公开(公告)号：US20050194142A1

公开(公告)日：2005-09-08

申请号：US10793711

申请日：2004-03-05

申请人： Philip Nguyen ,  Johnny Barton ,  David Brown

发明人： Philip Nguyen ,  Johnny Barton ,  David Brown

IPC分类号： C09K8/50 ,  C09K8/62 ,  E21B43/267 ,  E21B33/138

CPC分类号： C09K8/50 ,  C09K8/62

摘要： The present invention relates to methods for stabilizing an unconsolidated or weakly consolidated zone of a subterranean formation. One embodiment provides a method of stabilizing a subterranean formation comprising the steps of placing a gelable liquid composition into the subterranean formation, wherein the gelable liquid composition is capable of forming a gelled substance after placement; and, allowing the gelable liquid composition to convert into a gelled substance that stabilizes unconsolidated or weakly consolidated particles within the subterranean formation. Another embodiment provides a method of stimulating production from a subterranean formation comprising the steps of placing a gelable liquid composition into the subterranean formation; allowing the gelable liquid composition to convert into a gelled substance; creating at least one fracture in the subterranean formation extending from the well bore, through the gelled substance, and into an untreated zone of the subterranean formation; depositing proppant into at least one such fracture.

摘要翻译： 本发明涉及用于稳定地层的未固结或弱固结区的方法。 一个实施方案提供了一种稳定地层的方法，包括将可胶凝液体组合物置于地层中的步骤，其中可凝胶化液体组合物能够在放置后形成凝胶物质; 并且允许可凝胶化液体组合物转化成使地下地层内未固化或弱固化的颗粒稳定的凝胶物质。 另一个实施方案提供了一种刺激地层生产的方法，包括将可胶凝液体组合物置于地层中的步骤; 使可凝胶化的液体组合物转变为凝胶状物质; 在地下地层中产生至少一个从井眼延伸穿过凝胶物质并进入地下地层的未处理区域的裂缝; 将支撑剂沉积到至少一个这样的断裂中。

公开(公告)号：US20050274520A1

公开(公告)日：2005-12-15

申请号：US11204804

申请日：2005-08-16

申请人： Philip Nguyen ,  David Brown

发明人： Philip Nguyen ,  David Brown

IPC分类号： C09K8/512 ,  C09K8/575 ,  E21B33/138

CPC分类号： C09K8/5756 ,  C09K8/512

摘要： The present invention provides methods of reducing the production of both water and particulates from subterranean formations; the methods are particularly useful in conjunction with subterranean formations surrounding wellbores and fractures. The methods comprise the steps of applying to a subterranean formation a pre-flush fluid, applying aqueous surfactant fluid, applying a low-viscosity consolidating fluid, and applying an after-flush fluid.

公开(公告)号：US20050079981A1

公开(公告)日：2005-04-14

申请号：US10684697

申请日：2003-10-14

申请人： Philip Nguyen ,  David Brown ,  Bhadra Desai

发明人： Philip Nguyen ,  David Brown ,  Bhadra Desai

IPC分类号： C09K8/50 ,  C09K8/508 ,  C09K8/68 ,  E21B43/00

CPC分类号： C09K8/50 ,  C09K8/5083 ,  C09K8/68

摘要： The present invention relates to treatment operations in subterranean zones, and more particularly, to consolidation compositions and methods of using these consolidation compositions to mitigate water production from subterranean formations. The present invention provides methods for mitigating the production of water from a subterranean formation by injecting consolidation compositions comprising a furan-based resin into an interval in the subterranean formation.

摘要翻译： 本发明涉及在地下区域中的处理操作，更具体地说，涉及使用这些固结组合物以减轻地下地层产水量的固结组合物和方法。 本发明提供了通过将包含呋喃基树脂的固化组合物注入到地层中的间隔中来减轻来自地下地层的水的生产的方法。

公开(公告)号：US20070249615A1

公开(公告)日：2007-10-25

申请号：US11737966

申请日：2007-04-20

申请人： Robert Hughes ,  Andrew Bell ,  David Brown ,  Dafydd Owen ,  Michael Palmer ,  Christopher Phillips ,  David Brown ,  Yvette Fobian ,  John Freskos ,  Steven Heasley ,  E. Jacobsen ,  Todd Maddux ,  Brent Mischke ,  John Molyneaux ,  Joseph Moon ,  D. Rogier ,  Michael Tollefson ,  John Walker

发明人： Robert Hughes ,  Andrew Bell ,  David Brown ,  Dafydd Owen ,  Michael Palmer ,  Christopher Phillips ,  David Brown ,  Yvette Fobian ,  John Freskos ,  Steven Heasley ,  E. Jacobsen ,  Todd Maddux ,  Brent Mischke ,  John Molyneaux ,  Joseph Moon ,  D. Rogier ,  Michael Tollefson ,  John Walker

IPC分类号： A61K31/498 ,  C07D487/02

CPC分类号： C07D471/04

摘要： Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: wherein R2, R6A, R6B and R8 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, synthetic methods, and intermediates are also disclosed.

