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公开(公告)号:US06821757B2
公开(公告)日:2004-11-23
申请号:US09341119
申请日:1999-11-18
申请人: Philippe Sauer , Jie Kang
发明人: Philippe Sauer , Jie Kang
IPC分类号: C12P1934
CPC分类号: C12N15/1006 , C07B2200/11 , C07H21/00 , C40B40/00
摘要: A method for separating and/or isolating circular nucleic acids from a mixture having different species of nucleic acids other than circular nucleic acids wherein the mixture is treated under alkaline conditions at a pH>8 with a solid matrix consisting essentially of a silica material in presence of at least one chaotropic substance.
摘要翻译: 用于从具有不同环状核酸种类的混合物分离和/或分离循环核酸的方法,其中所述混合物在pH> 8的碱性条件下处理,其中固体基质主要由二氧化硅材料组成, 的至少一种离液剂。
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2.
公开(公告)号:US07183002B2
公开(公告)日:2007-02-27
申请号:US10239112
申请日:2001-03-22
申请人: Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
发明人: Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
CPC分类号: B03C1/01 , B82Y25/00 , C12N15/1013 , H01F1/0054 , Y10T428/2982 , Y10T428/2993 , Y10T428/2996 , Y10T428/2998
摘要: Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules, under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use of identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
摘要翻译: 描述了多孔,铁或铁磁性玻璃颗粒,其在合适的条件下选择性地结合感兴趣的分子,特别是核酸分子。 还描述了制备多孔,铁或铁磁性玻璃颗粒的方法及其鉴定或分离感兴趣的分子的用途。 还提供了包含多孔,铁或铁磁性玻璃颗粒的试剂盒。
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3.
公开(公告)号:US07922917B2
公开(公告)日:2011-04-12
申请号:US11635304
申请日:2006-12-07
申请人: Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
发明人: Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
IPC分类号: C01G49/02
CPC分类号: B03C1/01 , B82Y25/00 , C12N15/1013 , H01F1/0054 , Y10T428/2982 , Y10T428/2993 , Y10T428/2996 , Y10T428/2998
摘要: Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules, under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use for identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
摘要翻译: 描述了多孔,铁或铁磁性玻璃颗粒,其在合适的条件下选择性地结合感兴趣的分子,特别是核酸分子。 还描述了制备多孔,铁或铁磁性玻璃颗粒的方法及其用于鉴定或分离目的分子的用途。 还提供了包含多孔,铁或铁磁性玻璃颗粒的试剂盒。
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4.
公开(公告)号:US08202427B2
公开(公告)日:2012-06-19
申请号:US13034217
申请日:2011-02-24
申请人: Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
发明人: Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
IPC分类号: B01D11/00
CPC分类号: B03C1/01 , B82Y25/00 , C12N15/1013 , H01F1/0054 , Y10T428/2982 , Y10T428/2993 , Y10T428/2996 , Y10T428/2998
摘要: Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules; under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use for identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
摘要翻译: 描述了多孔,铁或铁磁性玻璃颗粒,其选择性地结合感兴趣的分子,特别是核酸分子; 在适当的条件下。 还描述了制备多孔,铁或铁磁性玻璃颗粒的方法及其用于鉴定或分离目的分子的用途。 还提供了包含多孔,铁或铁磁性玻璃颗粒的试剂盒。
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5.
公开(公告)号:US20110186524A1
公开(公告)日:2011-08-04
申请号:US13034217
申请日:2011-02-24
申请人: Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
发明人: Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
CPC分类号: B03C1/01 , B82Y25/00 , C12N15/1013 , H01F1/0054 , Y10T428/2982 , Y10T428/2993 , Y10T428/2996 , Y10T428/2998
摘要: Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules; under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use for identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
摘要翻译: 描述了多孔,铁或铁磁性玻璃颗粒,其选择性地结合感兴趣的分子,特别是核酸分子; 在适当的条件下。 还描述了制备多孔,铁或铁磁性玻璃颗粒的方法及其用于鉴定或分离目的分子的用途。 还提供了包含多孔,铁或铁磁性玻璃颗粒的试剂盒。
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6.
公开(公告)号:US20070080316A1
公开(公告)日:2007-04-12
申请号:US11635304
申请日:2006-12-07
申请人: Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
发明人: Philippe Sauer , Bernd Springer , Thomas Manz , Christoph Ritt , Roland Fabis
CPC分类号: B03C1/01 , B82Y25/00 , C12N15/1013 , H01F1/0054 , Y10T428/2982 , Y10T428/2993 , Y10T428/2996 , Y10T428/2998
摘要: Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules, under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use for identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided.
摘要翻译: 描述了多孔,铁或铁磁性玻璃颗粒,其在合适的条件下选择性地结合感兴趣的分子,特别是核酸分子。 还描述了制备多孔,铁或铁磁性玻璃颗粒的方法及其用于鉴定或分离目的分子的用途。 还提供了包含多孔,铁或铁磁性玻璃颗粒的试剂盒。
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