公开(公告)号：US20240002127A1

公开(公告)日：2024-01-04

申请号：US17920569

申请日：2021-04-16

Applicant: Pfizer Inc. ,  BioNTech SE

Inventor： Marjoh Nauta ,  Dirk Jozef Peeters ,  Tom Frank Steven Van Doorslaer ,  Advait Vijay Badkar ,  Ramin Darvari ,  Nicholas William Warne ,  James Jean ,  Danny Pierre G. Hendrikse ,  Ugur Sahin ,  Alptekin Güler ,  Andreas Kuhn ,  Alexander Muik ,  Annette Vogel ,  Kerstin Walzer ,  Sonja Witzel ,  Stephanie Hein ,  Özlem Türeci

IPC: B65D81/127 ,  A61K39/215 ,  B65D77/04 ,  B65D81/38

CPC classification number: B65D81/127 ,  A61K39/215 ,  A61K2039/55555 ,  B65D81/3813 ,  B65D77/0413

Abstract: The present disclosure relates to the fields of packaging, transportation, and storage of temperature-sensitive materials, such as biological and/or pharmaceutical products. Various aspects of such packaging, transportation, and storage are provided herein for ultra-low temperature materials useful for the treatment and/or prevention of disease. The present disclosure also provides packaging materials, methods of transportation, and methods of storage for maintaining biological and/or pharmaceutical materials at ultra-low temperatures in order to maintain the integrity of the materials. The present disclosure further relates to the field of RNA to prevent or treat coronavirus infection.

公开(公告)号：US20220362372A1

公开(公告)日：2022-11-17

申请号：US17733566

申请日：2022-04-29

Applicant: PFIZER INC.

Inventor： Philip Ralph Dormitzer ,  Advait Vijay Badkar ,  Christina Van Geen Hoven ,  Kathrin Ute Jansen ,  Pirada Suphaphiphat Allen ,  Ramin Darvari ,  Mark Duda

IPC: A61K39/145 ,  A61P31/16

Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines comprising polynucleotide molecules encoding one or more influenza antigens, such as hemagglutinin antigens.

公开(公告)号：US20240252612A1

公开(公告)日：2024-08-01

申请号：US18533167

申请日：2023-12-07

Applicant: PFIZER INC.

Inventor： Fanyu Meng ,  Lynn Marie Phelan ,  Pirada Suphaphiphat Allen ,  Nicholas Luksha ,  Bakul Subodh Bhatnagar ,  Ramin Darvari ,  Jayesh Vijay Sonje ,  Serguei Tchessalov ,  Advait Vijay Badkar ,  Michael David Bruchsaler ,  Wouter Joris Knapen ,  Parag Kolhe ,  Marjoh Anne Nauta ,  Naomi Sasha Ramesar ,  Vincent Jurgen L. Van Deyck ,  Bert Van Meervenne ,  Thijs Vanslembrouck ,  Sarah Elizabeth Weiser

IPC: A61K39/145 ,  A61K9/00 ,  A61K9/14 ,  A61K9/19 ,  A61K39/00 ,  A61K47/26

CPC classification number: A61K39/145 ,  A61K9/0019 ,  A61K9/146 ,  A61K9/19 ,  A61K47/26 ,  A61K2039/55555 ,  A61K2039/575

Abstract: The present disclosure relates to compositions comprising RNA molecules encoding an antigen derived from influenza, wherein the RNA may be formulated in a lipid nanoparticle (LNP), and wherein the composition further includes a polypeptide antigen derived from respiratory syncytial virus (RSV) and/or RNA molecules encoding an antigen derived from RSV, wherein the RSV RNA may be may be formulated in an LNP. The present disclosure further relates to the use of the RNA molecules, RNA-LNPs and compositions for the prevention of influenza and RSV infection-induced illness.