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公开(公告)号：US4743537A
公开(公告)日：1988-05-10
申请号：US942506
申请日：1986-12-24
摘要： A sterility indicator which comprises means defining an elongated outer compartment having liquid impermeable and substantially non-gas absorptive walls, said compartment having a closed end and a first opening at a distal end thereof and a second opening which is gas transmissive and bacteria-impermeable disposed at least partially around the perimeter of said outer compartment and located near said first opening, with a predetermined number of viable microorganisms suitable for monitoring steam sterilization being confined within said outer compartment adjacent said second opening, and a predetermined number of viable microorganisms suitable for monitoring gas sterilization being confined within said outer compartment away from said second opening and opposite said distal end; a closure member normally closing said first opening and movable to a second position to also close said second opening; and an inner compartment containing a nutrient medium disposed within said outer compartment with said nutrient medium being out of direct contact with said microorganisms, said inner compartment being adapted to open in response to external pressure thereby permitting said nutrient medium to contact said microorganisms.
摘要翻译： 一种无菌指示器，其包括限定具有液体不可渗透和基本上非气体吸收壁的细长外隔室的装置，所述隔室具有封闭端和位于其远端的第一开口，以及第二开口，其为气体透过和细菌不渗透处理 至少部分地围绕所述外隔室的周边并且位于所述第一开口附近，具有预定数量的适用于监测蒸汽灭菌的活微生物被限制在邻近所述第二开口的所述外隔室内，以及预定数量的适用于监测的活微生物 气体灭菌被限制在所述外隔室内，远离所述第二开口并与所述远端相对; 关闭构件通常关闭所述第一开口并且可移动到第二位置以也关闭所述第二开口; 以及包含设置在所述外部隔室内的营养培养基的内部隔室，所述营养培养基不与所述微生物直接接触，所述内部隔室适于响应于外部压力而打开，从而允许所述营养培养基接触所述微生物。
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公开(公告)号：US4717661A
公开(公告)日：1988-01-05
申请号：US820354
申请日：1986-01-21
摘要： The present invention is directed to sterility indicators of the self-contained biological type and provides a device that assures direct impingement of the sterilant onto the microproorganisms. In this manner, the sterilant exposure conditions experienced by the test organisms reflects the exposure conditions to which the articles in the sterilizer are subjected. The device of the invention provides that the microorganisms are not directly contiguous with the ampule containing the aqueous nutrient medium.
摘要翻译： 本发明涉及自体生物学类型的无菌指标，并且提供一种确保灭菌剂直接冲击微生物的装置。 以这种方式，测试生物体经历的灭菌剂暴露条件反映了灭菌器中物品经受的暴露条件。 本发明的装置提供了微生物不与含有营养培养基的安瓿直接邻接。
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公开(公告)号：US07666671B2
公开(公告)日：2010-02-23
申请号：US11538905
申请日：2006-10-05
CPC分类号： G01N1/312 , G01N1/30 , G01N2001/305
摘要： A method of fixing a biological sample on a slide for cytological analysis, includes transferring a sample to a slide, applying a material having a slide-fixing amount of an inactivated, fixative to the slide, and activating the fixative. By way of example, the material may comprise a tape impregnated with the inactivated fixative, which tape may be removed from the slide after the fixative is activated.
摘要翻译： 将生物样品固定在用于细胞学分析的载玻片上的方法包括将样品转移到载玻片上，将具有滑动固定量的材料固定在载玻片上，并激活固定剂。 作为示例，材料可以包括浸渍有灭活固定剂的带，该固定剂在固定剂被活化后可以从载玻片中除去。
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公开(公告)号：US09186690B2
公开(公告)日：2015-11-17
申请号：US13018889
申请日：2011-02-01
CPC分类号： B05B11/305 , A61F9/0008 , B05B11/00444 , B05B11/0059 , B05B11/304 , B05B11/3052 , B05B11/307 , B05B11/3094
摘要： A hand-operable system for ejecting a fluid composition into an eye, the system including: (1) a container having a container opening and containing the fluid composition; (2) a double-acting pump mechanism securely disposed over the container opening; and (3) an actuator that is disposed over, and extends radially outward from, the pump mechanism, for actuating the pump mechanism by applying a force thereon, wherein the pump mechanism includes a passage for the fluid composition, and the passage is positively sealed off when the application of the force is discontinued.
摘要翻译： 一种用于将流体组合物喷射到眼睛中的手动操作系统，所述系统包括：（1）容器，其具有容器开口并容纳所述流体组合物; （2）牢固地设置在容器开口上的双作用泵机构; 和（3）致动器，其设置在所述泵机构的上方且径向向外延伸，以通过在其上施加力来致动所述泵机构，其中所述泵机构包括用于所述流体组合物的通道，并且所述通道被正密封 当力的应用停止时关闭。
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公开(公告)号：US20120197219A1
公开(公告)日：2012-08-02
申请号：US13018889
申请日：2011-02-01
IPC分类号： A61F9/00
CPC分类号： B05B11/305 , A61F9/0008 , B05B11/00444 , B05B11/0059 , B05B11/304 , B05B11/3052 , B05B11/307 , B05B11/3094
摘要： A hand-operable system for ejecting a fluid composition into an eye, the system comprises: (1) a container having a container opening and containing the fluid composition; (2) a double-acting pump mechanism securely disposed over the container opening; and (3) an actuator that is disposed over, and extends radially outward from, said pump mechanism, for actuating the pump mechanism by applying a force thereon, wherein said pump mechanism comprises a passage for said fluid composition, and said passage is positively sealed off when the application of said force is discontinued.
摘要翻译： 一种用于将流体组合物喷射到眼睛中的手动操作系统，该系统包括：（1）具有容器开口并容纳流体组合物的容器; （2）牢固地设置在容器开口上的双作用泵机构; 和（3）致动器，其设置在所述泵机构的上方且径向向外延伸，用于通过在其上施加力来致动所述泵机构，其中所述泵机构包括用于所述流体组合物的通道，并且所述通道被正密封 当所述力的应用停止时关闭。
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6.发明授权Disposable sterilization test pack for evaluating steam and ethylene oxide sterilization 失效一次性消毒测试包，用于评估蒸汽和环氧乙烷灭菌
公开(公告)号：US5824553A
公开(公告)日：1998-10-20
申请号：US193712
申请日：1994-02-09
CPC分类号： G01N31/226 , A61L2/206 , A61L2/28 , C12Q1/22
摘要： Structure for evaluating the efficacy of sterilization apparatus using either steam or ethylene oxide as sterilant is disclosed. The structure includes an insert of porous material having a cavity formed therethrough for retaining a biological or chemical indicator. The porous material has homogeneous porosity throughout. The insert of porous material and indicator are enclosed within an outer covering which is relatively impervious to penetration of gases and which provides restricted pathways to air and sterilant. The outer covering is provided with removable portions which are removed when the structure is used to evaluate ethylene oxide sterilization. Removal of the portions enlarges the existing pathways for ingress and egress of gases which may be appropriate in certain efficacy testing.
摘要翻译： 公开了用于评估使用蒸汽或环氧乙烷作为灭菌剂的灭菌装置的功效的结构。 该结构包括具有穿过其形成的空腔的多孔材料的插入物，用于保持生物或化学指示剂。 多孔材料贯穿整个孔隙。 多孔材料和指示剂的插入物封闭在相对不透气体的外覆盖物内，并且向空气和灭菌剂提供限制的途径。 外覆盖层设置有可移除部分，当该结构用于评估环氧乙烷灭菌时，该部分被移除。 这些部分的去除扩大了在某些功效测试中可能适合的气体进入和排出的现有途径。
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