摘要翻译： 公开了化合物的化合物和药学上可接受的盐，其中所述化合物具有式I的结构：其中R 2，R 6A，R 6B， >和R＆gt; 8如说明书中所定义。 还公开了相应的药物组合物，治疗方法，合成方法和中间体。

公开(公告)号：US20240026317A1

公开(公告)日：2024-01-25

申请号：US18249023

申请日：2021-10-13

申请人： Dong SHEN ,  David BROWN ,  Renxiang CHEN ,  RNAimmune, Inc

发明人： Dong Shen ,  David Brown ,  Renxiang Chen

IPC分类号： C12N9/14 ,  C12P19/30 ,  A61K39/00 ,  A61K9/127 ,  A61K47/69 ,  A61P35/00 ,  A61K47/54

CPC分类号： C12N9/14 ,  C12Y306/05002 ,  C12P19/30 ,  A61K39/001164 ,  A61K9/1273 ,  A61K47/6911 ,  A61P35/00 ,  A61K47/54 ,  A61K2039/53 ,  A61K2039/585 ,  A61K2039/55555

摘要： Compositions and methods are provided for potent mRNA vaccines for treatment of cancers with a mutation in the ras gene family. The compositions include a pharmaceutical composition comprising, or consisting essentially of, or yet further comprising mRNA molecules encoding at least one of multiple peptides of a group of somatic mutants and a pharmaceutically acceptable carrier. Methods for stimulating system immune responses and treatment are provided, including intratumoral, intravenous, intramuscular, intradermal, or subcutaneous injection of the composition as disclosed herein.

公开(公告)号：US11345606B2

公开(公告)日：2022-05-31

申请号：US15435318

申请日：2017-02-17

申请人： David Brown

发明人： David Brown

IPC分类号： G02B6/02 ,  C01G23/053 ,  C01G49/06 ,  C01B33/18

摘要： Disclosed is a method for producing deposition particles or intermediate particles, characterized in that the method comprises: forming a solution comprising a solvent and one or more deposit sources, aerosolizing the formed solution to produce an aerosol of precursor particles comprising the deposit source, conditioning the precursor particles to produce deposition particles or intermediate particles from the deposit source and collecting said particles. The particles may be collected as a deposit or precursor deposit on a substrate. The particles may include a matrix material and a dopant. The conditioning may be quenched to produce a desired substructure. The matrix material may be essentially optically clear. The substrate may comprise an optical fiber or an optical fiber preform or mandrel.

公开(公告)号：USD819777S1

公开(公告)日：2018-06-05

申请号：US29581051

申请日：2016-10-14

申请人： David Brown

设计人： David Brown

公开(公告)号：US20170128079A1

公开(公告)日：2017-05-11

申请号：US15343765

申请日：2016-11-04

申请人： David Brown

发明人： David Brown

IPC分类号： A61B17/15

CPC分类号： A61B17/155

摘要： An integrated instrument for arthroplasty planning comprises a cutting block having an adjustable distance between an anterior cut guide and a posterior cut guide, and a sizer mounted to the cutting block, the sizer comprising medial and lateral posterior feet having an adjustable distance from one of the cut guides and an adjustable angular position relative to the one of the cut guides.

公开(公告)号：US09612287B2

公开(公告)日：2017-04-04

申请号：US13461862

申请日：2012-05-02

申请人： David Brown ,  Christopher James Belcher ,  Duncan Joseph Brown ,  Dat Tan Chau

发明人： David Brown ,  Christopher James Belcher ,  Duncan Joseph Brown ,  Dat Tan Chau

IPC分类号： H02J7/00 ,  G01R31/36 ,  H02J9/04

CPC分类号： G01R31/3631 ,  G01R31/3658 ,  G01R31/3662 ,  H02J7/0021 ,  H02J9/04

摘要： Non-sequential monitoring of battery cells in battery monitoring systems, and related components, systems, and methods are disclosed. In one embodiment, a battery monitoring system control unit is provided. The battery monitoring system control unit is configured to control battery monitoring devices. Each battery monitoring device is configured to be coupled to a subset of battery cells electrically connected in series in a sequential order to form a battery. The battery monitoring system control unit is further configured to instruct the battery monitoring devices to test an ohmic value of each battery cell of the battery cells of the battery in a non-sequential order. In this manner, heat generated in the battery monitoring devices from the testing may be more effectively dissipated, which can also allow for the battery monitoring devices to be employed in higher operating temperature environments.

公开(公告)号：US20160130026A1

公开(公告)日：2016-05-12

申请号：US14534692

申请日：2014-11-06

申请人： David Brown ,  Sheletia Brown

发明人： David Brown ,  Sheletia Brown

IPC分类号： B65D1/02 ,  B65D41/04 ,  B65D47/06 ,  B65D1/40

CPC分类号： B65D1/0292 ,  B65D1/0284 ,  B65D1/40 ,  B65D2501/0036

摘要： A collapsible beverage containment assembly includes a bottle. The bottle has an outer wall extending between a top end and a bottom end of the bottle to contain a carbonated fluid. The outer wall is structured such that the bottle is collapsible. A sleeve is coupled to the bottom end. The sleeve is positioned within an interior of the bottle. A lid is movably coupled to the top end so the lid may be rotated. A screw is coupled to the lid such that the screw extends downwardly into the bottle. The screw engages the sleeve. Thus, the outer wall is collapsed when the lid is rotated to reduce a volume of the bottle, preserving the carbonation in the carbonated beverage.

摘要翻译： 可折叠的饮料容纳组件包括瓶子。 瓶子具有在瓶的顶端和底端之间延伸以容纳碳酸液体的外壁。 外壁的结构使得瓶子可折叠。 套筒连接到底端。 套筒位于瓶子的内部。 盖子可移动地联接到顶端，因此盖子可以旋转。 螺钉联接到盖上，使得螺钉向下延伸到瓶中。 螺钉接合套筒。 因此，当盖旋转以减小瓶的体积时，外壁被折叠，从而保持碳酸饮料中的碳酸化。