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公开(公告)号：US06372889B1
公开(公告)日：2002-04-16
申请号：US09294531
申请日：1999-04-19
申请人： Paul O. Sheppard , Darrell C. Conklin , Theresa M. Farrah , Mark F. Maurer , Angelika Grossmann
发明人： Paul O. Sheppard , Darrell C. Conklin , Theresa M. Farrah , Mark F. Maurer , Angelika Grossmann
IPC分类号： C07K1447
摘要： The present invention relates to polynucleotide and polypeptide molecules for ZTMPO-1, a novel soluble protein with homology to emerin and the thymopoietins. The polypeptides, and polynucleotides encoding them are useful for modulating cellular proliferation and differentiation and may be used for diagnostic purposes. The present invention also includes antibodies to the ZTMPO-1 polypeptides.
摘要翻译： 本发明涉及用于ZTMPO-1的多核苷酸和多肽分子，其与emerin和胸腺细胞生成素具有同源性的新型可溶性蛋白质。 多肽和编码它们的多核苷酸可用于调节细胞增殖和分化，并可用于诊断目的。 本发明还包括针对ZTMPO-1多肽的抗体。
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公开(公告)号：US20110082094A1
公开(公告)日：2011-04-07
申请号：US12891586
申请日：2010-09-27
IPC分类号： A61K38/16 , C07H21/04 , C07K14/00 , C07K16/18 , C07H21/00 , C07K7/08 , A61K38/10 , A61P43/00
CPC分类号： A61K39/3955 , C07K14/52
摘要： A mammalian cytokine-like polypeptide, called Zcyto10, polynucleotides encoding the same, antibodies which specifically bind to the polypeptide, and anti-idiotypic antibodies which bind to the antibodies. Zcyto10 is useful for promoting the healing of wounds and for stimulating the proliferation of platelets.
摘要翻译： 称为Zcyto10的哺乳动物细胞因子样多肽，编码该多核苷酸的多核苷酸，与该多肽特异性结合的抗体，以及与抗体结合的抗独特型抗体。 Zcyto10可用于促进伤口愈合和刺激血小板增殖。
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公开(公告)号：US07829089B2
公开(公告)日：2010-11-09
申请号：US12552239
申请日：2009-09-01
IPC分类号： C07K16/24 , A61K39/395 , C12N5/12
CPC分类号： A61K39/3955 , C07K14/52
摘要： A mammalian cytokine-like polypeptide, called Mammalian Cytokine-like polypeptide-10, (Zcyto10), polynucleotides encoding the same, antibodies which specifically bind to the polypeptide, and anti-idiotypic antibodies which bind to the antibodies. Zcyto10 is useful for promoting the healing of wounds and for stimulating the proliferation of platelets.
摘要翻译： 哺乳动物细胞因子样多肽，称为哺乳动物细胞因子样多肽-10（Zcyto10），编码该多聚核苷酸的多核苷酸，与该多肽特异性结合的抗体，以及与抗体结合的抗独特型抗体。 Zcyto10可用于促进伤口愈合和刺激血小板增殖。
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公开(公告)号：US20100015703A1
公开(公告)日：2010-01-21
申请号：US12552239
申请日：2009-09-01
CPC分类号： A61K39/3955 , C07K14/52
摘要： A mammalian cytokine-like polypeptide, called Mammalian Cytokine-like polypeptide-10, (Zcyto10), polynucleotides encoding the same, antibodies which specifically bind to the polypeptide, and anti-idiotypic antibodies which bind to the antibodies. Zcyto10 is useful for promoting the healing of wounds and for stimulating the proliferation of platelets.
摘要翻译： 哺乳动物细胞因子样多肽，称为哺乳动物细胞因子样多肽-10（Zcyto10），编码该多聚核苷酸的多核苷酸，与该多肽特异性结合的抗体，以及与抗体结合的抗独特型抗体。 Zcyto10可用于促进伤口愈合和刺激血小板增殖。
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公开(公告)号：US07601830B2
公开(公告)日：2009-10-13
申请号：US12111798
申请日：2008-04-29
CPC分类号： A61K39/3955 , C07K14/52
摘要： A mammalian cytokine-like polypeptide, called Mammalian Cytokine-like polypeptide-10, (Zcyto10), polynucleotides encoding the same, antibodies which specifically bind to the polypeptide, and anti-idiotypic antibodies which bind to the antibodies. Zcyto10 is useful for promoting the healing of wounds and for stimulating the proliferation of platelets.
