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公开(公告)号:US20100016581A1
公开(公告)日:2010-01-21
申请号:US12369104
申请日:2009-02-11
申请人: Paolo Andreella , Giuseppe Barreca , Francesco Tasinato , Massimo Verzini , Marco Demo , Fabio Bassan , Vincenzo Cannata , Giorgio Soriato , Roberto Brescello , Pietro Allegrini , Livius Cotarca
发明人: Paolo Andreella , Giuseppe Barreca , Francesco Tasinato , Massimo Verzini , Marco Demo , Fabio Bassan , Vincenzo Cannata , Giorgio Soriato , Roberto Brescello , Pietro Allegrini , Livius Cotarca
IPC分类号: C07D403/12
CPC分类号: C07D209/12
摘要: The present invention relates to methods of preparing polymorphic Form A of bazedoxifene acetate and polymorphic Form A prepared by such methods.
摘要翻译: 本发明涉及通过这些方法制备的巴西多昔芬乙酸酯多晶型A和多晶型A的方法。
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公开(公告)号:US20130018184A1
公开(公告)日:2013-01-17
申请号:US13453574
申请日:2012-04-23
申请人: Paolo Andreella , Giuseppe Barreca , Francesco Tasinato , Massimo Verzini , Marco Demo , Fabio Bassan , Vincenzo Cannata , Giorgio Soriato , Roberto Brescello , Pietro Allegrini , Livius Cotarca
发明人: Paolo Andreella , Giuseppe Barreca , Francesco Tasinato , Massimo Verzini , Marco Demo , Fabio Bassan , Vincenzo Cannata , Giorgio Soriato , Roberto Brescello , Pietro Allegrini , Livius Cotarca
IPC分类号: C07D403/12
CPC分类号: C07D209/12
摘要: The present invention relates to methods of preparing polymorphic Form A of bazedoxifene acetate and polymorphic Form A prepared by such methods.
摘要翻译: 本发明涉及通过这些方法制备的巴西多昔芬乙酸酯多晶型A和多晶型A的方法。
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公开(公告)号:US08618284B2
公开(公告)日:2013-12-31
申请号:US13453574
申请日:2012-04-23
申请人: Paolo Andreella , Giuseppe Barreca , Francesco Tasinato , Massimo Verzini , Marco Demo , Fabio Bassan , Vincenzo Cannata , Giorgio Soriato , Roberto Brescello , Pietro Allegrini , Livius Cotarca
发明人: Paolo Andreella , Giuseppe Barreca , Francesco Tasinato , Massimo Verzini , Marco Demo , Fabio Bassan , Vincenzo Cannata , Giorgio Soriato , Roberto Brescello , Pietro Allegrini , Livius Cotarca
IPC分类号: A61P19/10 , A61K31/404 , C07D403/10
CPC分类号: C07D209/12
摘要: The present invention relates to methods of preparing polymorphic Form A of bazedoxifene acetate and polymorphic Form A prepared by such methods.
摘要翻译: 本发明涉及通过这些方法制备的巴西多昔芬乙酸酯多晶型物A和多晶型A的方法。
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公开(公告)号:US08183367B2
公开(公告)日:2012-05-22
申请号:US12369104
申请日:2009-02-11
申请人: Paolo Andreella , Giuseppe Barreca , Francesco Tasinato , Massimo Verzini , Marco Demo , Fabio Bassan , Vincenzo Cannata , Giorgio Soriato , Roberto Brescello , Pietro Allegrini , Livius Cotarca
发明人: Paolo Andreella , Giuseppe Barreca , Francesco Tasinato , Massimo Verzini , Marco Demo , Fabio Bassan , Vincenzo Cannata , Giorgio Soriato , Roberto Brescello , Pietro Allegrini , Livius Cotarca
IPC分类号: C07D403/10
CPC分类号: C07D209/12
摘要: The present invention relates to methods of preparing polymorphic Form A of bazedoxifene acetate and polymorphic Form A prepared by such methods.
