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公开(公告)号：US20070066600A1
公开(公告)日：2007-03-22
申请号：US11510324
申请日：2006-08-25
申请人： Patrizia Caldirola , Ulf Bremberg , Gary Johansson , Andrew Mott , Annika Jensen , Katarina Beierlien , Markus Thor , Lars Tedenborg
发明人： Patrizia Caldirola , Ulf Bremberg , Gary Johansson , Andrew Mott , Annika Jensen , Katarina Beierlien , Markus Thor , Lars Tedenborg
IPC分类号： A61K31/551 , A61K31/496 , A61K31/495 , A61K31/4745 , A61K31/445 , A61K31/4709
CPC分类号： C07D295/096 , A61K31/495 , A61K31/4965 , C07D215/38 , C07D215/40 , C07D217/22 , C07D241/04 , C07D243/08 , C07D295/135 , C07D307/78 , C07D307/79 , C07D319/18 , C07D333/34 , C07D409/12 , C07D413/12 , C07D471/04 , C07D487/04 , C07D487/08
摘要： The present invention relates to substituted sulfonamide compounds of the general formula (I), wherein P is sulfonamide or amide-substituted sulfonic acid, which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
摘要翻译： 本发明涉及通式（I）的取代磺酰胺化合物，其中P是磺酰胺或酰胺取代的磺酸，该化合物潜在地用于预防和治疗与肥胖，II型糖尿病和/或 中枢神经系统疾病。
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公开(公告)号：US07572787B2
公开(公告)日：2009-08-11
申请号：US11510324
申请日：2006-08-25
申请人： Patrizia Caldirola , Ulf Bremberg , Gary Johansson , Andrew Mott , Annika Jenmalm Jensen , Katarina Beierlien , Markus Thor , Lars Tedenborg
发明人： Patrizia Caldirola , Ulf Bremberg , Gary Johansson , Andrew Mott , Annika Jenmalm Jensen , Katarina Beierlien , Markus Thor , Lars Tedenborg
IPC分类号： A61P25/00 , A61K31/55 , A61K31/495 , A61K31/50 , A61K31/4965 , A61K31/445 , A61K31/40 , C07D243/08 , C07D241/00 , C07D211/06 , C07D487/00
CPC分类号： C07D295/096 , A61K31/495 , A61K31/4965 , C07D215/38 , C07D215/40 , C07D217/22 , C07D241/04 , C07D243/08 , C07D295/135 , C07D307/78 , C07D307/79 , C07D319/18 , C07D333/34 , C07D409/12 , C07D413/12 , C07D471/04 , C07D487/04 , C07D487/08
摘要： The present invention relates to substituted sulfonamide compounds of the general formula (I), wherein P is sulfonamide or amide-substituted sulfonic acid, which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
摘要翻译： 本发明涉及通式（I）的取代磺酰胺化合物，其中P是磺酰胺或酰胺取代的磺酸，该化合物潜在地用于预防和治疗与肥胖，II型糖尿病和/或 中枢神经系统疾病。
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公开(公告)号：US07144883B2
公开(公告)日：2006-12-05
申请号：US10167141
申请日：2002-06-11
申请人： Patrizia Caldirola , Gary Johansson , Andrew Mott , Katarina Beierlien , Markus Thor , Lars Tedenborg , Ulf Bremberg , Annika Jenmalm Jensen
发明人： Patrizia Caldirola , Gary Johansson , Andrew Mott , Katarina Beierlien , Markus Thor , Lars Tedenborg , Ulf Bremberg , Annika Jenmalm Jensen
IPC分类号： A61P3/04 , A61P7/00 , A61K31/42 , A61K31/445 , A61K31/497
CPC分类号： C07D295/096 , A61K31/495 , A61K31/4965 , C07D215/38 , C07D215/40 , C07D217/22 , C07D241/04 , C07D243/08 , C07D295/135 , C07D307/78 , C07D307/79 , C07D319/18 , C07D333/34 , C07D409/12 , C07D413/12 , C07D471/04 , C07D487/04 , C07D487/08
