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公开(公告)号：US20080197272A1
公开(公告)日：2008-08-21
申请号：US12098584
申请日：2008-04-07
IPC分类号： G01J3/50
CPC分类号： G01N21/05 , G01N21/645 , G01N21/65 , G01N21/658 , G01N2021/0346 , G01N2021/1734 , G01N2021/6421 , G01N2021/6482
摘要： A fluidic structure includes a channel and along the channel is a series of sensing components to obtain information about objects traveling within the channel, such as droplets or other objects carried by fluid. At least one sensing component includes a set of cells of a photosensor array. The set of cells photosense a range of photon energies that emanate from objects, and include a subset of cells that photosense within subranges. A processor can receive information about objects from the sensing components and use it to obtain spectral information. The processor can perform an initial analysis using information from one set of sensing components and, based on the results, control a fluidic device in the channel, such as a gate, to retain objects, such as for concentration and more detailed analysis by other sensing components, or to purge objects from the channel.
摘要翻译： 流体结构包括通道，并且沿着通道是一系列感测部件，以获得关于在通道内行进的物体的信息，例如由流体携带的液滴或其它物体。 至少一个感测组件包括一组光电传感器阵列的单元。 该组细胞照射从物体发出的一系列光子能量，并且包括在子范围内的光密度的子集。 处理器可以从感测组件接收关于对象的信息，并使用它来获得光谱信息。 处理器可以使用来自一组感测组件的信息来执行初始分析，并且基于该结果，控制通道（例如门）中的流体装置以保持对象，例如通过其他感测进行浓度和更详细的分析 组件，或从通道清除对象。
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公开(公告)号：US07479625B2
公开(公告)日：2009-01-20
申请号：US12098584
申请日：2008-04-07
IPC分类号： G01J3/50
CPC分类号： G01N21/05 , G01N21/645 , G01N21/65 , G01N21/658 , G01N2021/0346 , G01N2021/1734 , G01N2021/6421 , G01N2021/6482
摘要： A fluidic structure includes a channel and along the channel is a series of sensing components to obtain information about objects traveling within the channel, such as droplets or other objects carried by fluid. At least one sensing component includes a set of cells of a photosensor array. The set of cells photosense a range of photon energies that emanate from objects, and include a subset of cells that photosense within subranges. A processor can receive information about objects from the sensing components and use it to obtain spectral information. The processor can perform an initial analysis using information from one set of sensing components and, based on the results, control a fluidic device in the channel, such as a gate, to retain objects, such as for concentration and more detailed analysis by other sensing components, or to purge objects from the channel.
摘要翻译： 流体结构包括通道，并且沿着通道是一系列感测部件，以获得关于在通道内行进的物体的信息，例如由流体携带的液滴或其它物体。 至少一个感测组件包括一组光电传感器阵列的单元。 该组细胞照射从物体发出的一系列光子能量，并且包括在子范围内的光密度的子集。 处理器可以从感测组件接收关于对象的信息，并使用它来获得光谱信息。 处理器可以使用来自一组感测组件的信息来执行初始分析，并且基于该结果，控制通道（例如门）中的流体装置以保持对象，例如通过其他感测的浓度和更详细的分析 组件，或从通道清除对象。
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公开(公告)号：US07358476B2
公开(公告)日：2008-04-15
申请号：US11315992
申请日：2005-12-22
IPC分类号： G01J3/50
CPC分类号： G01N21/05 , G01N21/645 , G01N21/65 , G01N21/658 , G01N2021/0346 , G01N2021/1734 , G01N2021/6421 , G01N2021/6482
摘要： A fluidic structure includes a channel and along the channel is a series of sensing components to obtain information about objects traveling within the channel, such as droplets or other objects carried by fluid. At least one sensing component includes a set of cells of a photosensor array. The set of cells photosense a range of photon energies that emanate from objects, and include a subset of cells that photosense within subranges. A processor can receive information about objects from the sensing components and use it to obtain spectral information. The processor can perform an initial analysis using information from one set of sensing components and, based on the results, control a fluidic device in the channel, such as a gate, to retain objects, such as for concentration and more detailed analysis by other sensing components, or to purge objects from the channel.
