公开(公告)号：US07567346B2

公开(公告)日：2009-07-28

申请号：US11363938

申请日：2006-03-01

申请人： Pavel A. Fomitchov ,  Eugene Barash ,  Ahmad Yetka ,  Joseph Masino, III

发明人： Pavel A. Fomitchov ,  Eugene Barash ,  Ahmad Yetka ,  Joseph Masino, III

IPC分类号： G01N21/25

CPC分类号： G01N21/6458 ,  G01N21/47 ,  G01N2201/0407 ,  G01N2201/1042 ,  G02B21/0048 ,  G02B21/0076 ,  G02B21/367

摘要： A system and method for multimode imaging of at least one sample is disclosed. The system includes at least one light source; an optical system selected responsive to a mode of operation of the imaging system; and a detector capable of selective reading of pixels. The at least one sample is moved elative to the optical system using a sample movement technique selected from the group consisting of step sample moving and continuous sample moving. The method includes the steps of (1) selecting a mode of operation for the imaging system; (2) transmitting light from at least one light source through an optical system selected in response to the mode of operation for the imaging system; (3) moving the at least one sample relative to the optical system using a sample movement technique selected from the group consisting of step sample moving and continuous sample moving; and (4) selectively reading pixels with a detector.

摘要翻译： 公开了一种用于至少一个样品的多模成像的系统和方法。 该系统包括至少一个光源; 响应于成像系统的操作模式选择的光学系统; 以及能够选择性地读取像素的检测器。 使用选自步骤样品移动和连续样品移动的样品移动技术将至少一个样品移动到光学系统。 该方法包括以下步骤：（1）选择成像系统的操作模式; （2）从至少一个光源透射通过响应于成像系统的操作模式选择的光学系统的光; （3）使用选自步骤样品移动和连续样品移动的样本移动技术来移动所述至少一个样品相对于所述光学系统; 和（4）用检测器选择性地读取像素。

公开(公告)号：US20120075695A1

公开(公告)日：2012-03-29

申请号：US12889087

申请日：2010-09-23

申请人： Christopher A. DeBlasis ,  Michael C. Montalto ,  Matthew S. Zelinski ,  Joseph Masino, III

发明人： Christopher A. DeBlasis ,  Michael C. Montalto ,  Matthew S. Zelinski ,  Joseph Masino, III

IPC分类号： G02B21/26

CPC分类号： B01L9/52 ,  B01L2300/0822 ,  G01N2035/00138 ,  G02B21/26

摘要： Pathology specimen slides are positively located on trays, and picked and placed by an auto-loader. The trays are received in a rack in tiers accessed by an auto-loader that moves the slides between the trays and a digital imaging microscope. The trays can have rows of receptacles for slides with standoff structures spacing the slides above a tray bottom. Lateral and endwise partitions defining the receptacles are inclined oppositely inwardly for guiding a slide into the predetermined position on the tray. The autoloader has a manipulator that grasps the ends of slides presented in a front row, and can reach over the front row to grasp slides in one or more rows beyond the front. The manipulator lifts the slide between the inclined surfaces of the partitions, loads and later retrieves the slide from the microscope and replaces the slide in the holder.

摘要翻译： 病理标本载玻片位于托盘上，由自动装载机拾取并放置。 托盘通过自动装载机访问的层架接收，将托架和数字成像显微镜之间的滑块移动。 托盘可以具有一排插座，用于具有间隔结构的滑块，将托盘底部的滑块间隔开。 限定容器的横向和纵向隔板相对地向内倾斜以将滑块引导到托盘上的预定位置。 自动装载机具有抓握在前排中呈现的滑块的端部的操纵器，并且可以到达前排，以在前面的一行或多行中抓取幻灯片。 操纵器将滑块提升到分隔壁的倾斜表面之间，然后加载，然后从显微镜中取出载玻片并取代支架中的滑块。