公开(公告)号：US11638748B2

公开(公告)日：2023-05-02

申请号：US17015177

申请日：2020-09-09

Applicant: President and Fellows of Harvard College

Inventor： Michael Super ,  Edward J. Doherty ,  Mark Joseph Cartwright ,  Des White ,  Alexander Stafford ,  Omar Abdel-Rahman Ali ,  Amanda Graveline ,  Donald E. Ingber ,  David J. Mooney ,  Benjamin Seiler

IPC: A61K39/02 ,  A61K39/108 ,  A61K39/00

Abstract: The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a pathogen in a subject having a pathogen infection, methods of increasing the surviving rate of a subject having a pathogen infection, methods of reducing the level of pain associated with a pathogen infection, and methods of reducing the level of distress associated with a pathogen infection in a subject in need thereof. Novel scaffold compositions and opsonin-bound or lectin-bound pathogen compositions, and uses thereof, are also provided herein.

公开(公告)号：US20240108709A1

公开(公告)日：2024-04-04

申请号：US18186588

申请日：2023-03-20

Applicant: President and Fellows of Harvard College

Inventor： Michael Super ,  Edward J. Doherty ,  Mark Joseph Cartwright ,  Des White ,  Alexander Stafford ,  Omar Abdel-Rahman Ali ,  Amanda Graveline ,  Donald E. Ingber ,  David J. Mooney ,  Benjamin Seiler

IPC: A61K39/108 ,  A61K39/02

CPC classification number: A61K39/0258 ,  A61K39/025 ,  A61K2039/6093

Abstract: The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a pathogen in a subject having a pathogen infection, methods of increasing the surviving rate of a subject having a pathogen infection, methods of reducing the level of pain associated with a pathogen infection, and methods of reducing the level of distress associated with a pathogen infection in a subject in need thereof. Novel scaffold compositions and opsonin-bound or lectin-bound pathogen compositions, and uses thereof, are also provided herein.

公开(公告)号：US20210170007A1

公开(公告)日：2021-06-10

申请号：US17015177

申请日：2020-09-09

Applicant: President and Fellows of Harvard College

Inventor： Michael Super ,  Edward J. Doherty ,  Mark Joseph Cartwright ,  Des White ,  Alexander Stafford ,  Omar Abdel-Rahman Ali ,  Amanda Graveline ,  Donald E. Ingber ,  David J. Mooney ,  Benjamin Seiler

IPC: A61K39/108 ,  A61K39/02

Abstract: The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a pathogen in a subject having a pathogen infection, methods of increasing the surviving rate of a subject having a pathogen infection, methods of reducing the level of pain associated with a pathogen infection, and methods of reducing the level of distress associated with a pathogen infection in a subject in need thereof. Novel scaffold compositions and opsonin-bound or lectin-bound pathogen compositions, and uses thereof, are also provided herein.

公开(公告)号：US10813988B2

公开(公告)日：2020-10-27

申请号：US15434781

申请日：2017-02-16

Applicant: President and Fellows of Harvard College

Inventor： Michael Super ,  Edward J. Doherty ,  Mark Cartwright ,  Des White ,  Alexander G. Stafford ,  Omar Abdel-Rahman Ali ,  Amanda Graveline ,  Donald E. Ingber ,  David J. Mooney ,  Benjamin Seiler

IPC: A61K39/108 ,  A61K39/02 ,  A61K39/00

Abstract: The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a pathogen in a subject having a pathogen infection, methods of increasing the surviving rate of a subject having a pathogen infection, methods of reducing the level of pain associated with a pathogen infection, and methods of reducing the level of distress associated with a pathogen infection in a subject in need thereof. Novel scaffold compositions and opsonin-bound or lectin-bound pathogen compositions, and uses thereof, are also provided herein.

公开(公告)号：US20170246281A1

公开(公告)日：2017-08-31

申请号：US15434781

申请日：2017-02-16

Applicant: President and Fellows of Harvard College

Inventor： Michael Super ,  Edward J. Doherty ,  Mark Cartwright ,  Des White ,  Alexander G. Stafford ,  Omar Abdel-Rahman Ali ,  Amanda Graveline ,  Donald E. Ingber ,  David J. Mooney ,  Benjamin Seiler

IPC: A61K39/108 ,  A61K39/02

Abstract: The present invention provides vaccine compositions and methods of producing such compositions. Other embodiments of the invention include methods of treating a pathogen infection, methods of vaccinating a subject against a pathogen infection, and methods for treating an antibiotic-resistance bacterial infection in a subject in need thereof. In further embodiments, the invention includes methods of decreasing the level of a pathogen in a subject having a pathogen infection, methods of increasing the surviving rate of a subject having a pathogen infection, methods of reducing the level of pain associated with a pathogen infection, and methods of reducing the level of distress associated with a pathogen infection in a subject in need thereof. Novel scaffold compositions and opsonin-bound or lectin-bound pathogen compositions, and uses thereof, are also provided herein.