摘要： The present invention relates to substituted sulfonamide compounds of the general formula (I), wherein P is sulfonamide or amide-substituted sulfonic acid, which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system
摘要翻译： 本发明涉及通式（I）的取代磺酰胺化合物，其中P是磺酰胺或酰胺取代的磺酸，该化合物潜在地用于预防和治疗与肥胖，II型糖尿病和/或 中枢神经系统疾病
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公开(公告)号：US20100222330A1
公开(公告)日：2010-09-02
申请号：US12781355
申请日：2010-05-17
申请人： Patrizia Caldirola , Gary Johansson , Andrew Mott , Katarina Beierlein , Markus Thor , Lars Tedenborg , Ulf Bremberg , Annika Jenmalm Jensen
发明人： Patrizia Caldirola , Gary Johansson , Andrew Mott , Katarina Beierlein , Markus Thor , Lars Tedenborg , Ulf Bremberg , Annika Jenmalm Jensen
IPC分类号： A61K31/551 , C07D295/135 , A61K31/495 , A61P3/10 , A61P3/04 , A61P25/22 , A61P25/24 , A61P25/06 , A61P25/18 , A61P25/28 , A61P25/30 , A61P25/16 , C07D243/08 , C07D471/04 , A61K31/4985
CPC分类号： C07D295/096 , A61K31/495 , A61K31/4965 , C07D215/38 , C07D215/40 , C07D217/22 , C07D241/04 , C07D243/08 , C07D295/135 , C07D307/78 , C07D307/79 , C07D319/18 , C07D333/34 , C07D409/12 , C07D413/12 , C07D471/04 , C07D487/04 , C07D487/08
摘要： The present invention relates to substituted sulfonamide compounds of the general formula (I), wherein P is sulfonamide or amide-substituted sulfonic acid, which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
摘要翻译： 本发明涉及通式（I）的取代磺酰胺化合物，其中P是磺酰胺或酰胺取代的磺酸，该化合物潜在地用于预防和治疗与肥胖，II型糖尿病和/或 中枢神经系统疾病。
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公开(公告)号：US20060009446A1
公开(公告)日：2006-01-12
申请号：US11215173
申请日：2005-08-30
申请人： Ulf Bremberg , Patrizia Caldirola , Annika Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
发明人： Ulf Bremberg , Patrizia Caldirola , Annika Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
IPC分类号： A61K31/551 , A61K31/495 , C07D241/18
CPC分类号： C07D261/10 , C07D215/36 , C07D243/08 , C07D271/12 , C07D295/135 , C07D401/12 , C07D409/04 , C07D409/14 , C07D413/12 , C07D487/04 , C07D487/08
摘要： The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
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公开(公告)号：US20080096873A1
公开(公告)日：2008-04-24
申请号：US11960045
申请日：2007-12-19
申请人： Ulf Bremberg , Patrizia Caldirola , Annika Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
发明人： Ulf Bremberg , Patrizia Caldirola , Annika Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
IPC分类号： A61K31/5513 , A61K31/496 , A61P25/00 , C07D241/04 , C07D243/24 , A61P3/04 , A61K31/4965
CPC分类号： C07D215/36 , C07D243/08 , C07D261/10 , C07D271/12 , C07D295/135 , C07D401/12 , C07D409/04 , C07D409/14 , C07D413/12 , C07D487/04 , C07D487/08
摘要： The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
摘要翻译： 本发明涉及通式（I）或式（II）的取代的双芳基磺酰胺和芳基磺酰胺化合物，该化合物潜在地可用于预防和治疗与肥胖，II型糖尿病和/或病症有关的医学病症 的中枢神经系统。
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公开(公告)号：US20050288275A1
公开(公告)日：2005-12-29
申请号：US11214523
申请日：2005-08-30
