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26 条记录 (耗时 0.046 秒)

    Internal combustion engine heat transfer system
    4.
    发明授权
    Internal combustion engine heat transfer system 失效
    内燃机传热系统

    公开(公告)号：US08635860B1

    公开(公告)日：2014-01-28

    申请号：US13358726

    申请日：2012-01-26

    申请人： Ralph P. Robinson

    发明人： Ralph P. Robinson

    IPC分类号： F01N3/00

    CPC分类号： F02B77/11 ,  F01N2260/20

    摘要： A system for reversing heat transfer from an exhaust system assembly on a vehicle comprising an engine block assembly and transaxle assembly operatively connected and located in an engine compartment of an automobile. The system comprises a number one exhaust manifold stay mount, a number two exhaust manifold stay mount, and a front exhaust collector pipe bracket and stay mount. The system comprises an exhaust system with a front exhaust collector pipe located beneath the engine block assembly. The system comprises an engine block assembly heat shield with a cross-section generally comprising the shape of a “U” that is located next to the surface of the engine block assembly. The engine block assembly heat shield is located over and overlays the front exhaust collector pipe bracket and stay mount, the number one exhaust manifold stay mount, and the number two exhaust manifold stay mount.

    摘要翻译： 一种用于反转来自车辆上的排气系统组件的热传递的系统，包括可操作地连接并位于汽车的发动机室中的发动机缸体组件和变速驱动桥组件。 该系统包括一个排气歧管支架，两个排气歧管支架和一个前排气收集管支架，并支撑。 该系统包括具有位于发动机缸体组件下方的前排气收集管的排气系统。 该系统包括具有通常包括邻近发动机缸体组件的表面的“U”形状的横截面的发动机缸体组件隔热罩。 发动机机组组合隔热罩位于前排气收集管支架和支架上，排气歧管支架一号和排气歧管两座支架上。

    Arylsulfonylamino hydroxamic acid derivatives
    8.
    发明授权
    Arylsulfonylamino hydroxamic acid derivatives 失效
    芳基磺酰氨基异羟肟酸衍生物

    公开(公告)号：US6107337A

    公开(公告)日：2000-08-22

    申请号：US130922

    申请日：1998-08-06

    申请人： Ralph P. Robinson

    发明人： Ralph P. Robinson

    IPC分类号： C07C311/19 ,  C07C311/20 ,  A61K31/35 ,  A61K31/216 ,  A61K31/50 ,  A61K31/5375

    CPC分类号： C07C311/19 ,  C07C311/20 ,  C07C2101/08 ,  Y10S514/824 ,  Y10S514/921

    摘要： A compound of the formula ##STR1## wherein n, X, R.sup.3, R.sup.4 and Ar are as defined above, useful in the treatment of a condition selected from the group consisting of arthritis, cancer, tissue ulceration, restenosis, periodontal disease, epidermolysis bullosa, scleritis, bone resorption, loosening of artificial joint implants, atherosclerosis, multiple sclerosis, occular angiogenisis and other diseases characterized by matrix metalloproteinase activity, AIDS, sepsis, septic shock and other diseases involving the production of TNF.

    摘要翻译： 下式的化合物其中n，X，R 3，R 4和Ar如上定义，可用于治疗选自以下的病症：选自由关节炎，癌症，组织溃疡，再狭窄，牙周病，大疱性表皮松解症，巩膜炎， 骨吸收，人工关节植入物的松动，动脉粥样硬化，多发性硬化，眼部血管生成和其他以基质金属蛋白酶活性为特征的疾病，艾滋病，败血症，败血症休克等涉及TNF产生的疾病。

    4,5,6,11-tetrahydrobenzo [6,7] cycloocta [1,2-b]thiophen-6,11-imines and 6,11-dihydrobenzo [6,7] cycloocta [1,2-b] thiophen-6,11-imines
    9.
    发明授权
    4,5,6,11-tetrahydrobenzo [6,7] cycloocta [1,2-b]thiophen-6,11-imines and 6,11-dihydrobenzo [6,7] cycloocta [1,2-b] thiophen-6,11-imines 失效
    4,5,6,11-四氢苯并[6,7]环辛[1,2-b]噻吩-6,11-亚胺和6,11-二氢苯并[6,7]环辛[1,2-b] 6,11-亚胺

    公开(公告)号：US5260309A

    公开(公告)日：1993-11-09

    申请号：US828892

    申请日：1992-01-29

    申请人： Ralph P. Robinson

    发明人： Ralph P. Robinson

    IPC分类号： C07D495/18 ,  C07D513/22 ,  A61K31/38

    CPC分类号： C07D495/18

    摘要： The present invention relates to compounds of the formula ##STR1## wherein the broken line represents a saturated or an olefinic bond, R.sup.1 and R.sup.4 are each hydrogen or C.sub.1 to C.sub.6 alkyl, and R.sup.2 and R.sup.3 are each hydrogen, C.sub.1 to C.sub.6 alkyl, halogen, C.sub.1 to C.sub.6 alkoxy or C.sub.1 to C.sub.6 alkylthio, and pharmaceutically acceptable salts thereof, pharmaceutical compounds containing the same, methods of preparing the foregoing compounds, and to novel intermediates in the preparation of the foregoing compounds. These compounds are useful as agents in the prevention of neuronal damage in the brain following cerebral ischemia and during the progression of Alzheimer's disease and also as anticonvulsants.

    摘要翻译： PCT No.PCT / US89 / 02387第 371日期1992年1月29日 102（e）日期1992年1月29日PCT提交1989年6月1日PCT公布。 WO90 / 15060 PCT出版物 1990年12月13日。本发明涉及下式化合物：其中虚线代表饱和或烯键，R 1和R 4各自为氢或C 1至C 6烷基，R 2和R 3各自为氢 C 1〜C 6烷基，卤素，C 1〜C 6烷氧基或C 1〜C 6烷硫基，及其药学上可接受的盐，含有该化合物的药物组合物，制备上述化合物的方法，以及制备上述化合物的新中间体。 这些化合物可用作预防脑缺血后和阿尔茨海默氏病进程期间脑内神经元损伤以及作为抗惊厥药的药剂。