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1.发明授权Use of cyanoacrylate adhesives for providing a protective barrier film for the skin 失效使用氰基丙烯酸酯粘合剂为皮肤提供保护性屏障膜
公开(公告)号：US5580565A
公开(公告)日：1996-12-03
申请号：US299935
申请日：1994-09-01
CPC分类号： A61L26/0014 , A61L31/048
摘要： A cyanoacrylate adhesive is applied onto skin area prone to exposure to discharge by patients suffering from incontinence so as to shield the skin from direct contact with the discharge. The adhesive can also be applied over medicament that has been applied onto skin surface and onto skin along the periphery of a stoma.
摘要翻译： 将氰基丙烯酸酯粘合剂施加到容易遭受失禁患者放电的皮肤区域上，以防止皮肤与排出物直接接触。 粘合剂也可以施加在沿着造口的周边施加到皮肤表面和皮肤上的药物上。
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公开(公告)号：US06191202B1
公开(公告)日：2001-02-20
申请号：US08888322
申请日：1997-07-03
IPC分类号： C08K510
CPC分类号： C08K5/41 , C08F22/32 , C08F222/32 , C09J4/00 , C08L33/14 , C08F222/00
摘要： Alkyl cyanoacrylate compositions comprising at least one alkyl cyanoacrylate, a biocompatible plasticizer (preferably an acyl trialkyl citrate wherein the acyl group contains from 2 to 4 carbon atoms and each alkyl group contains from 4 to 6 carbon atoms), and SO2 as an anionic polymerization inhibitor are provided. These compositions are suitable for topical application to human skin.
摘要翻译： 氰基丙烯酸烷基酯组合物，其包含至少一种氰基丙烯酸烷基酯，生物相容性增塑剂（优选酰基三烷基柠檬酸盐，其中酰基含有2至4个碳原子，每个烷基含有4至6个碳原子）和SO 2作为阴离子聚合抑制剂 被提供。 这些组合物适用于局部应用于人体皮肤。
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3.发明授权公开(公告)号：US06492434B1
公开(公告)日：2002-12-10
申请号：US08393019
申请日：1995-02-27
IPC分类号： C08K608
CPC分类号： A61K31/74 , A61L24/06 , Y10S514/925 , Y10S514/928 , C08L35/04
摘要： A cyanoacrylate adhesive is applied onto intact surface skin areas prone to ulceration so as to inhibit formation of surface skin ulcers.
摘要翻译： 将氰基丙烯酸酯粘合剂施加到易于溃疡的完整表面皮肤区域上，以抑制表面皮肤溃疡的形成。
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公开(公告)号：US5665817A
公开(公告)日：1997-09-09
申请号：US578492
申请日：1995-12-26
IPC分类号： A61L15/16 , A61L24/00 , C08F2/40 , C08F2/44 , C08F22/32 , C08F222/32 , C08K5/41 , C09J4/00 , C09J4/04 , C08K5/09
CPC分类号： C08K5/41 , C08F22/32 , C08F222/32 , C09J4/00
摘要： Alkyl cyanoacrylate compositions comprising at least one alkyl cyanoacrylate, a biocompatible plasticizer (preferably dioctyl phthalate), and SO.sub.2 as an anionic polymerization inhibitor are provided. These compositions are suitable for topical application to human skin.
摘要翻译： 提供包含至少一种氰基丙烯酸烷基酯，生物相容性增塑剂（优选邻苯二甲酸二辛酯）和作为阴离子聚合抑制剂的SO 2的氰基丙烯酸烷基酯组合物。 这些组合物适用于局部应用于人体皮肤。
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5.发明授权Methods for reducing skin irritation from artificial devices by use of cyanoacrylate adhesives 失效使用氰基丙烯酸酯粘合剂减少人造装置皮肤刺激的方法
公开(公告)号：US5653769A
公开(公告)日：1997-08-05
申请号：US542034
申请日：1995-10-12
CPC分类号： A61L26/0014 , A61L15/24 , C09J4/00
摘要： A cyanoacrylate adhesive is applied onto surface skin areas prone to ulceration or irritation so as to inhibit irritation of the surface skin due to contact with an artificial device such as prosthetic devices, bandages, casts, etc.