摘要翻译: 本发明涉及通过这些方法制备的巴西多昔芬乙酸酯多晶型物A和多晶型A的方法。
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公开(公告)号:US20050250762A1
公开(公告)日:2005-11-10
申请号:US11100998
申请日:2005-04-06
申请人: Kadum Ali , Pietro Allegrini , Aldo Belli , Roberto Brescello , Vincenzo Cannata , Malama Chibwe , Livius Cotarca , Shridhar Gangolli , Carl Longfellow , Giorgio Soriato , Massimo Verzini
发明人: Kadum Ali , Pietro Allegrini , Aldo Belli , Roberto Brescello , Vincenzo Cannata , Malama Chibwe , Livius Cotarca , Shridhar Gangolli , Carl Longfellow , Giorgio Soriato , Massimo Verzini
IPC分类号: C07D209/12 , A61K31/55 , C07D43/02
CPC分类号: C07D209/12
摘要: The present invention is directed to a crystalline polymorph of bazedoxifene acetate, compositions containing the same, preparations thereof, and uses thereof.
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公开(公告)号:US07683052B2
公开(公告)日:2010-03-23
申请号:US11100998
申请日:2005-04-06
申请人: Kadum A. Ali , Pietro Allegrini , Aldo Belli , Roberto Brescello , Vincenzo Cannata , Malama K. Chibwe , Livius Cotarca , Shridhar G. Gangolli , Carl E. Longfellow , Giorgio Soriato , Massimo Verzini
发明人: Kadum A. Ali , Pietro Allegrini , Aldo Belli , Roberto Brescello , Vincenzo Cannata , Malama K. Chibwe , Livius Cotarca , Shridhar G. Gangolli , Carl E. Longfellow , Giorgio Soriato , Massimo Verzini
IPC分类号: A61P5/30 , A61K31/55 , C07D403/02
CPC分类号: C07D209/12
摘要: The present invention is directed to a crystalline polymorph of bazedoxifene acetate, compositions containing the same, preparations thereof, and uses thereof.
摘要翻译: 本发明涉及乙酸巴多昔芬的结晶多晶型物,含有它们的组合物,其制备方法及其应用。
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公开(公告)号:US20060155147A1
公开(公告)日:2006-07-13
申请号:US11329503
申请日:2006-01-11
IPC分类号: C07C213/02
CPC分类号: C07D295/088 , C07C213/02
摘要: The present invention provides processes and intermediates for the preparation of aminoethoxybenzyl alcohols of Formula I useful in the production of pharmaceutically useful compounds.
摘要翻译: 本发明提供用于制备可用于制备药用有用化合物的式I的氨基乙氧基苄醇的方法和中间体。
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公开(公告)号:US07375251B2
公开(公告)日:2008-05-20
申请号:US11329503
申请日:2006-01-11
IPC分类号: C07C211/00
CPC分类号: C07D295/088 , C07C213/02
摘要: The present invention provides processes and intermediates for the preparation of aminoethoxybenzyl alcohols of Formula I useful in the production of pharmaceutically useful compounds
摘要翻译: 本发明提供用于制备可用于制备药用有用化合物的式I的氨基乙氧基苄醇的方法和中间体
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公开(公告)号:US07692027B2
公开(公告)日:2010-04-06
申请号:US11415429
申请日:2006-05-02
IPC分类号: C07D403/04
CPC分类号: C07D235/20
摘要: A process for the preparation of telmisartan (I) and novel intermediates useful for its synthesis.
摘要翻译: 一种制备替米沙坦(I)的方法和用于其合成的新型中间体。
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10.
公开(公告)号:US20050282860A1
公开(公告)日:2005-12-22
申请号:US11145927
申请日:2005-06-07
IPC分类号: A61K31/137 , A61K31/445 , C07D211/22 , C07D211/34
CPC分类号: C07D211/22
摘要: The invention provides novel crystalline forms of fexofenadine hydrochloride, a process for the preparation of the novel forms and of the known form A, and their use in therapy.
摘要翻译: 本发明提供盐酸非索非那定的新型结晶形式,一种制备新型和已知形式A的方法及其在治疗中的应用。
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