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1.发明申请AXIALLY ANCHORING COLLAPSIBLE AND RE-EXPANDABLE PROSTHETIC HEART VALVES FOR VARIOUS DISEASE STATES 有权对各种疾病状态进行轴向锚定和可再膨胀的预防心脏瓣膜公开(公告)号：US20110098800A1
公开(公告)日：2011-04-28
申请号：US12737254
申请日：2009-07-15
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2230/008
摘要： A stent (10) for use in a prosthetic heart valve has an annulus section (12) adapted for placement within the leaflets and annulus of the native heart valve. The annulus section has latch members (50) adapted to engage the leaflets of the native heart valve when prosthetic valve is implanted in the native valve. The latch members may hold the leaflets in engagement with the annulus section, and help to retain the prosthetic valve in position. The annulus section may have a non-circular cross-sectional shape.
摘要翻译： 用于假体心脏瓣膜的支架（10）具有适于放置在天然心脏瓣膜的瓣叶和环状物中的环形部分（12）。 环形部分具有闩锁构件（50），当人工瓣膜植入天然瓣膜时，该构件适于接合天然心脏瓣膜的小叶。 闩锁构件可以将小叶保持与环形部分接合，并且有助于将假体瓣保持在适当位置。 环形部分可以具有非圆形横截面形状。
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公开(公告)号：US20120078347A1
公开(公告)日：2012-03-29
申请号：US13203627
申请日：2010-02-25
申请人： Peter N. Braido , Yousef F. Alkhatib , Thomas M. Benson , Aaron J. Chalekian , Ott Khouengboua , Julia A. Neuman
发明人： Peter N. Braido , Yousef F. Alkhatib , Thomas M. Benson , Aaron J. Chalekian , Ott Khouengboua , Julia A. Neuman
CPC分类号： A61F2/2418 , A61F2/915 , A61F2002/91575 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067 , A61F2230/008
摘要： A prosthetic heart valve includes a stent having an expanded condition and a collapsed condition. The stent includes a plurality of distal cells, a plurality of proximal cells, a plurality of support struts coupling the proximal cells to the distal cells, and at least one support post connected to a plurality of proximal cells. The proximal cells are longitudinally spaced apart from the distal cells. Various strut configurations and connections of the struts to the proximal cells and of the proximal cells to the support post improve stent flexibility and reduce stress in the valve leaflets.
摘要翻译： 假体心脏瓣膜包括具有扩张状态和折叠状态的支架。 支架包括多个远端细胞，多个近端细胞，将近端细胞耦合到远端细胞的多个支撑支柱以及连接到多个近端细胞的至少一个支撑柱。 近端细胞与远端细胞纵向间隔开。 支柱结构和连接到近端细胞和近端细胞到支撑柱的各种支柱构型和连接可改善支架的灵活性并减少瓣膜小叶中的压力。
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3.发明授权Axially anchoring collapsible and re-expandable prosthetic heart valves for various disease states 有权用于各种疾病状态的轴向锚固可折叠和可再膨胀的假性心脏瓣膜公开(公告)号：US09226820B2
公开(公告)日：2016-01-05
申请号：US12737254
申请日：2009-07-15
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2230/008
摘要： A stent (10) for use in a prosthetic heart valve has an annulus section (12) adapted for placement within the ′ leaflets and annulus of the native heart valve. The annulus section has latch members (50) adapted to engage the leaflets of the native heart valve when prosthetic valve is implanted in the native valve. The latch members may hold the leaflets in engagement with the annulus section, and help to retain the prosthetic valve in position. The annulus section may have a non-circular cross-sectional shape.
摘要翻译： 用于假体心脏瓣膜的支架（10）具有适于放置在天然心脏瓣膜的小叶和环形空间内的环形部分（12）。 环形部分具有闩锁构件（50），当人工瓣膜植入天然瓣膜时，该构件适于接合天然心脏瓣膜的小叶。 闩锁构件可以将小叶保持与环形部分接合，并且有助于将假体瓣保持在适当位置。 环形部分可以具有非圆形横截面形状。
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公开(公告)号：US08808366B2
公开(公告)日：2014-08-19
申请号：US13203627
申请日：2010-02-25
申请人： Peter N. Braido , Yousef F. Alkhatib , Thomas M. Benson , Aaron J. Chalekian , Ott Khouengboua , Julia A. Neuman
发明人： Peter N. Braido , Yousef F. Alkhatib , Thomas M. Benson , Aaron J. Chalekian , Ott Khouengboua , Julia A. Neuman
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/915 , A61F2002/91575 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067 , A61F2230/008
摘要： A prosthetic heart valve includes a stent having an expanded condition and a collapsed condition. The stent includes a plurality of distal cells, a plurality of proximal cells, a plurality of support struts coupling the proximal cells to the distal cells, and at least one support post connected to a plurality of proximal cells. The proximal cells are longitudinally spaced apart from the distal cells. Various strut configurations and connections of the struts to the proximal cells and of the proximal cells to the support post improve stent flexibility and reduce stress in the valve leaflets.
