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公开(公告)号：US20070276046A1
公开(公告)日：2007-11-29
申请号：US10569403
申请日：2004-04-22
IPC分类号： A61K31/165 , A61K31/44 , A61K31/381 , A61K31/34
CPC分类号： A61K31/381 , A61K31/165
摘要： Methods of using certain a-aminoamide derivatives as anti-inflammatory agents. The anti-inflammatory agents of the invention are able to reduce or even stop inflammatory s conditions substantially without side effects.
摘要翻译： 使用某些α-氨基酰胺衍生物作为抗炎剂的方法。 本发明的抗炎剂能够基本上没有副作用减少甚至阻止炎性病症。
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公开(公告)号：US20100016440A1
公开(公告)日：2010-01-21
申请号：US12544456
申请日：2009-08-20
IPC分类号： A61K31/165 , A61P29/00
CPC分类号： A61K31/381 , A61K31/165
摘要： Methods of using certain a-aminoamide derivatives as anti-inflammatory agents. The anti-inflammatory agents of the invention are able to reduce or even stop inflammatory s conditions substantially without side effects.
摘要翻译： 使用某些α-氨基酰胺衍生物作为抗炎剂的方法。 本发明的抗炎剂能够基本上没有副作用减少甚至阻止炎性病症。
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3.发明授权Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders 有权用于治疗下尿路疾病的α-氨基酰胺衍生物公开(公告)号：US07718815B2
公开(公告)日：2010-05-18
申请号：US10586494
申请日：2005-01-20
申请人： Elena Barbanti , Orietta Veneroni , Florian Thaler , Roberto Pellicciari , Luca Benatti , Patricia Salvati
发明人： Elena Barbanti , Orietta Veneroni , Florian Thaler , Roberto Pellicciari , Luca Benatti , Patricia Salvati
IPC分类号： C07D307/87 , C07D307/00
CPC分类号： A61K31/4015 , A61K31/165 , A61K31/277 , A61K31/34 , A61K31/353 , A61K31/381 , C07D307/28 , C07D311/58 , C07D313/08 , C07D333/32 , C07D333/58
摘要： Methods of using certain α-aminoamide derivatives to treat lower urinary tract disorders. The therapeutic agents of the invention are able to reduce or even stop the lower urinary tract disorders substantially without side effects.
摘要翻译： 使用某些α-氨基酰胺衍生物治疗下尿路疾病的方法。 本发明的治疗剂能够基本上没有副作用减少甚至阻止下尿路疾病。
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4.发明申请Alpha-Aminoamide Derivatives Useful in the Treatment of Lower Urinary Tract Disorders 有权用于治疗下尿路障碍的α-氨基酰胺衍生物公开(公告)号：US20080132567A1
公开(公告)日：2008-06-05
申请号：US10586494
申请日：2005-01-20
申请人： Elena Barbanti , Orietta Veneroni , Florian Thaler , Roberto Pellicciari , Luca Benatti , Patricia Salvati
发明人： Elena Barbanti , Orietta Veneroni , Florian Thaler , Roberto Pellicciari , Luca Benatti , Patricia Salvati
IPC分类号： A61K31/165 , A61K31/343 , A61P13/02 , C07D307/77
CPC分类号： A61K31/4015 , A61K31/165 , A61K31/277 , A61K31/34 , A61K31/353 , A61K31/381 , C07D307/28 , C07D311/58 , C07D313/08 , C07D333/32 , C07D333/58
摘要： Methods of using certain α-aminoamide derivatives to treat lower urinary tract disorders. The therapeutic agents of the invention are able to reduce or even stop the lower urinary tract disorders substantially without side effects.
摘要翻译： 使用某些α-氨基酰胺衍生物治疗下尿路疾病的方法。 本发明的治疗剂能够基本上没有副作用减少甚至阻止下尿路疾病。
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5.发明授权Pharmaceutical composition comprising gabapentin or an analogue thereof and an α-aminoamide and its analgesic use 有权包含加巴喷丁或其类似物和α-氨基酰胺及其止痛用途的药物组合物公开(公告)号：US08710040B2
公开(公告)日：2014-04-29
申请号：US13313627
申请日：2011-12-07
IPC分类号： A01N37/12 , A01N37/46 , A61K31/195
CPC分类号： A61K31/16 , A61K31/445 , A61K2300/00
摘要： There is disclosed a pharmaceutical composition comprising gabapentin or an analogue thereof (pregabalin or tiagabine) and an α-aminoamide and its analgesic use. A synergistic effect of the respective analgesic activities without concomitant increase of side effects was observed.
摘要翻译： 公开了包含加巴喷丁或其类似物（普瑞巴林或噻加滨）和α-氨基酰胺及其止痛用途的药物组合物。 观察到相应镇痛活性的协同作用，而不伴随副作用增加。
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6.发明授权Pharmaceutical composition comprising gabapentin or an analogue thereof and an α-aminoamide and its analgesic use 有权包含加巴喷丁或其类似物和α-氨基酰胺及其止痛用途的药物组合物公开(公告)号：US08084447B2
公开(公告)日：2011-12-27
申请号：US10487931
申请日：2002-08-09
IPC分类号： A01N37/12 , A01N37/46 , A61K31/195
CPC分类号： A61K31/16 , A61K31/445 , A61K2300/00
摘要： There is disclosed a pharmaceutical composition comprising gabapentin or an analogue thereof (pregabalin or tiagabine) and an α-aminoamide and its analgesic use. A synergistic effect of the respective analgesic activities without concomitant increase of side effects was observed.
