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1.发明申请VOLATILE ANESTHETIC COMPOSITIONS COMPRISING EXTRACTIVE SOLVENTS FOR REGIONAL ANESTHESIA AND/OR PAIN RELIEF 有权包含用于区域性麻醉和/或疼痛缓解的提取溶剂的挥发性麻醉组合物公开(公告)号：US20110039944A1
公开(公告)日：2011-02-17
申请号：US12863755
申请日：2009-01-22
Applicant: Christopher C. Capelli , Phillip C. Phan , Allen W. Burton
Inventor： Christopher C. Capelli , Phillip C. Phan , Allen W. Burton
CPC classification number: A61K9/0014 , A61K9/0019 , A61K9/0085 , A61K9/107 , A61K9/127 , A61K31/02 , A61K31/08 , A61K47/20 , A61K47/22
Abstract: The present invention provides methods for reducing pain in a subject in need of such pain reduction by delivering, e.g., intrathecally or epidurally, a volatile anesthetic dissolved in a solution comprising an extractive solvent, e.g., DMSO or NMP, in an amount effective to reduce pain. Chronic or acute pain may be treated, or the anesthetic may be delivered as a regional anesthesia to a subject to anesthetize a portion the subject prior to a surgery, hi certain embodiments, isoflurane, halothane, enflurane, sevoflurane, desflurane, methoxyflurane, or mixtures thereof may be used. Dosing regimens including a one-time administration, continuous and/or periodic administration are contemplated.
Abstract translation: 本发明提供了通过递送（例如）鞘内或硬膜外地溶解在包含萃取溶剂（例如DMSO或NMP）的溶液中的挥发性麻醉剂来减少需要这种疼痛减轻的受试者的疼痛的方法，其量有效降低 疼痛。 可以治疗慢性或急性疼痛，或者麻醉剂可以作为局部麻醉递送给受试者，以在手术之前麻醉受试者的一部分。在某些实施方案中，异氟烷，氟烷，恩氟烷，七氟醚，地氟烷，甲氧氟烷或其混合物 可以使用。 预期包括一次给药，连续和/或定期给药的给药方案。
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公开(公告)号：US10357464B2
公开(公告)日：2019-07-23
申请号：US13183257
申请日：2011-07-14
Applicant: Phillip C. Phan , Allen W. Burton
Inventor： Phillip C. Phan , Allen W. Burton
Abstract: The present invention provides methods for reducing pain in a subject in need of such pain reduction by delivering, e.g., intrathecally or epidurally, a volatile anesthetic such as a halogenated ether compound in an amount effective to reduce pain. Chronic or acute pain may be treated, or the anesthetic may be delivered to the subject to anesthetize the subject prior to a surgery. In certain embodiments, isoflurane, halothane, enflurane, sevoflurane, desflurane, methoxyflurane, xenon, and mixtures thereof may be used. Dosing regimens including a one-time administration, continuous and/or periodic administration are contemplated.
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Patent Agency Ranking
公开(公告)号：US09675544B2
公开(公告)日：2017-06-13
申请号：US12863755
申请日：2009-01-22
Applicant: Christopher C. Capelli , Phillip C. Phan , Allen W. Burton
Inventor： Christopher C. Capelli , Phillip C. Phan , Allen W. Burton
CPC classification number: A61K9/0014 , A61K9/0019 , A61K9/0085 , A61K9/107 , A61K9/127 , A61K31/02 , A61K31/08 , A61K47/20 , A61K47/22
Abstract: The present invention provides methods for reducing pain in a subject in need of such pain reduction by delivering, e.g., intrathecally or epidurally, a volatile anesthetic dissolved in a solution comprising an extractive solvent, e.g., DMSO or NMP, in an amount effective to reduce pain. Chronic or acute pain may be treated, or the anesthetic may be delivered as a regional anesthesia to a subject to anesthetize a portion the subject prior to a surgery, hi certain embodiments, isoflurane, halothane, enflurane, sevoflurane, desflurane, methoxyflurane, or mixtures thereof may be used. Dosing regimens including a one-time administration, continuous and/or periodic administration are contemplated.
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公开(公告)号：US20110159078A1
公开(公告)日：2011-06-30
申请号：US12863757
申请日：2009-01-22
Applicant: Allen Burton , Phillip C. Phan , Hatice Ozsoy
Inventor： Allen Burton , Phillip C. Phan , Hatice Ozsoy
CPC classification number: A61K31/08 , A61K9/0014 , A61K9/0019 , A61K9/0024 , A61K9/0085 , A61K9/107 , A61K31/075 , A61K47/20 , A61K47/22
Abstract: The present invention provides methods for reducing pain in a subject in need thereof by delivering a volatile anesthetic in a solution or an emulsion that can additionally include an extractive solvent in an amount effective to reduce pain without substantially interfering with motor function. Chronic or acute pain may be treated, or the volatile anesthetic may be delivered as a regional anesthetic to a subject to anesthetize a portion of the subject prior to surgery. Dosing regimes including a one-time administration, continuous and/or periodic administration are contemplated.
