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1.发明申请Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers 有权针对P-糖蛋白170的治疗性疫苗用于抑制癌症治疗中的多药耐药性公开(公告)号：US20110064795A1
公开(公告)日：2011-03-17
申请号：US12870893
申请日：2010-08-30
CPC分类号： A61K39/0005 , A61K39/0011 , A61K2039/55505 , A61K2039/55555 , A61K2039/6018
摘要： The invention relates to an immunogenic composition which comprises, firstly, a carrier and, secondly, as antigenic structure, conjugates comprising all or part of the amino acid sequences of at least one peptide derived from an extracellular loop of the P-170 protein, each peptide being combined with several molecules of fatty acid containing a carbon chain of between C12 and C24 so as to allow, under suitable administration conditions, the induction of anti-P-170 antibodies.
摘要翻译： 本发明涉及免疫原性组合物，其首先包括载体，其次，作为抗原结构，包含衍生自P-170蛋白的细胞外环的至少一种肽的全部或部分氨基酸序列的缀合物，各自 肽与几个含有C12和C24之间的碳链的脂肪酸分子组合，以便在合适的施用条件下允许诱导抗P-170抗体。
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2.发明申请Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers 有权针对P-糖蛋白170的治疗性疫苗用于抑制癌症治疗中的多药耐药性公开(公告)号：US20050175615A1
公开(公告)日：2005-08-11
申请号：US10902276
申请日：2004-07-30
IPC分类号： A61K39/00 , A61K39/395
CPC分类号： A61K39/0005 , A61K39/0011 , A61K2039/55505 , A61K2039/55555 , A61K2039/6018
摘要： The invention relates to an immunogenic composition which comprises, firstly, a carrier and, secondly, as antigenic structure, conjugates comprising all or part of the amino acid sequences of at least one peptide derived from an extracellular loop of the P-170 protein, each peptide being combined with several molecules of fatty acid containing a carbon chain of between C12 and C24 so as to allow, under suitable administration conditions, the induction of anti-P-170 antibodies. The invention relates to said composition for defining means for treating multidrug resistances.
摘要翻译： 本发明涉及免疫原性组合物，其首先包括载体，其次，作为抗原结构，包含衍生自P-170蛋白的细胞外环的至少一种肽的全部或部分氨基酸序列的缀合物，各自 肽与几个含有C12和C24之间的碳链的脂肪酸分子组合，以便在合适的施用条件下允许诱导抗P-170抗体。 本发明涉及用于定义用于治疗多药耐药性的装置的所述组合物。
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3.发明申请公开(公告)号：US20050244419A1
公开(公告)日：2005-11-03
申请号：US11038501
申请日：2005-01-21
IPC分类号： A61K39/00
CPC分类号： A61K39/0005 , A61K39/0011 , A61K2039/55505 , A61K2039/55555 , A61K2039/6018
摘要： The invention relates to an immunogenic composition which comprises, firstly, a carrier and, secondly, as antigenic structure, conjugates comprising all or part of the amino acid sequences of at least one peptide derived from an extracellular loop of the P-170 protein, each peptide being combined with several molecules of fatty acid containing a carbon chain of between C12 and C24 so as to allow, under suitable administration conditions, the induction of anti-P-170 antibodies. The invention relates to said composition for defining means for treating multidrug resistances.
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