度洗脱法。

    Apparatus for processing record-structured data by inserting replacement data of arbitrary length into selected data fields
    8.
    发明授权
    Apparatus for processing record-structured data by inserting replacement data of arbitrary length into selected data fields 失效
    用于通过将任意长度的替换数据插入所选数据字段来处理记录结构数据的装置

    公开(公告)号：US5081608A

    公开(公告)日：1992-01-14

    申请号：US339769

    申请日：1989-04-18

    申请人： Noboru Tamura ,  Yoshihiro Hayakawa ,  Masao Ito ,  Kenichi Ueda

    发明人： Noboru Tamura ,  Yoshihiro Hayakawa ,  Masao Ito ,  Kenichi Ueda

    IPC分类号： G06F17/30

    CPC分类号： G06F17/30985

    摘要： A data processing apparatus for processing data structured as records, each record including a number of fields. The processing consists of replacing the contents of specific fields in specific records. The apparatus has a memory for storing a record to be processed, a memory for storing data to be used in replacement processing, a register for storing information designating specific record fields to be processed, and a control section for successively reading out the stored record fields. As each field is read out, either the field data or the replacement data are transferred as output data from the apparatus, in accordance with the corresponding information in the aforementioned register.

    摘要翻译： 一种数据处理装置，用于处理构成记录的数据，每个记录包括多个字段。 处理包括在特定记录中替换特定字段的内容。 该装置具有用于存储要处理的记录的存储器，用于存储要用于替换处理的数据的存储器，用于存储指定要处理的特定记录字段的信息的寄存器，以及用于连续读出存储的记录字段的控制部分 。 当每个字段被读出时，根据上述寄存器中的对应信息，现场数据或替换数据作为输出数据从装置传送。

    Phosphoramidite compounds and process for production thereof
    10.
    发明授权
    Phosphoramidite compounds and process for production thereof 失效
    亚磷酰胺化合物及其生产方法

    公开(公告)号：US5026838A

    公开(公告)日：1991-06-25

    申请号：US229773

    申请日：1988-08-04

    申请人： Ryuji Nojiri ,  Yoshihiro Hayakawa ,  Mamoru Uchiyama ,  Hisatoyo Kato ,  Yasuyoshi Chino ,  Shinichiro Tahara

    发明人： Ryuji Nojiri ,  Yoshihiro Hayakawa ,  Mamoru Uchiyama ,  Hisatoyo Kato ,  Yasuyoshi Chino ,  Shinichiro Tahara

    IPC分类号： C07H19/06 ,  C07H19/16 ,  C07H21/00

    CPC分类号： C07H19/06 ,  C07H19/16 ,  C07H21/00 ,  Y02P20/55

    摘要： Phosphoramidite compounds of the general formula ##STR1## wherein each of R.sub.1 and R.sub.2 represents a hydroxyl group having a protective group, or the group --OR.sub.4, R.sub.3 represents a hydrogen atom, a hydroxyl group having a protective group, or the group --OR.sub.4, R.sub.4 represents the group ##STR2## X represents a secondary amino group, R.sub.5 represents an allylic residue or a protective group capable of being split off by beta-cleavage, and B.sup.AOC represents a nucleoside base residue in which the amino or imino group is protected with an allyloxycarbonyl-type residue, with the proviso that only one of R.sub.1, R.sub.2 and R.sub.3 represents the group--OR.sub.4. The compounds can be produced by reacting a nucleoside represented by the general formula ##STR3## wherein each of R.sub.1 ' and R.sub.2 ' represents a hydroxyl group which may have a protective group, R.sub.3 ' represents a hydrogen atom, or a hydroxyl group which may have a protective group, and B.sup.AOC is as defined, with the proviso that only one of R.sub.1 ', R.sub.2 'and R.sub.3 ' is a hydroxyl group,with a phosphoramide compound represented by the general formula ##STR4## wherein X and R.sub.5 are as defined, and Y represents a secondary amino group or a halogen atom.

    摘要翻译： 具有通式 [I]的亚磷酰胺化合物，其中R1和R2各自表示具有保护基的羟基，或-OR4，R3表示氢原子，具有保护基的羟基或基团 -OR4，R4表示基团X表示仲氨基，R5表示能够被β-断裂分解的烯丙基残基或保护基，BAOC表示其中氨基或亚氨基的核苷碱基残基 用烯丙氧基羰基型残基保护，条件是R1，R2和R3中只有一个代表基团-OR4。 化合物可以通过使由通式“IMAGE”表示的核苷反应来制备，其中R 1'和R 2'各自表示可以具有保护基的羟基，R 3'表示氢原子或可具有的羟基 保护基团和BAOC如所定义，条件是R 1'，R 2'和R 3'中仅有一个是羟基，具有由通式“IMAGE”表示的磷酰胺化合物，其中X和R 5如所定义， Y表示仲氨基或卤素原子。