Abstract translation: 本发明提供了通过将挥发性麻醉剂递送到溶液或乳剂中来减少需要的受试者的疼痛的方法，所述溶液或乳剂可另外包含有效降低疼痛而不基本上干扰运动功能的萃取溶剂。 可以治疗慢性或急性疼痛，或者挥发性麻醉剂可以作为局部麻醉剂递送给受试者，以在手术之前麻醉受试者的一部分。 预期包括一次给药，连续和/或定期给药的给药方案。
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5.发明申请Methods for Delivering Volatile Anesthetics for Regional Anesthesia and/or Pain Relief 审中-公开提供挥发性麻醉剂用于区域麻醉和/或止痛的方法公开(公告)号：US20080119820A1
公开(公告)日：2008-05-22
申请号：US11858497
申请日：2007-09-20
Applicant: Phillip C. Phan , Allen W. Burion
Inventor： Phillip C. Phan , Allen W. Burion
CPC classification number: A61K31/02 , A61K9/0019 , A61K9/08 , A61K31/07
Abstract: The present invention provides methods for reducing pain in a subject in need of such pain reduction by delivering, e.g., intrathecally or epidurally, a volatile anesthetic such as a halogenated ether compound in an amount effective to reduce pain. Chronic or acute pain may be treated, or the anesthetic may be delivered to the subject to anesthetize the subject prior to a surgery. In certain embodiments, isoflurane, halothane, enflurane, sevoflurane, desflurane, methoxyflurane, xenon, and mixtures thereof may be used. Dosing regimens including a one-time administration, continuous and/or periodic administration are contemplated.
Abstract translation: 本发明提供了通过例如鞘内或硬膜外递送挥发性麻醉剂如卤代醚化合物来降低疼痛的方法，所述方法通过有效减少疼痛的量减少需要减轻疼痛的受试者的疼痛。 可以治疗慢性或急性疼痛，或者在手术之前将麻醉剂递送到受试者麻醉受试者。 在某些实施方案中，可以使用异氟烷，氟烷，恩氟烷，七氟醚，地氟烷，甲氧基氟烷，氙及其混合物。 预期包括一次给药，连续和/或定期给药的给药方案。
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公开(公告)号：US20090171376A1
公开(公告)日：2009-07-02
申请号：US12092804
申请日：2006-11-07
Applicant: Allen Burton , Phillip C. Phan
Inventor： Allen Burton , Phillip C. Phan
IPC: A61B17/08
CPC classification number: A61M25/04 , A61M25/02 , A61M2025/0253 , A61N1/0558 , A61N2001/0582
Abstract: Medical devices configured for securing the position of a tube or wire in a desired position. Embodiments of the medical devices include an anchoring element and a mesh element coupled to the anchoring element. The medical device can be secured to the skin surface of a subject, or to muscle or fascia within a surgical incision. The medical device can be secured, for example, by stapling the mesh element to underlying skin or tissue.
Abstract translation: 被配置为将管或线的位置固定在期望位置的医疗装置。 医疗装置的实施例包括锚定元件和联接到锚定元件的网状元件。 医疗装置可以固定到受试者的皮肤表面，或外科切口内的肌肉或筋膜上。 医疗装置可以例如通过将网状物件装订到下面的皮肤或组织来固定。
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7.发明申请METHODS FOR DELIVERING VOLATILE ANESTHETICS FOR REGIONAL ANESTHESIA AND/OR PAIN RELIEF 审中-公开为区域性麻醉和/或疼痛救济提供挥发性麻醉方法公开(公告)号：US20110269843A1
公开(公告)日：2011-11-03
申请号：US13183257
申请日：2011-07-14
Applicant: Phillip C. Phan , Allen W. Burion
Inventor： Phillip C. Phan , Allen W. Burion
CPC classification number: A61K31/02 , A61K9/0019 , A61K9/08 , A61K31/07
Abstract: The present invention provides methods for reducing pain in a subject in need of such pain reduction by delivering, e.g., intrathecally or epidurally, a volatile anesthetic such as a halogenated ether compound in an amount effective to reduce pain. Chronic or acute pain may be treated, or the anesthetic may be delivered to the subject to anesthetize the subject prior to a surgery. In certain embodiments, isoflurane, halothane, enflurane, sevoflurane, desflurane, methoxyflurane, xenon, and mixtures thereof may be used. Dosing regimens including a one-time administration, continuous and/or periodic administration are contemplated.
Abstract translation: 本发明提供了通过例如鞘内或硬膜外递送挥发性麻醉剂如卤代醚化合物来降低疼痛的方法，所述方法通过有效减少疼痛的量减少需要减轻疼痛的受试者的疼痛。 可以治疗慢性或急性疼痛，或者在手术之前将麻醉剂递送到受试者麻醉受试者。 在某些实施方案中，可以使用异氟烷，氟烷，恩氟烷，七氟醚，地氟烷，甲氧基氟烷，氙及其混合物。 预期包括一次给药，连续和/或定期给药的给药方案。
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