摘要翻译： 流体结构包括通道，并且沿着通道是一系列感测部件，以获得关于在通道内行进的物体的信息，例如由流体携带的液滴或其它物体。 至少一个感测组件包括一组光电传感器阵列的单元。 该组细胞照射从物体发出的一系列光子能量，并且包括在子范围内的光密度的子集。 处理器可以从感测组件接收关于对象的信息，并使用它来获得光谱信息。 处理器可以使用来自一组感测组件的信息来执行初始分析，并且基于结果，控制通道中的流体装置（例如门），以保留对象，例如通过其他感测进行浓度和更详细的分析 组件，或从通道清除对象。
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公开(公告)号：US07811438B2
公开(公告)日：2010-10-12
申请号：US11007121
申请日：2004-12-08
申请人： Meng H. Lean , Armin R. Völkel , Peter Kiesel , Oliver Schmidt , Noble M. Johnson , H. Ben Hsieh
发明人： Meng H. Lean , Armin R. Völkel , Peter Kiesel , Oliver Schmidt , Noble M. Johnson , H. Ben Hsieh
IPC分类号： B03C5/02
CPC分类号： G01N30/0005 , B03C5/028 , G01N30/08
摘要： A flow cell is disclosed for collecting and concentrating a sample dispersed in a flowing medium. The collected sample can be selectively manipulated within the cell by the use of one or more traveling wave grids. The cells are particularly useful as bio-enrichment devices and can be utilized upstream of conventional analytical or detection instruments.
摘要翻译： 公开了用于收集和浓缩分散在流动介质中的样品的流动池。 收集的样品可以通过使用一个或多个行波网格在单元内选择性地操纵。 细胞特别可用作生物富集装置，并可用于常规分析或检测仪器的上游。
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公开(公告)号：US07387892B2
公开(公告)日：2008-06-17
申请号：US10930758
申请日：2004-09-01
IPC分类号： C12M1/34
CPC分类号： B82Y20/00 , G01N33/54373 , H01S5/041 , H01S5/0607 , H01S5/1075 , H01S5/34333 , H01S5/4025
摘要： A compact sensor for detecting the presence of biological or chemical species includes a microdisk laser and a wavelength shift detector. The microdisk laser is coated with a biological or chemical recognition element, which binds preferentially with a target analyte. Because the recognition element and the target analyte adhere to the sidewall surface of the microdisk laser, they increase the effective diameter of the laser, which shifts the output wavelength by a detectable amount. The presence of a wavelength shift indicates the presence of the target analyte, and the magnitude of the wavelength shift corresponds to the mass load of the target analyte on the sidewall surface of the microdisk laser.
摘要翻译： 用于检测生物或化学物质存在的紧凑型传感器包括微盘激光器和波长偏移检测器。 微型体激光器涂覆有与目标分析物优先结合的生物或化学识别元件。 因为识别元件和目标分析物粘附到微盘激光器的侧壁表面，所以它们增加了激光器的有效直径，这将输出波长移动了可检测的量。 波长偏移的存在表示目标分析物的存在，并且波长漂移的大小对应于微盘激光器的侧壁表面上的目标分析物的质量负载。
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公开(公告)号：US20080204709A1
公开(公告)日：2008-08-28
申请号：US12118056
申请日：2008-05-09
IPC分类号： G01N1/00
CPC分类号： B82Y20/00 , G01N33/54373 , H01S5/041 , H01S5/0607 , H01S5/1075 , H01S5/34333 , H01S5/4025
摘要： A compact sensor for detecting the presence of biological or chemical species includes a microdisk laser and a wavelength shift detector. The microdisk laser is coated with a biological or chemical recognition element, which binds preferentially with a target analyte. Because the recognition element and the target analyte adhere to the sidewall surface of the microdisk laser, they increase the effective diameter of the laser, which shifts the output wavelength by a detectable amount. The presence of a wavelength shift indicates the presence of the target analyte, and the magnitude of the wavelength shift corresponds to the mass load of the target analyte on the sidewall surface of the microdisk laser.
