公开(公告)号：US5048322A

公开(公告)日：1991-09-17

申请号：US402327

申请日：1989-09-05

申请人： Joseph F. Hiller ,  Terrence McCabe ,  Paul L. Morabito

发明人： Joseph F. Hiller ,  Terrence McCabe ,  Paul L. Morabito

IPC分类号： G01N30/02 ,  G01N30/08 ,  G01N30/10 ,  G01N30/12 ,  G01N30/16 ,  G01N30/30

CPC分类号： G01N30/16 ,  G01N30/08 ,  G01N30/30 ,  G01N2030/025 ,  G01N2030/085 ,  G01N2030/165 ,  G01N2030/167 ,  G01N2030/3046 ,  G01N2030/3069 ,  G01N2030/3084 ,  G01N30/10

摘要： The invention describes a large volume on-column gas chromatographic method for analyzing trace levels of high molecular weight and polar compounds in a sample and an apparatus for performing the method. A column inlet coupled to an analytical column is heated rapidly to concentrate difficult to chromatograph compounds onto the analytical column resulting in an increase in the detectability of the compounds.

摘要翻译： 本发明描述了用于分析样品中痕量水平的高分子量和极性化合物的大容量柱内气相色谱法和用于实施该方法的装置。 与分析柱相连的色谱柱入口被快速加热，难以将色谱化合物浓缩到分析柱上，导致化合物的可检测性增加。

公开(公告)号：US5001071A

公开(公告)日：1991-03-19

申请号：US254538

申请日：1988-10-06

申请人： Paul L. Morabito ,  Joseph F. Hiller ,  Terrence McCabe ,  Thomas L. Peters

发明人： Paul L. Morabito ,  Joseph F. Hiller ,  Terrence McCabe ,  Thomas L. Peters

IPC分类号： G01N30/16

CPC分类号： G01N30/16 ,  G01N2030/165

摘要： A method for on-column injection of large sample volumes using the retention gap technique in capillary gas chromatography for sample components of interest that would be obscured by the large solvent peak otherwise inherent in the technique. This interference from the large solvent peak is removed by venting carrier flow from the retention gap to waste for a limited time, long enough to discard much of the solvent without serious loss of the sample component of interest.

摘要翻译： 使用保留间隙技术在毛细管气相色谱法中对目标样品组分进行柱内注射大量样品体积的方法，其将被技术中固有的大溶剂峰所掩蔽。 来自大溶剂峰的这种干扰通过将载体流从保持​​间隙排出到废物一段有限的时间来消除，足够长的时间来丢弃大部分溶剂，而不会使感兴趣的样品组分严重损失。

公开(公告)号：US5338514A

公开(公告)日：1994-08-16

申请号：US111808

申请日：1993-08-25

申请人： Paul L. Morabito ,  Terrence McCabe ,  Joseph F. Hiller

发明人： Paul L. Morabito ,  Terrence McCabe ,  Joseph F. Hiller

IPC分类号： G01N30/02 ,  G01N30/10 ,  G01N30/12 ,  G01N30/16 ,  G01N30/38 ,  G01N30/72 ,  G01N30/00

CPC分类号： G01N30/7213 ,  G01N30/12 ,  G01N2030/025 ,  G01N2030/126 ,  G01N2030/165 ,  G01N2030/385 ,  G01N30/10

摘要： Method and apparatus for gas chromatography/mass spectroscopy including a retention gap, a capillary gas chromatography column and a mass spectrometer, the improvement being a valve that facilitates temporarily venting the carrier gas from between the retention gap and the capillary gas chromatography column immediately after the injection of a sample. The valve also facilitates an alternate flow of carrier gas into the mass spectrometer during the venting operation.