申请人： Ulf Bremberg , Patrizia Caldirola , Annika Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
发明人： Ulf Bremberg , Patrizia Caldirola , Annika Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
IPC分类号： A61K31/42 , A61K31/495 , A61K31/496 , A61K31/4985 , A61K31/551 , A61P3/04 , A61P3/10 , A61P43/00 , C07D215/36 , C07D233/56 , C07D243/08 , C07D261/10 , C07D295/12 , C07D295/135 , C07D401/12 , C07D409/14 , C07D413/12 , C07D487/04 , C07D487/08 , A61K31/55
CPC分类号： C07D261/10 , C07D215/36 , C07D243/08 , C07D271/12 , C07D295/135 , C07D401/12 , C07D409/04 , C07D409/14 , C07D413/12 , C07D487/04 , C07D487/08
摘要： The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
摘要翻译： 本发明涉及通式（I）或式（II）的取代的双芳基磺酰胺和芳基磺酰胺化合物，该化合物潜在地可用于预防和治疗与肥胖，II型糖尿病和/或病症有关的医学病症 的中枢神经系统。
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公开(公告)号：US07319097B2
公开(公告)日：2008-01-15
申请号：US11214523
申请日：2005-08-30
申请人： Ulf Bremberg , Patrizia Caldirola , Annika J. Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
发明人： Ulf Bremberg , Patrizia Caldirola , Annika J. Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
IPC分类号： A61P3/10
CPC分类号： C07D261/10 , C07D215/36 , C07D243/08 , C07D271/12 , C07D295/135 , C07D401/12 , C07D409/04 , C07D409/14 , C07D413/12 , C07D487/04 , C07D487/08
摘要： The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system
摘要翻译： 本发明涉及通式（I）或式（II）的取代的双芳基磺酰胺和芳基磺酰胺化合物，该化合物潜在地可用于预防和治疗与肥胖，II型糖尿病和/或病症有关的医学病症 的中枢神经系统
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公开(公告)号：US07173035B2
公开(公告)日：2007-02-06
申请号：US10143335
申请日：2002-05-10
申请人： Ulf Bremberg , Patrizia Caldirola , Annika J. Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
发明人： Ulf Bremberg , Patrizia Caldirola , Annika J. Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
IPC分类号： A61P25/00 , A61K31/497 , A61K31/4965 , C07D401/00 , C07D241/00
CPC分类号： C07D261/10 , C07D215/36 , C07D243/08 , C07D271/12 , C07D295/135 , C07D401/12 , C07D409/04 , C07D409/14 , C07D413/12 , C07D487/04 , C07D487/08
摘要： The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
摘要翻译： 本发明涉及通式（I）或式（II）的取代的双芳基磺酰胺和芳基磺酰胺化合物，该化合物潜在地可用于预防和治疗与肥胖，II型糖尿病和/或病症有关的医学病症 的中枢神经系统。
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公开(公告)号：US07718650B2
公开(公告)日：2010-05-18
申请号：US11960045
申请日：2007-12-19
申请人： Ulf Bremberg , Patrizia Caldirola , Annika J. Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
发明人： Ulf Bremberg , Patrizia Caldirola , Annika J. Jensen , Gary Johansson , Lori Sutin , Andrew Mott , Jan Tejbrant
IPC分类号： C07D241/36 , C07D487/02 , A61K31/495 , A61K31/40 , A61P25/08 , A61P25/22 , A61P25/24 , A61P25/28 , A61P3/10
CPC分类号： C07D215/36 , C07D243/08 , C07D261/10 , C07D271/12 , C07D295/135 , C07D401/12 , C07D409/04 , C07D409/14 , C07D413/12 , C07D487/04 , C07D487/08
摘要： The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.
摘要翻译： 本发明涉及通式（I）或式（II）的取代的双芳基磺酰胺和芳基磺酰胺化合物，该化合物潜在地可用于预防和治疗与肥胖，II型糖尿病和/或病症有关的医学病症 的中枢神经系统。
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