摘要翻译： 哺乳动物细胞因子样多肽，称为哺乳动物细胞因子样多肽-10（Zcyto10），编码该多聚核苷酸的多核苷酸，与该多肽特异性结合的抗体，以及与抗体结合的抗独特型抗体。 Zcyto10可用于促进伤口愈合和刺激血小板增殖。
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公开(公告)号：US20080207886A1
公开(公告)日：2008-08-28
申请号：US12111798
申请日：2008-04-29
IPC分类号： C07H21/04
CPC分类号： A61K39/3955 , C07K14/52
摘要： A mammalian cytokine-like polypeptide, called Mammalian Cytokine-like polypeptide-10, (Zcyto10), polynucleotides encoding the same, antibodies which specifically bind to the polypeptide, and anti-idiotypic antibodies which bind to the antibodies. Zcyto10 is useful for promoting the healing of wounds and for stimulating the proliferation of platelets.
摘要翻译： 哺乳动物细胞因子样多肽，称为哺乳动物细胞因子样多肽-10（Zcyto10），编码该多聚核苷酸的多核苷酸，与该多肽特异性结合的抗体，以及与抗体结合的抗独特型抗体。 Zcyto10可用于促进伤口愈合和刺激血小板增殖。
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公开(公告)号：US08124739B2
公开(公告)日：2012-02-28
申请号：US12891586
申请日：2010-09-27
IPC分类号： C07K16/24
CPC分类号： A61K39/3955 , C07K14/52
摘要： A mammalian cytokine-like polypeptide, called Zcyto10, polynucleotides encoding the same, antibodies which specifically bind to the polypeptide, and anti-idiotypic antibodies which bind to the antibodies. Zcyto10 is useful for promoting the healing of wounds and for stimulating the proliferation of platelets.
摘要翻译： 称为Zcyto10的哺乳动物细胞因子样多肽，编码该多核苷酸的多核苷酸，与该多肽特异性结合的抗体，以及与抗体结合的抗独特型抗体。 Zcyto10可用于促进伤口愈合和刺激血小板增殖。
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公开(公告)号：US07271246B2
公开(公告)日：2007-09-18
申请号：US11458883
申请日：2006-07-20
CPC分类号： A61K39/3955 , C07K14/52
摘要： A mammalian cytokine-like polypeptide, called Mammalian Cytokine-like polypeptide-10, (Zcyto10), polynucleotides encoding the same, antibodies which specifically bind to the polypeptide, and anti-idiotypic antibodies which bind to the antibodies. Zcyto10 is useful for promoting the healing of wounds and for stimulating the proliferation of platelets.
摘要翻译： 哺乳动物细胞因子样多肽，称为哺乳动物细胞因子样多肽-10（Zcyto10），编码该多聚核苷酸的多核苷酸，与该多肽特异性结合的抗体，以及与抗体结合的抗独特型抗体。 Zcyto10可用于促进伤口愈合和刺激血小板增殖。
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公开(公告)号：US07119175B2
公开(公告)日：2006-10-10
申请号：US10748484
申请日：2003-12-29
IPC分类号： C07K16/24
CPC分类号： A61K39/3955 , C07K14/52
摘要： A mammalian cytokine-like polypeptide, called Zcyto10, polynucleotides encoding the same, antibodies which specifically bind to the polypeptide, and anti-idiotypic antibodies which bind to the antibodies. Zcyto10 is useful for promoting the healing of wounds and for stimulating the proliferation of platelets.
摘要翻译： 称为Zcyto10的哺乳动物细胞因子样多肽，编码该多核苷酸的多核苷酸，与该多肽特异性结合的抗体，以及与抗体结合的抗独特型抗体。 Zcyto10可用于促进伤口愈合和刺激血小板增殖。
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公开(公告)号：US20080233114A1
公开(公告)日：2008-09-25
申请号：US11752197
申请日：2007-05-22
申请人： Theresa A. Deisher , Darrell C. Conklin , Fenella C. Raymond , Thomas R. Bukowski , Susan D. Holderman , Paul O. Sheppard
发明人： Theresa A. Deisher , Darrell C. Conklin , Fenella C. Raymond , Thomas R. Bukowski , Susan D. Holderman , Paul O. Sheppard
IPC分类号： A61K39/395 , C07K16/00 , A61P29/00
CPC分类号： C07K14/50 , A61K38/00 , C07K2319/00
摘要： The present invention relates to polynucleotide and polypeptide molecules for zFGF5 a novel member of the FGF family. The polypeptides, and polynucleotides encoding them, are proliferative for muscle cells, in particular cardiac cells and may be used for remodeling cardiac tissue and improving cardiac function. The present invention also includes antibodies to the zFGF5 polypeptides.
摘要翻译： 本发明涉及zFGF5的多核苷酸和多肽分子，其是FGF家族的新成员。 多肽和编码它们的多核苷酸对于肌肉细胞，特别是心脏细胞是增殖性的，并且可以用于重建心脏组织和改善心脏功能。 本发明还包括对zFGF5多肽的抗体。
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