摘要翻译： 包括保留间隙，毛细管气相色谱柱和质谱仪的气相色谱/质谱法的方法和装置，其改进是有利于在紧随着保留间隙和毛细管气相色谱柱之后临时排出载气的阀 注射样品。 在排气操作期间，该阀还有助于将载气交替流入质谱仪。

公开(公告)号：US4962042A

公开(公告)日：1990-10-09

申请号：US448410

申请日：1989-12-08

申请人： Paul L. Morabito ,  Richard G. Melcher ,  Joseph F. Hiller ,  Terrence McCabe

发明人： Paul L. Morabito ,  Richard G. Melcher ,  Joseph F. Hiller ,  Terrence McCabe

IPC分类号： G01N30/06 ,  G01N30/14 ,  G01N30/16 ,  G01N30/20 ,  G01N30/30 ,  G01N30/32

CPC分类号： G01N30/14 ,  G01N2030/062 ,  G01N2030/165 ,  G01N2030/3046 ,  G01N2030/324 ,  G01N30/20

摘要： In one embodiment the invention is a method for on-column valved injection gas chromatography by on-column injecting more than 5 microliters and less than one milliliter of sample consisting of a solvent and a component of interest into a retention gap/capiliary column system with an injection valve at a first carrier gas flow rate, followed by a substantially higher carrier gas flow rate to blow the solvent of the sample out of the system at a rapidly increased rate and then a return to a lower flow rate to chromatograph the component of interest. In another embodiment, less than 5 microliters of sample consisting of a solvent and a component of interest is on-column injected into a capillary column using an injection valve and a relatively high column inlet pressure of gas to move the sample from the injection valve into the colunm rapidly and with reduced carryover. Then, the pressure of carrier gas is reduced to a normal pressure for chromatography of the component of interest.

摘要翻译： 在一个实施方案中，本发明是一种柱上带阀注入气相色谱法的方法，其通过柱上注入超过5微升和小于1毫升由溶剂和感兴趣组分组成的样品的保留间隙/毛细管柱系统中， 以第一载气流速的喷射阀，然后以显着更高的载气流速将样品的溶剂以快速增加的速率吹出系统，然后返回到较低的流速以色谱分离 利益。 在另一个实施方案中，使用注射阀和相对较高的柱入口压力将小于5微升由溶剂和感兴趣组分组成的样品柱内注入毛细管柱，以将样品从注射阀移动到 快速，随身携带。 然后，将载气的压力降低至感兴趣组分的色谱法的常压。

公开(公告)号：US20130206579A1

公开(公告)日：2013-08-15

申请号：US13837276

申请日：2013-03-15

申请人： Michael L. Trippeer ,  Timothy C. Frank ,  Patrick H. Au-Yeung ,  Jason L. Bronkema ,  Robin K. Johnston ,  Mukund R. Patel ,  Bruce S. Holden ,  Terrence McCabe ,  Daniel A. Hickman

发明人： Michael L. Trippeer ,  Timothy C. Frank ,  Patrick H. Au-Yeung ,  Jason L. Bronkema ,  Robin K. Johnston ,  Mukund R. Patel ,  Bruce S. Holden ,  Terrence McCabe ,  Daniel A. Hickman

IPC分类号： C07C17/395

CPC分类号： C07C17/395 ,  B01D3/00 ,  B01D3/009 ,  B01D3/34 ,  C07B2200/09 ,  C07C17/383 ,  C07C21/073

摘要： A process for converting a tertiary halogenated hydrocarbons in a tertiary halogenated hydrocarbon-containing stream to a corresponding unhalogenated or less-halogenated unsaturated hydrocarbon product with the release of hydrogen halide involves contacting the tertiary halogenated hydrocarbon with a sorbent-type dehydrohalogenation catalyst in a reaction zone and optionally passing a stripping gas through the reaction zone to remove vapor phase reaction products from the reaction zone. A process for removing a tertiary chlorinated hydrocarbon impurity from 1,3-dichloro-1-propene involves contacting a mixture containing the 1,3-dichloro-1-propene and the tertiary chlorinated hydrocarbon impurity with a dehydrochlorination catalyst effective to catalyze a conversion of the tertiary chlorinated hydrocarbon impurity to a corresponding unchlorinated or less-chlorinated unsaturated hydrocarbon and hydrogen chloride and distilling the 1,3-dichloro-1-propene to produce a purified cis-1,3-dichloro-1-propene fraction and a purified trans-1,3-dichloro-1-propene fraction.