摘要翻译： 将氰基丙烯酸酯粘合剂施加到容易发生溃疡或刺激的表面皮肤区域上，以便抑制由于与诸如假体装置，绷带，铸件等的人造装置的接触而对表皮的刺激。
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公开(公告)号：US5480935A
公开(公告)日：1996-01-02
申请号：US299993
申请日：1994-09-01
IPC分类号： A61L15/16 , A61L24/00 , C08F2/40 , C08F2/44 , C08F22/32 , C08F222/32 , C08K5/41 , C09J4/00 , C09J4/04 , C08K5/09
CPC分类号： C08K5/41 , C08F22/32 , C08F222/32 , C09J4/00
摘要： Alkyl cyanoacrylate compositions comprising at least one alkyl cyanoacrylate, a biocompatible plasticizer (preferably dioctyl phthalate), and SO.sub.2 as an artionic polymerization inhibitor are provided. These compositions are suitable for topical application to human skin.
摘要翻译： 提供包含至少一种氰基丙烯酸烷基酯，生物相容性增塑剂（优选邻苯二甲酸二辛酯）和作为挥发性阻聚剂的SO 2的氰基丙烯酸烷基酯组合物。 这些组合物适用于局部应用于人体皮肤。
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公开(公告)号：US5716607A
公开(公告)日：1998-02-10
申请号：US643400
申请日：1996-05-06
IPC分类号： A61K47/30 , A61K31/00 , A61K31/74 , A61K31/78 , A61K31/785 , A61L26/00 , A61P17/00 , A61P39/00
CPC分类号： A61K31/785 , A61K31/78 , A61L26/0014
摘要： Disclosed are methods for inhibiting late radiation-induced skin damage during treatment of a patient with ionizing radiation by application of a layer of biocompatible polymer to the skin surface prior to exposure of the surface to ionizing radiation.
摘要翻译： 公开的是在将表面暴露于电离辐射之前通过将生物相容性聚合物层施加到皮肤表面上来抑制患有电离辐射的患者的晚期辐射诱导的皮肤损伤的方法。
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8.发明授权Use of cyanoacrylate adhesive compositions to inhibit acute radiation-induced skin damage 失效使用氰基丙烯酸酯粘合剂组合物抑制急性辐射诱导的皮肤损伤
公开(公告)号：US5554365A
公开(公告)日：1996-09-10
申请号：US435590
申请日：1995-05-05
IPC分类号： A61K47/30 , A61K31/00 , A61K31/74 , A61K31/78 , A61K31/785 , A61L26/00 , A61P17/00 , A61P39/00
CPC分类号： A61K31/785 , A61K31/78 , A61L26/0014
摘要： Disclosed are methods for inhibiting acute and/or late radiation/induced skin damage during treatment of a patient with ionizing radiation by application of a layer of cyanoacrylate adhesive to the skin surface prior to exposure of the surface to ionizing radiation.
摘要翻译： 公开的是在将表面暴露于电离辐射之前，通过将一层氰基丙烯酸酯粘合剂施加到皮肤表面来治疗患有电离辐射的患者期间的急性和/或晚期辐射/诱导的皮肤损伤的方法。
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公开(公告)号：US5716608A
公开(公告)日：1998-02-10
申请号：US643468
申请日：1996-05-06
IPC分类号： A61K47/30 , A61K31/00 , A61K31/74 , A61K31/78 , A61K31/785 , A61L26/00 , A61P17/00 , A61P39/00 , A61K71/78
CPC分类号： A61K31/785 , A61K31/78 , A61L26/0014
摘要： Disclosed are methods for inhibiting acute radiation-induced skin damage during treatment of a patient with ionizing radiation by application of a layer of biocompatible polymer to the skin surface prior to exposure of the surface to ionizing radiation.
摘要翻译： 公开的是在将表面暴露于电离辐射之前通过将生物相容性聚合物层施加到皮肤表面上来治疗患有电离辐射的患者的急性辐射诱导的皮肤损伤的方法。
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10.发明授权
公开(公告)号：US5957877A
公开(公告)日：1999-09-28
申请号：US963370
申请日：1997-11-03
CPC分类号： A61L31/16 , A61L26/0014 , A61L26/0066 , A61L26/0071 , A61L31/048 , A61L31/141 , A61L2300/202 , A61L2300/404
摘要： Disclosed are methods for draping a surgical site prior to surgery. Specifically, the methods of this invention involve the in situ formation of a cyanoacrylate polymeric drape on the skin surface of a patient peripheral to the surgical site. Surgery is then conducted at the surgical site.
摘要翻译： 公开了在手术之前将手术部位悬垂的方法。 具体地说，本发明的方法涉及在外科手术部位外周的患者的皮肤表面上原位形成氰基丙烯酸酯聚合物覆盖物。 然后在手术部位进行手术。
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