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公开(公告)号：US5152993A
公开(公告)日：1992-10-06
申请号：US555987
申请日：1990-07-18
CPC分类号： C01B15/047 , A61K33/40 , A61L27/06 , A61L27/306 , A61L27/54 , A61F2310/00023 , A61L2300/252 , A61L2300/404 , A61L2300/412 , A61L2300/414 , A61L2300/606 , Y10S623/92
摘要： A method of preparing an implant body in order to optimize the healing time of said implant, comprising bringing the implant body for a limited period of time into contact with a hydrogen peroxide solution at least on the surfaces intended to come into contact with surrounding tissue when implanted, the treated surfaces being cleaned by rinsing. The treatment of the implant surface with hydrogen peroxide can be supplemented with incorporation of biomolecules, such as peptides, proteins and steroids, and also other substances such as inorganic ions and crystals. The compounds to be coupled to the implant surface may promote the healing and/or binding of the surrounding tissue.
摘要翻译： 一种制备植入物体的方法，以便优化所述植入物的愈合时间，包括使植入体在有限的时间段内至少在与周围组织接触的表面上与过氧化氢溶液接触， 被处理的表面通过冲洗来清洁。 用过氧化氢处理植入物表面可以补充生物分子如肽，蛋白质和类固醇以及其它物质如无机离子和晶体的并入。 要耦合到植入物表面的化合物可以促进周围组织的愈合和/或结合。
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2.发明授权
公开(公告)号：US5045318A
公开(公告)日：1991-09-03
申请号：US411466
申请日：1989-09-19
IPC分类号： A61K33/24 , A61K33/40 , A61L27/00 , A61L27/30 , A61L27/54 , A61P17/00 , A61P29/00 , A61P31/04 , C01B15/047
CPC分类号： A61L27/306 , A61K33/40 , A61L27/54 , C01B15/047 , A61L2300/102 , A61L2300/11 , A61L2300/41
摘要： The reaction product of H.sub.2 O.sub.2 and metallic titanium, a titanium peroxy radical gel, exhibits oxidizing and anti-inflammatory effects and is used, for instance, as a biocompatible oxidant, an anti-inflammatory agent or in vitro coating of an implant body. The gel-like product is produced by treating metallic titanium with H.sub.2 O.sub.2.
摘要翻译： PCT No.PCT / SE89 / 00015 Sec。 371日期：1989年9月19日 102（e）1989年9月19日PCT 1989年1月19日PCT PCT。 出版物WO89 / 06548 日期：1989年7月27日。H 2 O 2与金属钛（过氧基自由基凝胶）的反应产物表现出氧化和抗炎作用，例如用作生物相容性氧化剂，抗炎剂或体外涂层 的植入体。 通过用H 2 O 2处理金属钛制成凝胶状产物。
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公开(公告)号：US20150139913A1
公开(公告)日：2015-05-21
申请号：US14405489
申请日：2013-05-29
IPC分类号： A61K49/04
CPC分类号： A61K49/0419 , A61K49/0414
摘要： The present invention describes particles of titanium, titanium alloy, at least one type of titanium oxide or a combination thereof, wherein at least a substantial amount of the particles are of micrometer-millimeter size and are non-spherical, for use as an X-ray contrast agent. The irregular shapes and/or internal pores and cavities of said particles lead to a prolonged retention time in the gastrointestinal tract leading to a longer time period available for X-ray examination. Further, the particles are not only chemically inert, they also exhibit an anti-inflammatory and anti-bacterial effect on the surrounding tissue.
摘要翻译： 本发明描述了钛，钛合金，至少一种类型的氧化钛或其组合的颗粒，其中至少大量的颗粒是微米大小并且是非球形的，用作X- 射线造影剂。 所述颗粒的不规则形状和/或内部孔和空腔导致在胃肠道中延长的保留时间，导致可用于X射线检查的较长时间段。 此外，颗粒不仅是化学惰性的，它们还对周围组织表现出抗炎和抗细菌作用。
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公开(公告)号：US4781694A
公开(公告)日：1988-11-01
申请号：US832787
申请日：1986-02-26
CPC分类号： A61M39/0247 , A61M2039/0255 , A61M2039/0261 , A61M2039/0276 , A61M2039/0279
摘要： The present invention relates to a device for providing a permanent pathway between the abdominal cavity and/or organ located in the abdominal cavity and the exterior of the body. The device is made of commercially pure titanium or at least coated with titanium on the surfaces which directly contact the abdominal wall tissue. The device comprises a first anchorage portion, designed for implantation into the connective tissue of the abdomen during the first operation, a covering screw with plug for blocking of the central opening in the anchorage portion during the healing phase and a skin penetration portion in the form of a titanium tube for connection to the anchorage portion during the second operation after prior removal of the covering screw with plug.
摘要翻译： 本发明涉及一种用于在位于腹腔和腹部外部的腹腔和/或器官之间提供永久路径的装置。 该装置由直接接触腹壁组织的表面上由商业纯钛制成或至少涂覆有钛。 所述装置包括第一锚固部分，其设计用于在第一操作期间植入到腹部的结缔组织中，具有用于在愈合阶段期间阻挡锚固部分中的中心开口的塞子的覆盖螺钉和形式的皮肤穿透部分 的钛管，用于在先前用塞子去除覆盖螺钉之后在第二操作期间连接到锚固部分。
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公开(公告)号：US20150140100A1
公开(公告)日：2015-05-21
申请号：US14405558
申请日：2013-05-29
CPC分类号： A61L15/44 , A61K33/24 , A61L15/18 , A61L15/425 , A61L2300/102 , A61L2300/404 , A61L2300/41 , A61L2300/412 , A61L2300/602 , C01G23/04 , C01G23/047 , C01P2004/61
摘要： The present invention describes a medical device comprising a set of particles of titanium oxide, wherein at least a substantial amount of the particles are of micrometer—millimeter size, and wherein at least 10 wt % of the titanium oxide is in the amorphous form.
摘要翻译： 本发明描述了一种医疗装置，其包括一组二氧化钛颗粒，其中至少大部分颗粒为微米级，并且其中至少10重量％的氧化钛为无定形形式。
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