摘要翻译： 在含卤代烃的物流中将叔卤代烃转化为相应的未卤化或低卤化的不饱和烃产物的方法，其中卤化氢的释放包括使叔卤代烃与吸附剂型脱卤化氢催化剂在反应区 并且可选地使汽提气体通过反应区以从反应区除去气相反应产物。 从1,3-二氯-1-丙烯中除去叔氯化烃杂质的方法包括将含有1,3-二氯-1-丙烯和叔氯化烃杂质的混合物与脱氯化氢催化剂接触，该催化剂有效催化转化率 叔氯化烃杂质转化成相应的未氯化或较少氯化的不饱和烃和氯化氢并蒸馏1,3-二氯-1-丙烯以产生纯化的顺式-1,3-二氯-1-丙烯馏分和纯化的反式 -1,3-二氯-1-丙烯馏分。

公开(公告)号：US20130206578A1

公开(公告)日：2013-08-15

申请号：US13835951

申请日：2013-03-15

申请人： Michael L. Trippeer ,  Timothy C. Frank ,  Patrick H. Au-Yeung ,  Jason L. Bronkema ,  Robin K. Johnston ,  Mukund R. Patel ,  Bruce S. Holden ,  Terrence McCabe ,  Daniel A. Hickman

发明人： Michael L. Trippeer ,  Timothy C. Frank ,  Patrick H. Au-Yeung ,  Jason L. Bronkema ,  Robin K. Johnston ,  Mukund R. Patel ,  Bruce S. Holden ,  Terrence McCabe ,  Daniel A. Hickman

IPC分类号： C07C17/395

CPC分类号： C07C17/395 ,  B01D3/00 ,  B01D3/009 ,  B01D3/34 ,  C07B2200/09 ,  C07C17/383 ,  C07C21/073

摘要： A process for converting a tertiary halogenated hydrocarbons in a tertiary halogenated hydrocarbon-containing stream to a corresponding unhalogenated or less-halogenated unsaturated hydrocarbon product with the release of hydrogen halide involves contacting the tertiary halogenated hydrocarbon with a sorbent-type dehydrohalogenation catalyst in a reaction zone and optionally passing a stripping gas through the reaction zone to remove vapor phase reaction products from the reaction zone. A process for removing a tertiary chlorinated hydrocarbon impurity from 1,3-dichloro-1-propene involves contacting a mixture containing the 1,3-dichloro--propene and the tertiary chlorinated hydrocarbon impurity with a dehydrochlorination catalyst effective to catalyze a conversion of the tertiary chlorinated hydrocarbon impurity to a corresponding unchlorinated or less-chlorinated unsaturated hydrocarbon and hydrogen chloride and distilling the 1,3-dichloro-1-propene to produce a purified cis-1,3-dichloro- 1-propene fraction and a purified trans-1,3-dichloro-1-propene fraction.

摘要翻译： 在含卤代烃的物流中将叔卤代烃转化为相应的未卤化或低卤化的不饱和烃产物的方法，其中卤化氢的释放包括使叔卤代烃与吸附剂型脱卤化氢催化剂在反应区 并且可选地使汽提气体通过反应区以从反应区除去气相反应产物。 从1,3-二氯-1-丙烯中除去叔氯化烃杂质的方法包括使含有1,3-二氯丙烯和叔氯代烃杂质的混合物与脱氯化氢催化剂接触，该催化剂有效地催化 将叔氯化烃杂质加入到相应的未氯化或较少氯化的不饱和烃和氯化氢中并蒸馏1,3-二氯-1-丙烯以产生纯化的顺式-1,3-二氯-1-丙烯级分和纯化的反式 - 1,3-二氯-1-丙烯馏分。

公开(公告)号：US08449729B2

公开(公告)日：2013-05-28

申请号：US12803345

申请日：2010-06-24

申请人： Michael L. Trippeer ,  Timothy C. Frank ,  Patrick H. Au-Yeung ,  Jason L. Bronkema ,  Robin K. Johnston ,  Mukund R. Patel ,  Bruce S. Holden ,  Terrence McCabe ,  Daniel A. Hickman

发明人： Michael L. Trippeer ,  Timothy C. Frank ,  Patrick H. Au-Yeung ,  Jason L. Bronkema ,  Robin K. Johnston ,  Mukund R. Patel ,  Bruce S. Holden ,  Terrence McCabe ,  Daniel A. Hickman

