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公开(公告)号:US10194939B2
公开(公告)日:2019-02-05
申请号:US14941007
申请日:2015-11-13
Inventor: Masaru Minamiguchi , Yasuaki Okumura , Tatsurou Kawamura , Takahiro Aoki , Masahiko Shioi
IPC: A61B5/00 , A61B17/34 , A61B5/1459 , G01N21/65 , G01N21/64 , A61B5/1455 , A61B5/145
Abstract: A sensor embedding device according to the present disclosure is a sensor embedding device which embeds a sensor in a subject, the sensor having a sensing region in which to detect a state of the subject, including: a needle to be inserted in the subject, the needle having a hole; a sensor retainer to retain the sensor so that the sensor is ready to be embedded inside the subject in such a manner that the sensing region is oriented in a predetermined direction; and a movable section to move the sensor into the subject with a slide of the sensor retainer inside the hole.
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公开(公告)号:US12099062B2
公开(公告)日:2024-09-24
申请号:US16840493
申请日:2020-04-06
Inventor: Masahiko Shioi , Osamu Akasaka , Noriaki Fukumoto
IPC: G01N1/02 , G01N33/00 , G01N33/50 , G01N33/543 , G01N33/569 , G01N33/58 , G01N1/22
CPC classification number: G01N33/582 , G01N33/0075 , G01N33/5091 , G01N33/54373 , G01N33/56983 , G01N1/2273
Abstract: A pathogen detection system includes pathogen detectors disposed in different locations, and a controller. The pathogen detectors include a first pathogen detector and a second pathogen detector. The first pathogen detector transmits a first detection result obtained as a result of pathogen detection to the controller, and the second pathogen detector transmits a second detection result obtained as a result of pathogen detection to the controller. In a case where the first detection result satisfies a predetermined condition, the controller causes the second pathogen detector to change a mode related to the pathogen detection from a first mode to a second mode.
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公开(公告)号:US11768155B2
公开(公告)日:2023-09-26
申请号:US16747021
申请日:2020-01-20
Inventor: Hiroto Yanagawa , Masahiko Shioi , Kazuaki Nishio , Emina Ikeuchi
IPC: G01N21/64 , G01N33/543 , G01N33/68
CPC classification number: G01N21/648 , G01N33/54373 , G01N33/6857 , G01N2021/6441
Abstract: The present disclosure provides a detection device capable of detecting a low concentration of an analyte with high sensitivity. The detection apparatus according to the present disclosure comprises a metal microstructure on which a first VHH antibody having a property of binding specifically to the analyte is immobilized and which generate surface plasmon by being irradiated with excitation light, an inlet through which a second VHH antibody and a sample that may contain an analyte are introduced, wherein the second VHH antibody has a property of binding specifically to the analyte and is labeled with a fluorescent substance, a light source for irradiating the metal microstructure to which the second VHH antibody and the sample have been introduced with the excitation light, and a detection unit for detecting the analyte on the basis of fluorescence generated from the fluorescent substance by the irradiation of the excitation light.
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公开(公告)号:US09861303B2
公开(公告)日:2018-01-09
申请号:US14631095
申请日:2015-02-25
Inventor: Tatsurou Kawamura , Yasuaki Okumura , Masaru Minamiguchi , Masahiko Shioi
IPC: A61B5/1455 , A61B5/145 , G01N21/64 , G01N21/65
CPC classification number: A61B5/14532 , A61B5/1451 , A61B5/1455 , G01N21/64 , G01N21/658
Abstract: An exemplary apparatus for measuring the concentration of a test substance in an organism disclosed herein includes: a measurement system which measures first and second concentrations that are concentrations of the test substance at positions A and B, respectively, where the positions A and B are located inside of the organism but outside of the blood vessel of the organism, and the position B is located more distant from the blood vessel than the position A is; and a decision circuit which determines, based on the first and second concentrations, whether or not an equilibrium has been established yet between a concentration of the test substance inside of the blood vessel and a concentration of the test substance measured at a position inside of the organism but outside of the blood vessel of the organism.
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