公开(公告)号：US20040099998A1

公开(公告)日：2004-05-27

申请号：US10638338

申请日：2003-08-12

申请人： PENTAX Corporation

发明人： Tsuyoshi Ishikawa ,  Kazuyoshi Yamaguchi ,  Asako Matsushima

IPC分类号： C04B033/32 ,  C04B033/36 ,  C04B035/64

CPC分类号： C04B35/447 ,  C04B35/64 ,  C04B2235/3208 ,  C04B2235/3212 ,  C04B2235/44 ,  C04B2235/447 ,  C04B2235/5436 ,  C04B2235/604 ,  C04B2235/6585 ,  C04B2235/661 ,  C04B2235/77 ,  C04B2235/80 ,  C04B2235/963 ,  C04B2235/9653 ,  C12N5/0068 ,  C12N2533/18

摘要： A method for manufacturing a sintered compact having high density, and a sintered compact manufactured by the manufacturing method are provided. The manufacturing method comprises the steps of preparing hydroxyapatite powder, molding a green compact, shaping the green compact, and sintering the green compact. Further, a method for manufacturing a sintered compact having high light permeability, and a sintered compact manufactured by the manufacturing method are provided. The manufacturing method comprises the steps of preparing hydroxyapatite powder, molding a green compact, shaping the green compact, primary sintering, and secondary sintering. Furthermore, a cell culture base formed from the sintered compact described above is provided, by which affinity of various cells with bone can be properly determined. Moreover, a cell culture base by which affinity of various cells with bone can be properly determined is provided. The cell culture base is mainly composed of a calcium phosphate based compound, and is highly compacted.

摘要翻译： 提供了一种制造具有高密度的烧结体的方法和通过该制造方法制造的烧结体。 制造方法包括制备羟基磷灰石粉末，成型生坯，成形生坯，烧结生坯的步骤。 此外，提供了一种制造具有高透光性的烧结体的方法和通过该制造方法制造的烧结体。 该制造方法包括以下步骤：制备羟基磷灰石粉末，成型生坯，成型生坯，一次烧结和二次烧结。 此外，提供由上述烧结体形成的细胞培养基，可以适当地确定各种细胞与骨的亲和力。 另外，提供了可以适当确定各种细胞与骨的亲和力的细胞培养基。 细胞培养基主要由磷酸钙基化合物组成，高度压实。

公开(公告)号：US20030214062A1

公开(公告)日：2003-11-20

申请号：US10339302

申请日：2003-01-10

申请人： PENTAX Corporation

发明人： Tsuyoshi Ishikawa ,  Masanori Nakasu ,  Takatoshi Kudou ,  Yoshiyuki Ogawara ,  Tsutomu Takahashi ,  Katsumi Kawamura

IPC分类号： B29B009/00

CPC分类号： B01J20/048 ,  A61K6/0235 ,  A61K6/024 ,  A61K6/025 ,  A61K6/033 ,  A61K6/0643 ,  B01J20/282 ,  B01J20/30 ,  B01J20/3028 ,  C01B25/32

摘要： A method of manufacturing a powder, by which it is possible to adjust the strength of the obtained powder is provided. The manufacturing method of a powder involves a step of preparing a slurry containing agglomerated particles of a synthetic material which is produced by reacting a first material and a second material under agitation, and a step of drying the slurry to obtain a powder of the synthetic material. The method has a feature that the particle size of the agglomerated particles is adjusted by, in the step of preparing a slurry, controlling agitation power for agitating the slurry. In the step of preparing a slurry, it is preferable that the slurry is initially agitated at a first agitation power, and at the time when the viscosity of the slurry approaches its maximum value, or at the time when the pH value of the slurry reaches the vicinity of the isoelectric point of the synthetic material, the agitation power is lowered from the first agitation power to a second agitation power. Further, it is preferable that before or after the completion of the reaction of the first material and the second material, the agitation power is increased from the second agitation power to a third agitation power.

摘要翻译： 提供了制造可以调节所得粉末的强度的粉末的方法。 粉末的制造方法包括制备含有通过在搅拌下使第一材料和第二材料反应而制造的合成材料的附聚颗粒的浆料的步骤，以及干燥浆料以获得合成材料的粉末的步骤 。 该方法的特征在于，在制备浆料的步骤中，通过控制用于搅拌浆料的搅拌力来调节凝聚颗粒的粒度。 在制备浆料的步骤中，优选以第一搅拌动力最初搅拌浆料，并且当浆料的粘度接近其最大值时，或者当浆料的pH值达到时 合成材料的等电点附近，搅拌动力从第一搅拌动力降低到第二搅拌动力。 此外，优选的是，在第一材料和第二材料的反应完成之前或之后，搅拌功率从第二搅拌动力增加到第三搅拌动力。

公开(公告)号：US20030176268A1

公开(公告)日：2003-09-18

申请号：US10290160

申请日：2002-11-08

申请人： PENTAX CORPORATION

发明人： Tsuyoshi Ishikawa

IPC分类号： C04B035/01 ,  C04B035/22 ,  C04B035/447

CPC分类号： C04B35/62655 ,  A61K6/0044 ,  A61K6/033 ,  A61K6/0643 ,  A61L27/12 ,  C04B33/14 ,  C04B33/30 ,  C04B33/32 ,  C04B35/447 ,  C04B35/6365 ,  C04B2235/3212 ,  C04B2235/5436 ,  C04B2235/6585 ,  C04B2235/77 ,  C04B2235/96 ,  C04B2235/9653

摘要： The method for manufacturing a sintered piece comprises preparing a molded piece of a composite including calcium phosphate compound such as hydroxyapatite, and baking the molded piece in an oxygen atmosphere to obtain the sintered piece. The oxygen concentration of the oxygen atmosphere is controlled to be not less than 25 vol %, and the relative humidity of the oxygen atmosphere is controlled to be below 30%RH. The baking is performed for 30 minutes to 8 hours at a temperature not less than 1000null C. and below a temperature at which thermal decomposition of the calcium phosphate occurs.

摘要翻译： 制造烧结体的方法包括制备包括磷酸钙化合物如羟基磷灰石的复合材料的模制件，并在氧气氛中烘烤该模制件以获得烧结块。 将氧气氛的氧浓度控制在25体积％以上，将氧气氛的相对湿度控制在30％RH以下。 在不低于1000℃的温度下并在低于发生磷酸钙热分解的温度下进行烘烤30分钟至8小时。