摘要翻译： 假体心脏瓣膜包括具有扩张状态和折叠状态的支架。 支架包括多个远端细胞，多个近端细胞，将近端细胞耦合到远端细胞的多个支撑支柱以及连接到多个近端细胞的至少一个支撑柱。 近端细胞与远端细胞纵向间隔开。 支柱结构和连接到近端细胞和近端细胞到支撑柱的各种支柱构型和连接可改善支架的灵活性并减少瓣膜小叶中的压力。
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5.发明授权Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications 有权可折叠和可重新扩张的假体心脏瓣膜袖口设计和补充技术应用公开(公告)号：US08808356B2
公开(公告)日：2014-08-19
申请号：US12737256
申请日：2009-07-15
CPC分类号： A61F2/2409 , A61F2/01 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2442 , A61F2/246 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2230/0069 , A61F2250/0039 , A61F2250/0069
摘要： A prosthetic heart valve is provided with a cuff having features which promote sealing with the native tissues even where the native tissues are irregular. The cuff may include a portion adapted to bear on the LVOT when the valve is implanted in a native aortic valve. The valve may include elements for biasing the cuff outwardly with respect to the stent body when the stent body is in an expanded condition. The cuff may have portions of different thickness distributed around the circumference of the valve in a pattern matching the shape of the opening defined by the native tissue. All or part of the cuff may be movable relative to the stent during implantation.
摘要翻译： 假体心脏瓣膜设置有具有促进与天然组织密封的特征的袖带，即使天然组织是不规则的。 当瓣膜植入天然主动脉瓣中时，套囊可以包括适于承受LVOT的部分。 当支架主体处于膨胀状态时，阀可以包括用于相对于支架主体向外偏压套囊的元件。 袖带可以具有以与由天然组织限定的开口的形状相匹配的图案围绕阀的圆周分布的不同厚度的部分。 在植入期间，全部或部分袖带可相对于支架移动。
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公开(公告)号：US08425593B2
公开(公告)日：2013-04-23
申请号：US12733759
申请日：2008-09-26
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.
摘要翻译： 假体心脏瓣膜可折叠到相对较小的圆周尺寸以便较少侵入性地输送到患者体内，然后在患者的植入部位再扩张至操作尺寸，包括可折叠/可扩张的支架状支撑结构和各种部件 柔性的片状材料，其附接到支撑结构。 例如，这些片状的其他部件可以包括假体瓣膜小叶，缓冲材料层，袖带材料等。提供了改进的结构和技术，用于将这些其它部件固定到瓣膜的支架状支撑结构上。
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7.发明申请公开(公告)号：US20110098802A1
公开(公告)日：2011-04-28
申请号：US12737256
申请日：2009-07-15
CPC分类号： A61F2/2409 , A61F2/01 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/2442 , A61F2/246 , A61F2/2466 , A61F2210/0014 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0054 , A61F2230/0069 , A61F2250/0039 , A61F2250/0069
摘要： A prosthetic heart valve is provided with a cuff (85, 285, 400) having features which promote sealing with the native tissues even where the native tissues are irregular. The cuff may include a portion (90) adapted to bear native aortic valve. The valve may include elements (210, 211, 230, 252, 253) for biasing the cuff outwardly with respect to the stent body when the stent body is in an expanded condition. The cuff may have portions of different thickness (280) distributed around the circumference of the valve in a pattern matching the shape of the opening defined by the native tissue. All or part (402) of the cuff may be movable relative to the stent during implantation.
摘要翻译： 假体心脏瓣膜具有袖带（85,285,400），其具有促进与天然组织密封的特征，即使天然组织是不规则的。 袖带可以包括适于承载原生主动脉瓣的部分（90）。 当支架主体处于膨胀状态时，阀可以包括用于相对于支架主体向外偏压套囊的元件（210,211,230,252,253）。 袖带可以具有以与天然组织限定的开口的形状相匹配的图案围绕阀的圆周分布的不同厚度（280）的部分。 袖带的全部或部分（402）在植入期间可相对于支架移动。
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公开(公告)号：US20100185277A1
公开(公告)日：2010-07-22
申请号：US12733759
申请日：2008-09-26
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/2403 , A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2433 , A61F2/89 , A61F2220/0008 , A61F2220/0075 , A61F2230/0006 , A61F2230/0054 , A61F2230/0069
摘要： Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc. Improved structures and techniques are provided for securing such other components to the stent-like supporting structure of the valve.
摘要翻译： 假体心脏瓣膜可折叠到相对较小的圆周尺寸以便较少侵入性地输送到患者体内，然后在患者的植入部位再扩张至操作尺寸，包括可折叠/可扩张的支架状支撑结构和各种部件 柔性的片状材料，其附接到支撑结构。 例如，这些片状的其他部件可以包括假体瓣膜小叶，缓冲材料层，袖带材料等。提供了改进的结构和技术，用于将这些其它部件固定到瓣膜的支架状支撑结构上。
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公开(公告)号：US07246785B2
公开(公告)日：2007-07-24
申请号：US10439842
申请日：2003-05-19
IPC分类号： A47F5/00
CPC分类号： F16F1/027 , F16F1/373 , F16F7/00 , F16F15/08 , Y10S248/917
摘要： A shock isolated operator station wherein a set of quadral elastomer mounts provide substantial static support as well as isolate equipment supported thereon from shock and vibrations forces.
摘要翻译： 震动隔离操作员站，其中一组四通弹性体安装件提供实质的静态支撑，以及隔离受其振动和振动力的设备。
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公开(公告)号：USD492676S1
公开(公告)日：2004-07-06
申请号：US29174640
申请日：2003-01-20
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