-
公开(公告)号：US20180016225A1
公开(公告)日：2018-01-18
申请号：US15595267
申请日：2017-05-15
IPC分类号： C07C237/26 , A61K45/06 , A61K31/65
CPC分类号： C07C237/26 , A61K31/65 , A61K45/06 , Y02A50/411
摘要： Methods and compounds for treating diseases with tetracycline compounds having a target therapeutic activity are described.
-
公开(公告)号：US09365500B2
公开(公告)日：2016-06-14
申请号：US14318031
申请日：2014-06-27
发明人： Mark L. Nelson , Roger Frechette , Mohamed Y. Ismail , Laura Honeyman , Todd Bowser , Beena Bhatia
IPC分类号： C07C237/26 , C07D317/66
CPC分类号： C07C237/26 , C07D317/66
摘要： The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and minocycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
-
公开(公告)号：US09278911B2
公开(公告)日：2016-03-08
申请号：US14176923
申请日：2014-02-10
发明人： Mark L. Nelson , Kwasi Ohemeng
IPC分类号： A61K31/65 , C07C237/26 , C07C235/70 , C07C251/48 , C07C255/41 , C07C271/22 , C07C271/54 , C07C271/58 , C07C275/42 , C07C275/54 , C07C279/18 , C07C311/06 , C07C311/08 , C07C333/08 , C07C335/22 , C07C381/10 , C07D295/155 , C07D295/185 , C07D317/60 , C07F9/24 , C07F9/40
CPC分类号： A61K31/65 , C07C235/70 , C07C237/26 , C07C251/48 , C07C255/41 , C07C271/22 , C07C271/54 , C07C271/58 , C07C275/42 , C07C275/54 , C07C279/18 , C07C311/06 , C07C311/08 , C07C333/08 , C07C335/22 , C07C381/10 , C07C2601/08 , C07C2601/10 , C07C2601/16 , C07C2603/46 , C07D295/155 , C07D295/185 , C07D317/60 , C07F9/2475 , C07F9/4006
摘要： The present invention pertains, at least in part, to novel substituted 4-dedimethylamino tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
-
公开(公告)号：US20150321997A1
公开(公告)日：2015-11-12
申请号：US14790179
申请日：2015-07-02
IPC分类号： C07C237/26
CPC分类号： C07C237/26 , A61K31/65
摘要： A method for modulating RNA with tetracycline compounds is described.
摘要翻译： 描述了用四环素化合物调节RNA的方法。
-
公开(公告)号：US20150141381A1
公开(公告)日：2015-05-21
申请号：US14285105
申请日：2014-05-22
IPC分类号： C07C237/26 , A61K45/06 , A61K31/65
CPC分类号： C07C237/26 , A61K31/65 , A61K45/06 , Y02A50/411
摘要： Methods and compounds for treating diseases with tetracycline compounds having a target therapeutic activity are described.
摘要翻译： 描述了用具有目标治疗活性的四环素化合物治疗疾病的方法和化合物。
-
公开(公告)号：US20150045329A1
公开(公告)日：2015-02-12
申请号：US14281357
申请日：2014-05-19
发明人： Mark L. Nelson , Kwasi Ohemeng , Paul Abato , Victor Amoo , Haregewein Assefa , Joel Berniac , Beena Bhatia , Todd Bowser , Jackson Chen , Mark Grier , Laura Honeyman , Mohamed Y. Ismail , Oak K. Kim , Jude Mathews , Rachid Mechiche
IPC分类号： C07C237/48
CPC分类号： C07C237/48 , A61K31/65 , C07C237/26 , C07C271/22 , C07C271/54 , C07C275/28 , C07C275/30 , C07C2601/02 , C07C2601/14 , C07C2601/16 , C07C2603/46
摘要： The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
摘要翻译： 本发明至少部分地涉及新的取代的四环素化合物。 这些四环素化合物可用于治疗许多四环素化合物反应状态，例如细菌感染和肿瘤，以及四环素化合物的其它已知应用，例如阻断四环素外排和调节基因表达。
-
公开(公告)号：US20140309199A1
公开(公告)日：2014-10-16
申请号：US14318031
申请日：2014-06-27
发明人： Mark L. Nelson , Roger Frechette , Mohamed Y. Ismail , Laura Honeyman , Todd Bowser , Beena Bhatia
IPC分类号： C07C237/26
CPC分类号： C07C237/26 , C07D317/66
摘要： The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and minocycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
摘要翻译： 本发明至少部分地涉及新的9-取代的米诺环素化合物。 这些米诺环素化合物可用于治疗许多四环素化合物反应状态，例如细菌感染和肿瘤，以及其他已知的米诺环素和米诺环素化合物的一般应用，例如阻断四环素外排和调节基因表达。
-
公开(公告)号：US20190040001A1
公开(公告)日：2019-02-07
申请号：US15899535
申请日：2018-02-20
IPC分类号： C07C237/26 , A61K31/65
摘要： A method for modulating RNA with tetracycline compounds is described.
-
公开(公告)号：US09562003B2
公开(公告)日：2017-02-07
申请号：US14790179
申请日：2015-07-02
IPC分类号： C07C237/26 , A61K31/65
CPC分类号： C07C237/26 , A61K31/65
摘要： A method for modulating RNA with tetracycline compounds is described.
摘要翻译： 描述了用四环素化合物调节RNA的方法。
-
公开(公告)号：US20170305840A1
公开(公告)日：2017-10-26
申请号：US15374329
申请日：2016-12-09
发明人： Mark L. Nelson , Kwasi Ohemeng , Paul Abato , Victor Amoo , Haregewein Assefa , Joel Berniac , Beena Bhatia , Todd Bowser , Jackson Chen , Mark Grier , Laura Honeyman , Mohamed Y. Ismail , Oak K. Kim , Jude Mathews , Rachid Mechiche
IPC分类号： C07C237/48 , C07C275/28 , C07C271/54 , C07C271/22 , C07C275/30 , C07C237/26 , C07C2603/46 , A61K31/65 , C07C2601/14 , C07C2601/16 , C07C2601/02
CPC分类号： C07C237/48 , A61K31/65 , C07C237/26 , C07C271/22 , C07C271/54 , C07C275/28 , C07C275/30 , C07C2601/02 , C07C2601/14 , C07C2601/16 , C07C2603/46 , Y02A50/411 , Y02A50/473
摘要： The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
-
-
-
-
-
-
-
-
-
搜索结果
14 条记录 (耗时 0.037 秒)