摘要翻译： 用于检测生物或化学物质存在的紧凑型传感器包括微盘激光器和波长偏移检测器。 微型体激光器涂覆有与目标分析物优先结合的生物或化学识别元件。 因为识别元件和目标分析物粘附到微盘激光器的侧壁表面，所以它们增加了激光器的有效直径，这将输出波长移动了可检测的量。 波长偏移的存在表示目标分析物的存在，并且波长漂移的大小对应于微盘激光器的侧壁表面上的目标分析物的质量负载。
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公开(公告)号：US09994463B2
公开(公告)日：2018-06-12
申请号：US12967172
申请日：2010-12-14
申请人： Armin R. Volkel , Meng H. Lean , Kai Melde
发明人： Armin R. Volkel , Meng H. Lean , Kai Melde
摘要： An electrocoagulation system including a dosing unit, a mixing unit and a buffer tank is provided. The dosing unit receives a fluid from an external source and injects an electrochemically generated coagulant into the fluid using one or more pairs of electrodes. The mixing unit mixes the coagulant with the fluid and is separate from the dosing unit. The buffer tank holds the fluid until particles contained in the fluid grow to a predetermined size.
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公开(公告)号：US09486812B2
公开(公告)日：2016-11-08
申请号：US12120093
申请日：2008-05-13
申请人： Meng H. Lean , Jeonggi Seo , Ashutosh Kole , Armin R. Volkel
发明人： Meng H. Lean , Jeonggi Seo , Ashutosh Kole , Armin R. Volkel
摘要： Fluidic structures for facilitating particle separation in curved or spiral devices are provided. The contemplated systems relate to various fluidic structures, implementations and selected fabrication techniques to realize construction of fluidic separation structures that are of a stacked and/or parallel configuration. These contemplated systems provide for efficient input of fluid to be processed, improved throughput, and, in some variations, adjustable and efficient treatment of output fluid.
摘要翻译： 提供了用于促进弯曲或螺旋装置中的颗粒分离的流体结构。 考虑的系统涉及各种流体结构，实施方式和选择的制造技术，以实现具有堆叠和/或平行构造的流体分离结构的构造。 这些预期的系统提供了要处理的流体的有效输入，改善的产量，并且在一些变型中，可以对输出流体进行可调节和有效的处理。
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公开(公告)号：US08518235B2
公开(公告)日：2013-08-27
申请号：US12967147
申请日：2010-12-14
申请人： Armin R. Volkel , Meng H. Lean , Kai Melde , Norine E. Chang
发明人： Armin R. Volkel , Meng H. Lean , Kai Melde , Norine E. Chang
CPC分类号： B01D61/445 , C02F1/463 , C02F1/4674 , C02F1/4693 , C02F2001/46128 , C02F2201/4612 , C02F2209/06
摘要： A coagulation generating system that combines the advantages of conventional and electrocoagulation. In the coagulation generating system electro-coagulation is performed on an input (e.g., salt/brine) solution to generate a concentrated coagulant solution, which is then added to the source water in the same way as a standard stored chemical coagulant.
摘要翻译： 凝结生成系统，结合了传统和电凝的优点。 在凝结发生系统中，在输入（例如盐/盐水）溶液上进行电凝，以产生浓缩的凝结剂溶液，然后以与标准储存的化学凝结剂相同的方式加入到源水中。
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公开(公告)号：US08290408B2
公开(公告)日：2012-10-16
申请号：US12049013
申请日：2008-03-14
申请人： Meng H. Lean , Shu Chang , Daniel L. Larner , Armin R. Volkel
发明人： Meng H. Lean , Shu Chang , Daniel L. Larner , Armin R. Volkel
CPC分类号： G03G15/0803 , G03G15/065
摘要： An improved method and system for non-contact powder image development are provided. The present technique implements a 5-stage jumping development cycle where the initial stage is a momentary over-voltage condition to release the majority of the toner on a donor substrate and the final stage includes the implementation of a decelerating potential to minimize return impact on the donor and therefore toner abuse. It also uses a routine to directly determine improved (e.g. up to optimal) waveform amplitudes and pulse widths based on toner size and q/m, guided by physical insight.
摘要翻译： 提供了一种改进的非接触式粉末图像显影方法和系统。 本技术实现了5级跳跃开发周期，其中初始阶段是瞬时过电压条件以释放供体衬底上的大部分调色剂，并且最终阶段包括实现减速电位以最小化对 捐赠者，因此墨粉滥用。 它还使用程序直接根据物理洞察力来确定基于调色剂尺寸和q / m的改进（例如，最佳）波形幅度和脉冲宽度。
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