摘要翻译： 公开了包含加巴喷丁或其类似物（普瑞巴林或噻加滨）和α-氨基酰胺及其止痛用途的药物组合物。 观察到相应镇痛活性的协同作用，而不伴随副作用增加。
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公开(公告)号：US20070093495A1
公开(公告)日：2007-04-26
申请号：US10559982
申请日：2004-04-08
IPC分类号： A61K31/498 , A61K31/48 , A61K31/473 , A61K31/137
CPC分类号： A61K31/165 , A61K31/137 , A61K31/16 , A61K31/473 , A61K31/4745 , A61K31/475 , A61K31/48 , A61K31/485 , A61K31/498 , A61K31/4985 , A61K31/55 , A61K45/06 , A61K2300/00
摘要： New uses of safinamide, safinamide derivatives and MAO-B inhibitors in novel types of treatment for Parkinson's Disease are described. More specifically, the invention relates to methods for treating Parkinson's Disease through the administration of safinamide, a safinamide derivative, or a MAO-B inhibitor, in combination with other Parkinson's Disease agents or treatments, such as levodopa/PDI or dopamine agonists.
摘要翻译： 描述了safinamide，safinamide衍生物和MAO-B抑制剂在新型帕金森病治疗类型中的新用途。 更具体地，本发明涉及通过与其他帕金森病药物或治疗如左旋多巴/ PDI或多巴胺激动剂的组合组合施用safinamide，safinamide衍生物或MAO-B抑制剂来治疗帕金森病的方法。
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8.发明授权公开(公告)号：US08445513B2
公开(公告)日：2013-05-21
申请号：US11578988
申请日：2005-04-19
申请人： Claudia Besana , Elena Barbanti , Emanuela Izzo , Florian Thaler , Ruggero Fariello , Patricia Salvati , Luca Benatti
发明人： Claudia Besana , Elena Barbanti , Emanuela Izzo , Florian Thaler , Ruggero Fariello , Patricia Salvati , Luca Benatti
IPC分类号： A61K31/445 , A61K31/40 , A61K31/277 , A61K31/165 , A61K31/137
CPC分类号： A61K31/165 , A61K31/198 , A61K31/381 , A61K31/40 , A61K45/06 , A61K2300/00
摘要： The invention relates to the use of certain alpha-aminoamide derivatives in the treatment of RLS and addictive disorders. The compounds of this invention are able to reduce or even stop the symptoms of RLS and addictive disorders substantially without side effects.
摘要翻译： 本发明涉及某些α-氨基酰胺衍生物在治疗RLS和成瘾性疾病中的应用。 本发明的化合物能够基本上没有副作用减少甚至停止RLS和成瘾性疾病的症状。
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9.发明申请Alpha-Aminoamide Derivatives Useful In The Treatment Of Restless Legs Syndrome And Addictive Disorders 有权用于治疗不宁腿综合征和上瘾性疾病的α-氨基酰胺衍生物公开(公告)号：US20070203182A1
公开(公告)日：2007-08-30
申请号：US11578988
申请日：2005-04-19
申请人： Claudia Besana , Elena Barbanti , Emanuela Izzo , Florian Thaler , Ruggero Fariello , Patricia Salvati , Luca Benatti
发明人： Claudia Besana , Elena Barbanti , Emanuela Izzo , Florian Thaler , Ruggero Fariello , Patricia Salvati , Luca Benatti
IPC分类号： A61K31/445 , A61K31/40 , A61K31/277 , A61K31/165 , A61K31/137
CPC分类号： A61K31/165 , A61K31/198 , A61K31/381 , A61K31/40 , A61K45/06 , A61K2300/00
摘要： The invention relates to the use of certain alpha-aminoamide derivatives in the treatment of RLS and addictive disorders. The compounds of this invention are able to reduce or even stop the symptoms of RLS and addictive disorders substantially without side effects.
摘要翻译： 本发明涉及某些α-氨基酰胺衍生物在治疗RLS和成瘾性疾病中的应用。 本发明的化合物能够基本上没有副作用减少甚至停止RLS和成瘾性疾病的症状。
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公开(公告)号：US08283380B2
公开(公告)日：2012-10-09
申请号：US10559982
申请日：2004-04-08
IPC分类号： A61K31/137 , A61K31/165 , A61K31/192 , A61K31/195 , A61P25/16
CPC分类号： A61K31/165 , A61K31/137 , A61K31/16 , A61K31/473 , A61K31/4745 , A61K31/475 , A61K31/48 , A61K31/485 , A61K31/498 , A61K31/4985 , A61K31/55 , A61K45/06 , A61K2300/00
摘要： New uses of safinamide, safinamide derivatives and MAO-B inhibitors in novel types of treatment for Parkinson's Disease are described. More specifically, the invention relates to methods for treating Parkinson's Disease through the administration of safinamide, a safinamide derivative, or a MAO-B inhibitor, in combination with other Parkinson's Disease agents or treatments, such as levodopa/PDI or dopamine agonists.
摘要翻译： 描述了safinamide，safinamide衍生物和MAO-B抑制剂在新型帕金森病治疗类型中的新用途。 更具体地，本发明涉及通过与其他帕金森病药物或治疗如左旋多巴/ PDI或多巴胺激动剂的组合组合施用safinamide，safinamide衍生物或MAO-B抑制剂来治疗帕金森病的方法。
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