IPC分类号： B01D3/00 ,  B01D3/34

CPC分类号： C07C17/395 ,  B01D3/00 ,  B01D3/009 ,  B01D3/34 ,  C07B2200/09 ,  C07C17/383 ,  C07C21/073

摘要： A process for converting a tertiary halogenated hydrocarbons in a tertiary halogenated hydrocarbon-containing stream to a corresponding unhalogenated or less-halogenated unsaturated hydrocarbon product with the release of hydrogen halide involves contacting the tertiary halogenated hydrocarbon with a sorbent-type dehydrohalogenation catalyst in a reaction zone and optionally passing a stripping gas through the reaction zone to remove vapor phase reaction products from the reaction zone. A process for removing a tertiary chlorinated hydrocarbon impurity from 1,3-dichloro-1-propene involves contacting a mixture containing the 1,3-dichloro-1-propene and the tertiary chlorinated hydrocarbon impurity with a dehydrochlorination catalyst effective to catalyze a conversion of the tertiary chlorinated hydrocarbon impurity to a corresponding unchlorinated or less-chlorinated unsaturated hydrocarbon and hydrogen chloride and distilling the 1,3-dichloro-1-propene to produce a purified cis-1,3-dichloro-1-propene fraction and a purified trans-1,3-dichloro-1-propene fraction.

公开(公告)号：US20110005914A1

公开(公告)日：2011-01-13

申请号：US12803345

申请日：2010-06-24

申请人： Michael L. Trippeer ,  Timothy C. Frank ,  Patrick H. Au-Yeung ,  Jason L. Bronkema ,  Robin K. Johnston ,  Mukund R. Patel ,  Bruce S. Holden ,  Terrence McCabe ,  Daniel A. Hickman

发明人： Michael L. Trippeer ,  Timothy C. Frank ,  Patrick H. Au-Yeung ,  Jason L. Bronkema ,  Robin K. Johnston ,  Mukund R. Patel ,  Bruce S. Holden ,  Terrence McCabe ,  Daniel A. Hickman

IPC分类号： B01D3/34

CPC分类号： C07C17/395 ,  B01D3/00 ,  B01D3/009 ,  B01D3/34 ,  C07B2200/09 ,  C07C17/383 ,  C07C21/073

摘要： A process for converting a tertiary halogenated hydrocarbons in a tertiary halogenated hydrocarbon-containing stream to a corresponding unhalogenated or less-halogenated unsaturated hydrocarbon product with the release of hydrogen halide involves contacting the tertiary halogenated hydrocarbon with a sorbent-type dehydrohalogenation catalyst in a reaction zone and optionally passing a stripping gas through the reaction zone to remove vapor phase reaction products from the reaction zone. A process for removing a tertiary chlorinated hydrocarbon impurity from 1,3-dichloro-1-propene involves contacting a mixture containing the 1,3-dichloro-1-propene and the tertiary chlorinated hydrocarbon impurity with a dehydrochlorination catalyst effective to catalyze a conversion of the tertiary chlorinated hydrocarbon impurity to a corresponding unchlorinated or less-chlorinated unsaturated hydrocarbon and hydrogen chloride and distilling the 1,3-dichloro-1-propene to produce a purified cis-1,3-dichloro-1-propene fraction and a purified trans-1,3-dichloro-1-propene fraction.

摘要翻译： 在含卤代烃的物流中将叔卤代烃转化为相应的未卤化或低卤化的不饱和烃产物的方法，其中卤化氢的释放包括使叔卤代烃与吸附剂型脱卤化氢催化剂在反应区 并且可选地使汽提气体通过反应区以从反应区除去气相反应产物。 从1,3-二氯-1-丙烯中除去叔氯化烃杂质的方法包括将含有1,3-二氯-1-丙烯和叔氯化烃杂质的混合物与脱氯化氢催化剂接触，该催化剂有效催化转化率 叔氯化烃杂质转化成相应的未氯化或较少氯化的不饱和烃和氯化氢并蒸馏1,3-二氯-1-丙烯以产生纯化的顺式-1,3-二氯-1-丙烯馏分和纯化的反式 -1,3-二氯-1-丙烯馏分。